CRISPR-mediated Plant Base Editors
Type
Blog Post
Published
Jan. 3, 2019, 1:35 p.m.
...satisfactorily accepts DNA as its substrate (see figure 2).
The artificially evolved adenosine deaminase...available for plant systems. Target-AID based (CBE-2)- and rAPOBEC based (CBE-1)- CBEs are successful...based CBEs are known to deaminate cytosine placed in 2-6 bp and 4-8 bp, respectively, of the protospacer....PMID: 27096365. PubMed Central PMCID: PMC4873371.
2. Nishida, Keiji, et al. "Targeted nucleotide editing...KKH
TadA-TadA*
NNNRRT
8
SpCas9-VRER
TadA-TadA*
NGCG
8
Tips for designing base editing experiments...