...expression of the FAP. A new photosensitizer: FAP-TAP MG-2I-dL5** MG-2I-dL5** is a new FAP-TAP complex where...protein partner thus forming the full FAP-TAP complex (MG-2I-dL5**).   A FAP-TAP complex will light up if excited...composed of two parts: 1) an activatable protein (the FAP - fluorogen activating protein - dL5** in this case... where dL5** is the FAP. It’s job is to bind MG-2I, a photosensitizer fluorogenic dye.  MG-2I is the TAP...increased ROS generation when bound by the dL5** FAP.  The iodine-modifications also shift MG-2I’s excitation...Above is a brief schematic of how the MG-2I-dL5** FAP-TAP system works. Find the Plasmids from the Publication...zebrafish’s heartbeat and blood circulation of following FAP-TAP light activation. Video: https://www.youtube....

...incorporation (Figure 1d). Fluorogen activating proteins (FAPs) – These modified antibody fragments bind and enhance...strategies such as the bisarsenical dye (Figure 1a) and FAP systems (Figure 1e) are inherently fluorogenic and...

...as synapsin, glial fibrillary associated protein (GFAP), or tyrosine-hydroxylase (TH), can limit which ...Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat... & Brenner, M. (2004). Expression specificity of GFAP transgenes. Neurochemical Research, 29(11 SPEC. ...

... [Archon1-KGC-GFP-ER2] pAAV-FLEX-tdTomato pAAV-GFAP104-mCherry pAAV-mDlx-NLS-mRuby2 CAG-NLS-GFP pAAV-hSyn-mCherry...molecular tool.   Find pAAV-FLEX-tdTomato, pAAV-GFAP104-mCherry, pAAV-mDlx-NLS-mRuby2, CAG-NLS-GFP,and ...

...catecholamine neurons or glial fibrillary acidic protein (GFAP) for astrocytes it is important to test it in the...Additionally, some neurons express low levels of GFAP, which can lead to off-target expression of the ...

...using the chemogenetic tool hM4D(Gi) driven by a GFAP promoter in rat. Contribute your AAV data Just ...

...hSynap-FLP: Synapsin-1 promoter, FLP-dependent expression GFAP: Glial fibrillary acidic protein (promoter). Good...

...the Loren Looger Lab now available in AAV1. Get GFAP.SF-iGluSnFR.A184S-AAV1 here New Dual and Triple ...

...microglial/macrophage (mpeg1.1), and astrocytic (gfap).This toolbox adds new neuronal tools to the expanding...