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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 3 results for: adar

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Showing: 1 - 3 of 3 results

  1. CRISPR Guide

    Type
    Collection
    ...on a second ADAR variant that displays improved specificity, and editors carrying an ADAR truncation that...hyperactive adenosine deaminase that acts on RNA, ADAR2(E488Q) fused to catalytically dead Cas13b to create...

  2. CRISPR Plasmids - RNA Editing

    Type
    Collection
    ...effects of ADAR2 by destabilizing its RNA binding. Editors carrying the delta-984–1090 ADAR2 truncation...rather than DNA. Fusing the catalytic domain of ADAR2(E488Q) adenosine deaminase to catalytically dead...

  3. CRISPR History and Development for Genome Engineering

    Type
    Collection
    ... to guanosine. RNA editors : Cas13 fused to the ADAR2 deaminase convert adenosine to inosine on RNA. Inosine...double-strand breaks. In mammalian cells, Cas13-ADAR2 does not require a specific flanking sequence on...
Showing: 1 - 3 of 3 results