... widely used Cry2-CIB1 system, light induces a conformational change in cryptochrome Cry2 to permit CIB1...protein of interest. A genetically-encoded nuclear Cry2 fusion can thus direct a CIB1-protein fusion to ...protein, such as the Cre recombinase, is fused to Cry2 and the other half to CIB1, light-stimulated heterodimerization...design of synthetic two-part transcription factors - Cry2 and CIB1 are fused to a transcriptional activation...effectors OPTOSTIM PHR domain2 of cryptochrome 2 (Cry2) from Arabidopsis thaliana is fused to truncated...