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pLVTHM Citations (167)

Originally described in: Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference.
Wiznerowicz M, Trono D J Virol. 2003 Aug . 77(16):8957-61.
PubMed Journal

Articles Citing pLVTHM

ERK2 protein regulates the proliferation of human mesenchymal stem cells without affecting their mobilization and differentiation potential. Carcamo-Orive I, Tejados N, Delgado J, Gaztelumendi A, Otaegui D, Lang V, Trigueros C. Exp Cell Res. 2008 May 1;314(8):1777-88. doi: 10.1016/j.yexcr.2008.01.020. Epub 2008 Feb 6. PubMed
A polypyrimidine tract-binding protein-dependent pathway of mRNA stability initiates with CpG activation of primary B cells. Porter JF, Vavassori S, Covey LR. J Immunol. 2008 Sep 1;181(5):3336-45. PubMed
Requirement of IFN-gamma-mediated indoleamine 2,3-dioxygenase expression in the modulation of lymphocyte proliferation by human adipose-derived stem cells. DelaRosa O, Lombardo E, Beraza A, Mancheno-Corvo P, Ramirez C, Menta R, Rico L, Camarillo E, Garcia L, Abad JL, Trigueros C, Delgado M, Buscher D. Tissue Eng Part A. 2009 Oct;15(10):2795-806. doi: 10.1089/ten.TEA.2008.0630. PubMed
Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines. Du ZW, Hu BY, Ayala M, Sauer B, Zhang SC. Stem Cells. 2009 May . 27(5):1032-41. PubMed
Multipurpose modular lentiviral vectors for RNA interference and transgene expression. Kesireddy V, van der Ven PF, Furst DO. Mol Biol Rep. 2010 Jul;37(6):2863-70. doi: 10.1007/s11033-009-9840-8. Epub 2009 Oct 2. PubMed
Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR): implications for impaired post-transcriptional regulation of vascular endothelial growth factor. Lu L, Wang S, Zheng L, Li X, Suswam EA, Zhang X, Wheeler CG, Nabors LB, Filippova N, King PH. J Biol Chem. 2009 Dec 4. 284(49):33989-98. PubMed
Pharmacological and genetic accumulation of hypoxia-inducible factor-1alpha enhances excitatory synaptic transmission in hippocampal neurons through the production of vascular endothelial growth factor. Huang YF, Yang CH, Huang CC, Tai MH, Hsu KS. J Neurosci. 2010 Apr 28;30(17):6080-93. doi: 10.1523/JNEUROSCI.5493-09.2010. PubMed
Regulation of human bone marrow stromal cell proliferation and differentiation capacity by glucocorticoid receptor and AP-1 crosstalk. Carcamo-Orive I, Gaztelumendi A, Delgado J, Tejados N, Dorronsoro A, Fernandez-Rueda J, Pennington DJ, Trigueros C. J Bone Miner Res. 2010 Oct;25(10):2115-25. doi: 10.1002/jbmr.120. PubMed
PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons. Ning K, Drepper C, Valori CF, Ahsan M, Wyles M, Higginbottom A, Herrmann T, Shaw P, Azzouz M, Sendtner M. Hum Mol Genet. 2010 Aug 15;19(16):3159-68. doi: 10.1093/hmg/ddq226. Epub 2010 Jun 4. PubMed
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Jun JI, Lau LF. Nat Cell Biol. 2010 Jul;12(7):676-85. doi: 10.1038/ncb2070. Epub 2010 Jun 6. PubMed
Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis. Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo SW, Valori CF, Cox L, Sharrack B, Wharton SB, Ince PG, Shaw PJ, Azzouz M. Brain. 2011 Feb;134(Pt 2):506-17. doi: 10.1093/brain/awq345. Epub 2011 Jan 12. PubMed
Polypyrimidine tract-binding protein is critical for the turnover and subcellular distribution of CD40 ligand mRNA in CD4+ T cells. Matus-Nicodemos R, Vavassori S, Castro-Faix M, Valentin-Acevedo A, Singh K, Marcelli V, Covey LR. J Immunol. 2011 Feb 15;186(4):2164-71. doi: 10.4049/jimmunol.1003236. Epub 2011 Jan 17. PubMed
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C, Thompson J, Boue S, Fung HL, Sancho-Martinez I, Zhang K, Yates J 3rd, Izpisua Belmonte JC. Nature. 2011 Apr 14;472(7342):221-5. doi: 10.1038/nature09879. Epub 2011 Feb 23. PubMed
Somatic coding mutations in human induced pluripotent stem cells. Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, Rossi DJ, Thomson JA, Eggan K, Daley GQ, Goldstein LS, Zhang K. Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805. PubMed
The RNA-binding protein HuR promotes glioma growth and treatment resistance. Filippova N, Yang X, Wang Y, Gillespie GY, Langford C, King PH, Wheeler C, Nabors LB. Mol Cancer Res. 2011 May;9(5):648-59. doi: 10.1158/1541-7786.MCR-10-0325. Epub 2011 Apr 15. PubMed
Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection. Dick E, Matsa E, Young LE, Darling D, Denning C. Nat Protoc. 2011 Jun;6(6):701-14. doi: 10.1038/nprot.2011.320. Epub 2011 May 5. PubMed
Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways. Lee CC, Huang CC, Hsu KS. Neuropharmacology. 2011 Sep;61(4):867-79. doi: 10.1016/j.neuropharm.2011.06.003. Epub 2011 Jun 12. PubMed
The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. Kim JY, Oh MH, Bernard LP, Macara IG, Zhang H. J Biol Chem. 2011 Oct 28;286(43):37615-24. doi: 10.1074/jbc.M111.268029. Epub 2011 Sep 7. PubMed
The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53-p21 axis. Pelletier J, Dayan F, Durivault J, Ilc K, Pecou E, Pouyssegur J, Mazure NM. Oncogene. 2012 Jun 14;31(24):2989-3001. doi: 10.1038/onc.2011.471. Epub 2011 Oct 17. PubMed
FGF signalling inhibits neural induction in human embryonic stem cells. Greber B, Coulon P, Zhang M, Moritz S, Frank S, Muller-Molina AJ, Arauzo-Bravo MJ, Han DW, Pape HC, Scholer HR. EMBO J. 2011 Nov 15;30(24):4874-84. doi: 10.1038/emboj.2011.407. PubMed
Angiogenic properties of myofibroblasts isolated from normal human skin wounds. Mayrand D, Laforce-Lavoie A, Larochelle S, Langlois A, Genest H, Roy M, Moulin VJ. Angiogenesis. 2012 Jun;15(2):199-212. doi: 10.1007/s10456-012-9253-5. Epub 2012 Feb 18. PubMed
Polyamine-regulated translation of spermidine/spermine-N1-acetyltransferase. Perez-Leal O, Barrero CA, Clarkson AB, Casero RA Jr, Merali S. Mol Cell Biol. 2012 Apr;32(8):1453-67. doi: 10.1128/MCB.06444-11. Epub 2012 Feb 21. PubMed
Histone deacetylase 3 modulates the expansion of human hematopoietic stem cells. Elizalde C, Fernandez-Rueda J, Salcedo JM, Dorronsoro A, Ferrin I, Jakobsson E, Trigueros C. Stem Cells Dev. 2012 Sep 20;21(14):2581-91. doi: 10.1089/scd.2011.0698. Epub 2012 May 8. PubMed
IL1beta induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-kappaB. Carrero R, Cerrada I, Lledo E, Dopazo J, Garcia-Garcia F, Rubio MP, Trigueros C, Dorronsoro A, Ruiz-Sauri A, Montero JA, Sepulveda P. Stem Cell Rev. 2012 Sep;8(3):905-16. doi: 10.1007/s12015-012-9364-9. PubMed
Zfp296 is a novel, pluripotent-specific reprogramming factor. Fischedick G, Klein DC, Wu G, Esch D, Hoing S, Han DW, Reinhardt P, Hergarten K, Tapia N, Scholer HR, Sterneckert JL. PLoS One. 2012;7(4):e34645. doi: 10.1371/journal.pone.0034645. Epub 2012 Apr 2. PubMed
LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump. Fan S, Niu Y, Tan N, Wu Z, Wang Y, You H, Ke R, Song J, Shen Q, Wang W, Yao G, Shu H, Lin H, Yao M, Zhang Z, Gu J, Qin W. Oncogene. 2013 Mar 28;32(13):1682-90. doi: 10.1038/onc.2012.183. Epub 2012 May 14. PubMed
Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells. Galperin E, Abdelmoti L, Sorkin A. PLoS One. 2012;7(5):e36469. doi: 10.1371/journal.pone.0036469. Epub 2012 May 14. PubMed
A genome-wide analysis of lentivector integration sites using targeted sequence capture and next generation sequencing technology. Ustek D, Sirma S, Gumus E, Arikan M, Cakiris A, Abaci N, Mathew J, Emrence Z, Azakli H, Cosan F, Cakar A, Parlak M, Kursun O. Infect Genet Evol. 2012 Oct;12(7):1349-54. doi: 10.1016/j.meegid.2012.05.001. Epub 2012 May 14. PubMed
Human ESC self-renewal promoting microRNAs induce epithelial-mesenchymal transition in hepatocytes by controlling the PTEN and TGFbeta tumor suppressor signaling pathways. Jung CJ, Iyengar S, Blahnik KR, Jiang JX, Tahimic C, Torok NJ, de vere White RW, Farnham PJ, Zern M. Mol Cancer Res. 2012 Jul;10(7):979-91. doi: 10.1158/1541-7786.MCR-11-0421. Epub 2012 May 23. PubMed
Specific marking of hESCs-derived hematopoietic lineage by WAS-promoter driven lentiviral vectors. Munoz P, Toscano MG, Real PJ, Benabdellah K, Cobo M, Bueno C, Ramos-Mejia V, Menendez P, Anderson P, Martin F. PLoS One. 2012;7(6):e39091. doi: 10.1371/journal.pone.0039091. Epub 2012 Jun 14. PubMed
Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms. Nitta T, Lee S, Ha D, Arias M, Kozak CA, Fan H. Retrovirology. 2012 Jul 24;9:58. doi: 10.1186/1742-4690-9-58. PubMed
Mechanism of capsaicin receptor TRPV1-mediated toxicity in pain-sensing neurons focusing on the effects of Na(+)/Ca(2+) fluxes and the Ca(2+)-binding protein calretinin. Pecze L, Blum W, Schwaller B. Biochim Biophys Acta. 2013 Jul;1833(7):1680-91. doi: 10.1016/j.bbamcr.2012.08.018. Epub 2012 Sep 5. PubMed
Vascular endothelial growth factor-dependent spinogenesis underlies antidepressant-like effects of enriched environment. Huang YF, Yang CH, Huang CC, Hsu KS. J Biol Chem. 2012 Nov 30;287(49):40938-55. doi: 10.1074/jbc.M112.392076. Epub 2012 Oct 16. PubMed
Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting. Hertz MI, Landry DM, Willis AE, Luo G, Thompson SR. Mol Cell Biol. 2013 Mar;33(5):1016-26. doi: 10.1128/MCB.00879-12. Epub 2012 Dec 28. PubMed
Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming. Ruiz S, Gore A, Li Z, Panopoulos AD, Montserrat N, Fung HL, Giorgetti A, Bilic J, Batchelder EM, Zaehres H, Scholer HR, Zhang K, Izpisua Belmonte JC. Nat Commun. 2013;4:1382. doi: 10.1038/ncomms2381. PubMed
OLA1 protects cells in heat shock by stabilizing HSP70. Mao RF, Rubio V, Chen H, Bai L, Mansour OC, Shi ZZ. Cell Death Dis. 2013 Feb 14;4:e491. doi: 10.1038/cddis.2013.23. PubMed
Genetic manipulation of keratinocyte stem cells with lentiviral vectors. Yasuda M, Claypool DJ, Guevara E, Roop DR, Chen J. Methods Mol Biol. 2013;989:143-51. doi: 10.1007/978-1-62703-330-5_12. PubMed
Macrohistone variants preserve cell identity by preventing the gain of H3K4me2 during reprogramming to pluripotency. Barrero MJ, Sese B, Kuebler B, Bilic J, Boue S, Marti M, Izpisua Belmonte JC. Cell Rep. 2013 Apr 25;3(4):1005-11. doi: 10.1016/j.celrep.2013.02.029. Epub 2013 Mar 28. PubMed
Calretinin is essential for mesothelioma cell growth/survival in vitro: a potential new target for malignant mesothelioma therapy? Blum W, Schwaller B. Int J Cancer. 2013 Nov;133(9):2077-88. doi: 10.1002/ijc.28218. Epub 2013 Jul 9. PubMed
Translational control of Nrf2 within the open reading frame. Perez-Leal O, Barrero CA, Merali S. Biochem Biophys Res Commun. 2013 Jul 19;437(1):134-9. doi: 10.1016/j.bbrc.2013.06.052. Epub 2013 Jun 24. PubMed
SMYD2 is induced during cell differentiation and participates in early development. Sese B, Barrero MJ, Fabregat MC, Sander V, Izpisua Belmonte JC. Int J Dev Biol. 2013;57(5):357-64. doi: 10.1387/ijdb.130051ji. PubMed
Identification of epithelial stromal interaction 1 as a novel effector downstream of Kruppel-like factor 8 in breast cancer invasion and metastasis. Li T, Lu H, Shen C, Lahiri SK, Wason MS, Mukherjee D, Yu L, Zhao J. Oncogene. 2014 Sep 25;33(39):4746-55. doi: 10.1038/onc.2013.415. Epub 2013 Oct 7. PubMed
Doxycycline-regulated GDNF expression promotes axonal regeneration and functional recovery in transected peripheral nerve. Shakhbazau A, Mohanty C, Shcharbin D, Bryszewska M, Caminade AM, Majoral JP, Alant J, Midha R. J Control Release. 2013 Dec 28;172(3):841-51. doi: 10.1016/j.jconrel.2013.10.004. Epub 2013 Oct 17. PubMed
Adherens junction formation inhibits lentivirus entry and gene transfer. Padmashali R, You H, Karnik N, Lei P, Andreadis ST. PLoS One. 2013 Nov 13;8(11):e79265. doi: 10.1371/journal.pone.0079265. eCollection 2013. PubMed
The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling. Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, Bovijn C, Tavernier J, Peelman F. J Biol Chem. 2014 Jan 17;289(3):1364-76. doi: 10.1074/jbc.M113.499194. Epub 2013 Dec 2. PubMed
Human mesenchymal stromal cells modulate T-cell responses through TNF-alpha-mediated activation of NF-kappaB. Dorronsoro A, Ferrin I, Salcedo JM, Jakobsson E, Fernandez-Rueda J, Lang V, Sepulveda P, Fechter K, Pennington D, Trigueros C. Eur J Immunol. 2014 Feb;44(2):480-8. doi: 10.1002/eji.201343668. Epub 2013 Dec 4. PubMed
Identification of the NF-kappaB inhibitor A20 as a key regulator for human adipogenesis. Dorronsoro A, Lang V, Jakobsson E, Ferrin I, Salcedo JM, Fernandez-Rueda J, Fechter K, Rodriguez MS, Trigueros C. Cell Death Dis. 2013 Dec 19;4:e972. doi: 10.1038/cddis.2013.494. PubMed
Visualizing of signaling proteins on endosomes utilizing knockdown and reconstitution approach. Jeoung M, Galperin E. Methods Enzymol. 2014;534:47-63. doi: 10.1016/B978-0-12-397926-1.00003-2. PubMed
Rapid identification of regulatory microRNAs by miTRAP (miRNA trapping by RNA in vitro affinity purification). Braun J, Misiak D, Busch B, Krohn K, Huttelmaier S. Nucleic Acids Res. 2014 Apr;42(8):e66. doi: 10.1093/nar/gku127. Epub 2014 Feb 7. PubMed
PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons. Yang DJ, Wang XL, Ismail A, Ashman CJ, Valori CF, Wang G, Gao S, Higginbottom A, Ince PG, Azzouz M, Xu J, Shaw PJ, Ning K. Cell Death Dis. 2014 Feb 27;5:e1096. doi: 10.1038/cddis.2014.55. PubMed
Counteracting activities of OCT4 and KLF4 during reprogramming to pluripotency. Tiemann U, Marthaler AG, Adachi K, Wu G, Fischedick GU, Arauzo-Bravo MJ, Scholer HR, Tapia N. Stem Cell Reports. 2014 Feb 20;2(3):351-65. doi: 10.1016/j.stemcr.2014.01.005. eCollection 2014 Mar 11. PubMed
Overexpression of EMMPRIN isoform 2 is associated with head and neck cancer metastasis. Huang Z, Tan N, Guo W, Wang L, Li H, Zhang T, Liu X, Xu Q, Li J, Guo Z. PLoS One. 2014 Apr 4;9(4):e91596. doi: 10.1371/journal.pone.0091596. eCollection 2014. PubMed
Aligned collagen-GAG matrix as a 3D substrate for Schwann cell migration and dendrimer-based gene delivery. Shakhbazau A, Archibald SJ, Shcharbin D, Bryszewska M, Midha R. J Mater Sci Mater Med. 2014 Aug;25(8):1979-89. doi: 10.1007/s10856-014-5224-2. Epub 2014 May 7. PubMed
Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space. Pruessmeyer J, Hess FM, Alert H, Groth E, Pasqualon T, Schwarz N, Nyamoya S, Kollert J, van der Vorst E, Donners M, Martin C, Uhlig S, Saftig P, Dreymueller D, Ludwig A. Blood. 2014 Jun 26;123(26):4077-88. doi: 10.1182/blood-2013-09-511543. Epub 2014 May 15. PubMed
Presynaptic clathrin levels are a limiting factor for synaptic transmission. Lopez-Murcia FJ, Royle SJ, Llobet A. J Neurosci. 2014 Jun 18;34(25):8618-29. doi: 10.1523/JNEUROSCI.5081-13.2014. PubMed
Human somatic cell mutagenesis creates genetically tractable sarcomas. Molyneux SD, Waterhouse PD, Shelton D, Shao YW, Watling CM, Tang QL, Harris IS, Dickson BC, Tharmapalan P, Sandve GK, Zhang X, Bailey SD, Berman H, Wunder JS, Izsvak Z, Lupien M, Mak TW, Khokha R. Nat Genet. 2014 Sep;46(9):964-72. doi: 10.1038/ng.3065. Epub 2014 Aug 17. PubMed
MYCN-dependent expression of sulfatase-2 regulates neuroblastoma cell survival. Solari V, Borriello L, Turcatel G, Shimada H, Sposto R, Fernandez GE, Asgharzadeh S, Yates EA, Turnbull JE, DeClerck YA. Cancer Res. 2014 Nov 1;74(21):5999-6009. doi: 10.1158/0008-5472.CAN-13-2513. Epub 2014 Aug 27. PubMed
Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis. Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H. Nat Commun. 2014 Sep 11;5:4839. doi: 10.1038/ncomms5839. PubMed
Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells. Zheng Q, Cai X, Tan MH, Schaffert S, Arnold CP, Gong X, Chen CZ, Huang S. Biotechniques. 2014 Sep 1;57(3):115-24. doi: 10.2144/000114196. eCollection 2014. PubMed

Associated Plasmids

CERS2 suppresses tumor cell invasion and is associated with decreased V-ATPase and MMP-2/MMP-9 activities in breast cancer. Fan SH, Wang YY, Lu J, Zheng YL, Wu DM, Zhang ZF, Shan Q, Hu B, Li MQ, Cheng W. J Cell Biochem. 2015 Apr;116(4):502-13. doi: 10.1002/jcb.24978. PubMed
Cartilage repair using human embryonic stem cell-derived chondroprogenitors. Cheng A, Kapacee Z, Peng J, Lu S, Lucas RJ, Hardingham TE, Kimber SJ. Stem Cells Transl Med. 2014 Nov;3(11):1287-94. doi: 10.5966/sctm.2014-0101. Epub 2014 Oct 1. PubMed
Universal real-time PCR-based assay for lentiviral titration. Barczak W, Suchorska W, Rubis B, Kulcenty K. Mol Biotechnol. 2015 Feb;57(2):195-200. doi: 10.1007/s12033-014-9815-4. PubMed
Characterization and modeling of Ca(2+) oscillations in mouse primary mesothelial cells. Pecze L, Schwaller B. Biochim Biophys Acta. 2015 Mar;1854(3):632-45. doi: 10.1016/j.bbamcr.2014.12.025. Epub 2014 Dec 30. PubMed
CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCgamma1 activation: evidence from mice and humans. Martinez-Torres AC, Quiney C, Attout T, Boullet H, Herbi L, Vela L, Barbier S, Chateau D, Chapiro E, Nguyen-Khac F, Davi F, Le Garff-Tavernier M, Moumne R, Sarfati M, Karoyan P, Merle-Beral H, Launay P, Susin SA. PLoS Med. 2015 Mar 3;12(3):e1001796. doi: 10.1371/journal.pmed.1001796. eCollection 2015 Mar. PubMed
Alpha-catenin-dependent recruitment of the centrosomal protein CAP350 to adherens junctions allows epithelial cells to acquire a columnar shape. Gavilan MP, Arjona M, Zurbano A, Formstecher E, Martinez-Morales JR, Bornens M, Rios RM. PLoS Biol. 2015 Mar 12;13(3):e1002087. doi: 10.1371/journal.pbio.1002087. eCollection 2015 Mar. PubMed
Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity. Baschieri F, Uetz-von Allmen E, Legler DF, Farhan H. Cell Cycle. 2015;14(8):1139-47. doi: 10.1080/15384101.2015.1007771. PubMed
MicroRNA-200c-141 and Np63 are required for breast epithelial differentiation and branching morphogenesis. Hilmarsdottir B, Briem E, Sigurdsson V, Franzdottir SR, Ringner M, Arason AJ, Bergthorsson JT, Magnusson MK, Gudjonsson T. Dev Biol. 2015 Jul 15;403(2):150-61. doi: 10.1016/j.ydbio.2015.05.007. Epub 2015 May 9. PubMed
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap. Nurnberg ST, Cheng K, Raiesdana A, Kundu R, Miller CL, Kim JB, Arora K, Carcamo-Oribe I, Xiong Y, Tellakula N, Nanda V, Murthy N, Boisvert WA, Hedin U, Perisic L, Aldi S, Maegdefessel L, Pjanic M, Owens GK, Tallquist MD, Quertermous T. PLoS Genet. 2015 May 28;11(5):e1005155. doi: 10.1371/journal.pgen.1005155. eCollection 2015 May. PubMed
Use of Ferritin Expression, Regulated by Neural Cell-Specific Promoters in Human Adipose Tissue-Derived Mesenchymal Stem Cells, to Monitor Differentiation with Magnetic Resonance Imaging In Vitro. Song C, Wang J, Mo C, Mu S, Jiang X, Li X, Zhong S, Zhao Z, Zhou G. PLoS One. 2015 Jul 15;10(7):e0132480. doi: 10.1371/journal.pone.0132480. eCollection 2015. PubMed
Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models. Aime P, Sun X, Zareen N, Rao A, Berman Z, Volpicelli-Daley L, Bernd P, Crary JF, Levy OA, Greene LA. J Neurosci. 2015 Jul 29;35(30):10731-49. doi: 10.1523/JNEUROSCI.0614-15.2015. PubMed
CFTR inactivation by lentiviral vector-mediated RNA interference and CRISPR-Cas9 genome editing in human airway epithelial cells. Bellec J, Bacchetta M, Losa D, Anegon I, Chanson M, Nguyen TH. Curr Gene Ther. 2015;15(5):447-59. PubMed
OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation. Chen H, Song R, Wang G, Ding Z, Yang C, Zhang J, Zeng Z, Rubio V, Wang L, Zu N, Weiskoff AM, Minze LJ, Jeyabal PV, Mansour OC, Bai L, Merrick WC, Zheng S, Shi ZZ. Sci Rep. 2015 Aug 18;5:13241. doi: 10.1038/srep13241. PubMed
The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated beta-catenin by sequestering TCF4 to the nuclear membrane. Loregger A, Grandl M, Mejias-Luque R, Allgauer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M. Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757. PubMed
Routes of Ca2+ Shuttling during Ca2+ Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca2+ HANDLING AND CYTOSOLIC Ca2+ BUFFERS. Pecze L, Blum W, Schwaller B. J Biol Chem. 2015 Nov 20;290(47):28214-30. doi: 10.1074/jbc.M115.663179. Epub 2015 Sep 22. PubMed
OTX2 is a therapeutic target for retinoblastoma and may function as a common factor between C-MYC, CRX, and phosphorylated RB pathways. Li J, Di C, Jing J, Di Q, Nakhla J, Adamson DC. Int J Oncol. 2015 Nov;47(5):1703-10. doi: 10.3892/ijo.2015.3179. Epub 2015 Sep 23. PubMed
Hydrogel biophysical properties instruct coculture-mediated osteogenic potential. Murphy KC, Stilhano RS, Mitra D, Zhou D, Batarni S, Silva EA, Leach JK. FASEB J. 2016 Jan;30(1):477-86. doi: 10.1096/fj.15-279984. Epub 2015 Oct 6. PubMed
Antagonistic Regulation of Parvalbumin Expression and Mitochondrial Calcium Handling Capacity in Renal Epithelial Cells. Henzi T, Schwaller B. PLoS One. 2015 Nov 5;10(11):e0142005. doi: 10.1371/journal.pone.0142005. eCollection 2015. PubMed
The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Kessler M, Hoffmann K, Brinkmann V, Thieck O, Jackisch S, Toelle B, Berger H, Mollenkopf HJ, Mangler M, Sehouli J, Fotopoulou C, Meyer TF. Nat Commun. 2015 Dec 8;6:8989. doi: 10.1038/ncomms9989. PubMed
Overexpression or absence of calretinin in mouse primary mesothelial cells inversely affects proliferation and cell migration. Blum W, Pecze L, Felley-Bosco E, Schwaller B. Respir Res. 2015 Dec 22;16:153. doi: 10.1186/s12931-015-0311-6. PubMed
Inhibition of Canonical NF-kappaB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction. Vincendeau M, Hadian K, Messias AC, Brenke JK, Halander J, Griesbach R, Greczmiel U, Bertossi A, Stehle R, Nagel D, Demski K, Velvarska H, Niessing D, Geerlof A, Sattler M, Krappmann D. Sci Rep. 2016 Jan 7;6:18934. doi: 10.1038/srep18934. PubMed
Oncogenic CARMA1 couples NF-kappaB and beta-catenin signaling in diffuse large B-cell lymphomas. Bognar MK, Vincendeau M, Erdmann T, Seeholzer T, Grau M, Linnemann JR, Ruland J, Scheel CH, Lenz P, Ott G, Lenz G, Hauck SM, Krappmann D. Oncogene. 2016 Jan 18. doi: 10.1038/onc.2015.493. PubMed
Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma. Puujalka E, Heinz M, Hoesel B, Friedl P, Schweighofer B, Wenzina J, Pirker C, Schmid JA, Loewe R, Wagner EF, Berger W, Petzelbauer P. J Invest Dermatol. 2016 May;136(5):967-77. doi: 10.1016/j.jid.2016.01.020. Epub 2016 Jan 30. PubMed
Effects of Plectin Depletion on Keratin Network Dynamics and Organization. Moch M, Windoffer R, Schwarz N, Pohl R, Omenzetter A, Schnakenberg U, Herb F, Chaisaowong K, Merhof D, Ramms L, Fabris G, Hoffmann B, Merkel R, Leube RE. PLoS One. 2016 Mar 23;11(3):e0149106. doi: 10.1371/journal.pone.0149106. eCollection 2016. PubMed
SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation. Duncan MT, DeLuca TA, Kuo HY, Yi M, Mrksich M, Miller WM. Exp Cell Res. 2016 May 15;344(1):40-52. doi: 10.1016/j.yexcr.2016.04.010. Epub 2016 Apr 13. PubMed
Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation. McDonald JI, Celik H, Rois LE, Fishberger G, Fowler T, Rees R, Kramer A, Martens A, Edwards JR, Challen GA. Biol Open. 2016 May 11. pii: bio.019067. doi: 10.1242/bio.019067. PubMed

Associated Plasmids

VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation. Brinkmann BF, Steinbacher T, Hartmann C, Kummer D, Pajonczyk D, Mirzapourshafiyi F, Nakayama M, Weide T, Gerke V, Ebnet K. Mol Biol Cell. 2016 Sep 15;27(18):2811-21. doi: 10.1091/mbc.E16-02-0127. Epub 2016 Jul 27. PubMed
Deregulation of the Hippo pathway in mouse mammary stem cells promotes mammary tumorigenesis. Li H, Gumbiner BM. Mamm Genome. 2016 Dec;27(11-12):556-564. Epub 2016 Sep 6. PubMed
Endogenous TRPV1 stimulation leads to the activation of the inositol phospholipid pathway necessary for sustained Ca2+ oscillations. Pecze L, Blum W, Henzi T, Schwaller B. Biochim Biophys Acta. 2016 Dec;1863(12):2905-2915. doi: 10.1016/j.bbamcr.2016.09.013. Epub 2016 Sep 20. PubMed
Complementary Roles of Estrogen-Related Receptors in Brown Adipocyte Thermogenic Function. Gantner ML, Hazen BC, Eury E, Brown EL, Kralli A. Endocrinology. 2016 Dec;157(12):4770-4781. Epub 2016 Oct 20. PubMed
Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells. Benabdellah K, Munoz P, Cobo M, Gutierrez-Guerrero A, Sanchez-Hernandez S, Garcia-Perez A, Anderson P, Carrillo-Galvez AB, Toscano MG, Martin F. Sci Rep. 2016 Nov 17;6:37289. doi: 10.1038/srep37289. PubMed
The STAT3-miRNA-92-Wnt Signaling Pathway Regulates Spheroid Formation and Malignant Progression in Ovarian Cancer. Chen MW, Yang ST, Chien MH, Hua KT, Wu CJ, Hsiao SM, Lin H, Hsiao M, Su JL, Wei LH. Cancer Res. 2017 Apr 15;77(8):1955-1967. doi: 10.1158/0008-5472.CAN-16-1115. Epub 2017 Feb 16. PubMed
YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-kappaB. Schimmack G, Schorpp K, Kutzner K, Gehring T, Brenke JK, Hadian K, Krappmann D. Elife. 2017 Feb 28;6. pii: e22416. doi: 10.7554/eLife.22416. PubMed
GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Yamasaki T, Hoyos-Ramirez E, Martenson JS, Morimoto-Tomita M, Tomita S. Neuron. 2017 Mar 8;93(5):1138-1152.e6. doi: 10.1016/j.neuron.2017.02.023. PubMed
Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions. Zhang C, Jiang H, Wang P, Liu H, Sun X. Sci Rep. 2017 Mar 20;7:44708. doi: 10.1038/srep44708. PubMed
Association of Cardiac Galectin-3 Expression, Myocarditis, and Fibrosis in Chronic Chagas Disease Cardiomyopathy. Souza BSF, Silva DN, Carvalho RH, Sampaio GLA, Paredes BD, Aragao Franca L, Azevedo CM, Vasconcelos JF, Meira CS, Neto PC, Macambira SG, da Silva KN, Allahdadi KJ, Tavora F, de Souza Neto JD, Dos Santos RR, Soares MBP. Am J Pathol. 2017 May;187(5):1134-1146. doi: 10.1016/j.ajpath.2017.01.016. Epub 2017 Mar 17. PubMed
The metalloproteinase ADAM8 promotes leukocyte recruitment in vitro and in acute lung inflammation. Dreymueller D, Pruessmeyer J, Schumacher J, Fellendorf S, Hess FM, Seifert A, Babendreyer A, Bartsch JW, Ludwig A. Am J Physiol Lung Cell Mol Physiol. 2017 Jun 8:ajplung.00444.2016. doi: 10.1152/ajplung.00444.2016. PubMed
Absolute measurement of gene transcripts with Selfie-digital PCR. Podlesniy P, Trullas R. Sci Rep. 2017 Aug 21;7(1):8328. doi: 10.1038/s41598-017-08270-w. PubMed
Modulation of hippocampal synapse maturation by activity-regulated E3 ligase via non-canonical pathway. Kumari P, Srinivasan B, Banerjee S. Neuroscience. 2017 Nov 19;364:226-241. doi: 10.1016/j.neuroscience.2017.08.057. Epub 2017 Sep 8. PubMed
ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells. Conrad C, Gotte M, Schlomann U, Roessler M, Pagenstecher A, Anderson P, Preston J, Pruessmeyer J, Ludwig A, Li R, Kamm RD, Ritz R, Carl B, Nimsky C, Bartsch JW. Int J Cancer. 2018 Feb 15;142(4):779-791. doi: 10.1002/ijc.31090. Epub 2017 Oct 31. PubMed
Biological noise and positional effects influence cell stemness. Blum W, Henzi T, Schwaller B, Pecze L. J Biol Chem. 2018 Apr 6;293(14):5247-5258. doi: 10.1074/jbc.RA117.001643. Epub 2018 Feb 12. PubMed
hTERT gene knockdown enhances response to radio- and chemotherapy in head and neck cancer cell lines through a DNA damage pathway modification. Barczak W, Sobecka A, Golusinski P, Masternak MM, Rubis B, Suchorska WM, Golusinski W. Sci Rep. 2018 Apr 13;8(1):5949. doi: 10.1038/s41598-018-24503-y. PubMed
Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7. Fang J, Yang J, Wu X, Zhang G, Li T, Wang X, Zhang H, Wang CC, Liu GH, Wang L. Aging Cell. 2018 Apr 16:e12765. doi: 10.1111/acel.12765. PubMed
Regulation of calretinin in malignant mesothelioma is mediated by septin 7 binding to the CALB2 promoter. Blum W, Pecze L, Rodriguez JW, Steinauer M, Schwaller B. BMC Cancer. 2018 Apr 27;18(1):475. doi: 10.1186/s12885-018-4385-7. PubMed
Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds. Huynh NPT, Brunger JM, Gloss CC, Moutos FT, Gersbach CA, Guilak F. Tissue Eng Part A. 2018 Oct;24(19-20):1531-1544. doi: 10.1089/ten.TEA.2017.0510. Epub 2018 Jul 13. PubMed
Regulation of BDNF Release by ARMS/Kidins220 through Modulation of Synaptotagmin-IV Levels. Lopez-Benito S, Sanchez-Sanchez J, Brito V, Calvo L, Lisa S, Torres-Valle M, Palko ME, Vicente-Garcia C, Fernandez-Fernandez S, Bolanos JP, Gines S, Tessarollo L, Arevalo JC. J Neurosci. 2018 Jun 6;38(23):5415-5428. doi: 10.1523/JNEUROSCI.1653-17.2018. Epub 2018 May 16. PubMed
Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry. Schatzle P, Esteves da Silva M, Tas RP, Katrukha EA, Hu HY, Wierenga CJ, Kapitein LC, Hoogenraad CC. Curr Biol. 2018 Jul 9;28(13):2081-2093.e6. doi: 10.1016/j.cub.2018.05.004. Epub 2018 Jun 14. PubMed
Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue. Torres P, Ramirez-Nunez O, Romero-Guevara R, Bares G, Granado-Serrano AB, Ayala V, Boada J, Fontdevila L, Povedano M, Sanchis D, Pamplona R, Ferrer I, Portero-Otin M. Autophagy. 2018;14(8):1398-1403. doi: 10.1080/15548627.2018.1474311. Epub 2018 Jul 28. PubMed
Inactivation of Citron Kinase Inhibits Medulloblastoma Progression by Inducing Apoptosis and Cell Senescence. Pallavicini G, Sgro F, Garello F, Falcone M, Bitonto V, Berto GE, Bianchi FT, Gai M, Chiotto AMA, Filippi M, Cutrin JC, Ala U, Terreno E, Turco E, Cunto FD. Cancer Res. 2018 Aug 15;78(16):4599-4612. doi: 10.1158/0008-5472.CAN-17-4060. Epub 2018 Jun 19. PubMed
Meta-Analysis of Autoimmune Regulator-Regulated Genes in Human and Murine Models: A Novel Human Model Provides Insights on the Role of Autoimmune Regulator in Regulating STAT1 and STAT1-Regulated Genes. Lovewell TRJ, McDonagh AJG, Messenger AG, Azzouz M, Tazi-Ahnini R. Front Immunol. 2018 Jun 28;9:1380. doi: 10.3389/fimmu.2018.01380. eCollection 2018. PubMed
Vesicular stomatitis virus G protein transmembrane region is crucial for the hemi-fusion to full fusion transition. Ci Y, Yang Y, Xu C, Shi L. Sci Rep. 2018 Jul 13;8(1):10669. doi: 10.1038/s41598-018-28868-y. PubMed
SIRT6 deficiency results in developmental retardation in cynomolgus monkeys. Zhang W, Wan H, Feng G, Qu J, Wang J, Jing Y, Ren R, Liu Z, Zhang L, Chen Z, Wang S, Zhao Y, Wang Z, Yuan Y, Zhou Q, Li W, Liu GH, Hu B. Nature. 2018 Aug;560(7720):661-665. doi: 10.1038/s41586-018-0437-z. Epub 2018 Aug 22. PubMed
Parvalbumin alters mitochondrial dynamics and affects cell morphology. Lichvarova L, Henzi T, Safiulina D, Kaasik A, Schwaller B. Cell Mol Life Sci. 2018 Dec;75(24):4643-4666. doi: 10.1007/s00018-018-2921-x. Epub 2018 Sep 25. PubMed
Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis. Wu X, Zhang L, Miao Y, Yang J, Wang X, Wang CC, Feng J, Wang L. Redox Biol. 2019 Jan;20:46-59. doi: 10.1016/j.redox.2018.09.021. Epub 2018 Sep 26. PubMed
Integrin-Rac signalling for mammary epithelial stem cell self-renewal. Olabi S, Ucar A, Brennan K, Streuli CH. Breast Cancer Res. 2018 Oct 22;20(1):128. doi: 10.1186/s13058-018-1048-1. PubMed
Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells. Neumeyer V, Grandl M, Dietl A, Brutau-Abia A, Allgauer M, Kalali B, Zhang Y, Pan KF, Steiger K, Vieth M, Anton M, Mejias-Luque R, Gerhard M. Carcinogenesis. 2018 Oct 31. pii: 5149556. doi: 10.1093/carcin/bgy152. PubMed
Calretinin Functions in Malignant Mesothelioma Cells Cannot Be Replaced by the Closely Related Ca(2+)-Binding Proteins Calbindin-D28k and Parvalbumin. Worthmuller J, Oberson A, Salicio V, Blum W, Schwaller B. Int J Mol Sci. 2018 Dec 12;19(12). pii: ijms19124015. doi: 10.3390/ijms19124015. PubMed
FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. Yan P, Li Q, Wang L, Lu P, Suzuki K, Liu Z, Lei J, Li W, He X, Wang S, Ding J, Chan P, Zhang W, Song M, Izpisua Belmonte JC, Qu J, Tang F, Liu GH. Cell Stem Cell. 2019 Mar 7;24(3):447-461.e8. doi: 10.1016/j.stem.2018.12.002. Epub 2019 Jan 17. PubMed
Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. Ren X, Hu B, Song M, Ding Z, Dang Y, Liu Z, Zhang W, Ji Q, Ren R, Ding J, Chan P, Jiang C, Ye K, Qu J, Tang F, Liu GH. Cell Rep. 2019 Mar 26;26(13):3643-3656.e7. doi: 10.1016/j.celrep.2019.02.088. PubMed
Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis. Fu L, Hu Y, Song M, Liu Z, Zhang W, Yu FX, Wu J, Wang S, Izpisua Belmonte JC, Chan P, Qu J, Tang F, Liu GH. PLoS Biol. 2019 Apr 1;17(4):e3000201. doi: 10.1371/journal.pbio.3000201. eCollection 2019 Apr. PubMed
OCT4 and PAX6 determine the dual function of SOX2 in human ESCs as a key pluripotent or neural factor. Zhang S, Bell E, Zhi H, Brown S, Imran SAM, Azuara V, Cui W. Stem Cell Res Ther. 2019 Apr 18;10(1):122. doi: 10.1186/s13287-019-1228-7. PubMed
Slc25a36 modulates pluripotency of mouse embryonic stem cells by regulating mitochondrial function and glutathione level. Xin Y, Wang Y, Zhong L, Shi B, Liang H, Han J. Biochem J. 2019 Jun 11;476(11):1585-1604. doi: 10.1042/BCJ20190057. PubMed
Genetic Modification of Human Primary Keratinocytes by Lentiviral Vectors. Freije A, Sanz-Gomez N, Gandarillas A. Methods Mol Biol. 2019 May 24. doi: 10.1007/7651_2019_238. PubMed
MIR148A family regulates cardiomyocyte differentiation of human embryonic stem cells by inhibiting the DLL1-mediated NOTCH signaling pathway. Fang X, Miao S, Yu Y, Ding F, Han X, Wu H, Zhao ZA, Wang Y, Hu S, Lei W. J Mol Cell Cardiol. 2019 Jun 22;134:1-12. doi: 10.1016/j.yjmcc.2019.06.014. PubMed
microRNA-126 Is a Tumor Suppressor of Granulosa Cell Tumor Mediated by Its Host Gene EGFL7. Tu J, Cheung HH, Lu G, Chan CL, Chen Z, Chan WY. Front Oncol. 2019 Jun 11;9:486. doi: 10.3389/fonc.2019.00486. eCollection 2019. PubMed
A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells. Olbrich T, Vega-Sendino M, Murga M, de Carcer G, Malumbres M, Ortega S, Ruiz S, Fernandez-Capetillo O. Cell Rep. 2019 Jul 16;28(3):597-604.e4. doi: 10.1016/j.celrep.2019.06.060. PubMed
Parvalbumin expression in oligodendrocyte-like CG4 cells causes a reduction in mitochondrial volume, attenuation in reactive oxygen species production and a decrease in cell processes' length and branching. Lichvarova L, Blum W, Schwaller B, Szabolcsi V. Sci Rep. 2019 Jul 22;9(1):10603. doi: 10.1038/s41598-019-47112-9. PubMed
FA-SAT ncRNA interacts with PKM2 protein: depletion of this complex induces a switch from cell proliferation to apoptosis. Ferreira D, Escudeiro A, Adega F, Anjo SI, Manadas B, Chaves R. Cell Mol Life Sci. 2020 Apr;77(7):1371-1386. doi: 10.1007/s00018-019-03234-x. Epub 2019 Jul 25. PubMed
Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area. Zhao R, Afthinos A, Zhu T, Mistriotis P, Li Y, Serra SA, Zhang Y, Yankaskas CL, He S, Valverde MA, Sun SX, Konstantopoulos K. Sci Adv. 2019 Jul 24;5(7):eaaw7243. doi: 10.1126/sciadv.aaw7243. eCollection 2019 Jul. PubMed
Modulation of Calretinin Expression in Human Mesothelioma Cells Reveals the Implication of the FAK and Wnt Signaling Pathways in Conferring Chemoresistance towards Cisplatin. Worthmuller J, Salicio V, Oberson A, Blum W, Schwaller B. Int J Mol Sci. 2019 Oct 29;20(21). pii: ijms20215391. doi: 10.3390/ijms20215391. PubMed
BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium. Gambardella L, McManus SA, Moignard V, Sebukhan D, Delaune A, Andrews S, Bernard WG, Morrison MA, Riley PR, Gottgens B, Gambardella Le Novere N, Sinha S. Development. 2019 Dec 13;146(24). pii: dev.174441. doi: 10.1242/dev.174441. PubMed
The phytohormone forchlorfenuron decreases viability and proliferation of malignant mesothelioma cells in vitro and in vivo. Blum W, Henzi T, Pecze L, Diep KL, Bochet CG, Schwaller B. Oncotarget. 2019 Dec 10;10(65):6944-6956. doi: 10.18632/oncotarget.27341. eCollection 2019 Dec 10. PubMed
Silica-Polymer Composites as the Novel Antibiotic Delivery Systems for Bone Tissue Infection. Skwira A, Szewczyk A, Konopacka A, Gorska M, Majda D, Sadej R, Prokopowicz M. Pharmaceutics. 2019 Dec 30;12(1). pii: pharmaceutics12010028. doi: 10.3390/pharmaceutics12010028. PubMed
Outside-in regulation of the readily releasable pool of synaptic vesicles by alpha2delta-1. Martinez San Segundo P, Terni B, Burgueno J, Monroy X, Dordal A, Merlos M, Llobet A. FASEB J. 2020 Jan;34(1):1362-1377. doi: 10.1096/fj.201901551R. Epub 2019 Nov 30. PubMed
Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging. Ma S, Sun S, Geng L, Song M, Wang W, Ye Y, Ji Q, Zou Z, Wang S, He X, Li W, Esteban CR, Long X, Guo G, Chan P, Zhou Q, Belmonte JCI, Zhang W, Qu J, Liu GH. Cell. 2020 Mar 5;180(5):984-1001.e22. doi: 10.1016/j.cell.2020.02.008. Epub 2020 Feb 27. PubMed
Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia. He BL, Yang N, Man CH, Ng NK, Cher CY, Leung HC, Kan LL, Cheng BY, Lam SS, Wang ML, Zhang CX, Kwok H, Cheng G, Sharma R, Ma AC, So CW, Kwong YL, Leung AY. EMBO Mol Med. 2020 Apr 7;12(4):e10895. doi: 10.15252/emmm.201910895. Epub 2020 Mar 5. PubMed
Histone H1 eviction by the histone chaperone SET reduces cell survival following DNA damage. Mandemaker IK, Zhou D, Bruens ST, Dekkers DH, Verschure PJ, Edupuganti RR, Meshorer E, Demmers JAA, Marteijn JA. J Cell Sci. 2020 May 11;133(9). pii: jcs.235473. doi: 10.1242/jcs.235473. PubMed
Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway. Huynh NP, Gloss CC, Lorentz J, Tang R, Brunger JM, McAlinden A, Zhang B, Guilak F. Elife. 2020 Mar 23;9. pii: 49558. doi: 10.7554/eLife.49558. PubMed
Genetic correction of Werner syndrome gene reveals impaired pro-angiogenic function and HGF insufficiency in mesenchymal stem cells. Tu J, Wan C, Zhang F, Cao L, Law PWN, Tian Y, Lu G, Rennert OM, Chan WY, Cheung HH. Aging Cell. 2020 May;19(5):e13116. doi: 10.1111/acel.13116. Epub 2020 Apr 22. PubMed
SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer. Bi S, Liu Z, Wu Z, Wang Z, Liu X, Wang S, Ren J, Yao Y, Zhang W, Song M, Liu GH, Qu J. Protein Cell. 2020 Jul;11(7):483-504. doi: 10.1007/s13238-020-00728-4. Epub 2020 Jun 6. PubMed
Dorsoventral polarity directs cell responses to migration track geometries. Wisniewski EO, Mistriotis P, Bera K, Law RA, Zhang J, Nikolic M, Weiger M, Parlani M, Tuntithavornwat S, Afthinos A, Zhao R, Wirtz D, Kalab P, Scarcelli G, Friedl P, Konstantopoulos K. Sci Adv. 2020 Jul 31;6(31):eaba6505. doi: 10.1126/sciadv.aba6505. eCollection 2020 Jul. PubMed
Long non-coding RNA GHET1/miR-105/RAP2B axis regulates the progression of acute myeloid leukemia. Xiao Y, Li T, Xue Q, Miao L. J Cancer. 2020 Oct 17;11(23):7081-7090. doi: 10.7150/jca.47294. eCollection 2020. PubMed
IRF-1 expressed in the inner cell mass of the porcine early blastocyst enhances the pluripotency of induced pluripotent stem cells. Shi B, Gao D, Zhong L, Zhi M, Weng X, Xu J, Li J, Du X, Xin Y, Gao J, Zhu Q, Cao S, Liu Z, Han J. Stem Cell Res Ther. 2020 Nov 27;11(1):505. doi: 10.1186/s13287-020-01983-2. PubMed
A brainstem peptide system activated at birth protects postnatal breathing. Shi Y, Stornetta DS, Reklow RJ, Sahu A, Wabara Y, Nguyen A, Li K, Zhang Y, Perez-Reyes E, Ross RA, Lowell BB, Stornetta RL, Funk GD, Guyenet PG, Bayliss DA. Nature. 2021 Jan;589(7842):426-430. doi: 10.1038/s41586-020-2991-4. Epub 2020 Dec 2. PubMed
Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells. Awan T, Babendreyer A, Mahmood Alvi A, Dusterhoft S, Lambertz D, Bartsch JW, Liedtke C, Ludwig A. J Cell Mol Med. 2021 Feb;25(4):1982-1999. doi: 10.1111/jcmm.16015. Epub 2020 Dec 13. PubMed
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation. Dorronsoro A, Lang V, Ferrin I, Fernandez-Rueda J, Zabaleta L, Perez-Ruiz E, Sepulveda P, Trigueros C. Sci Rep. 2020 Dec 14;10(1):21853. doi: 10.1038/s41598-020-78864-4. PubMed
An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility. Iwata S, Morikawa M, Takei Y, Hirokawa N. Sci Adv. 2020 Dec 16;6(51). pii: 6/51/eabc8355. doi: 10.1126/sciadv.abc8355. Print 2020 Dec. PubMed
TMEM70 forms oligomeric scaffolds within mitochondrial cristae promoting in situ assembly of mammalian ATP synthase proton channel. Bahri H, Buratto J, Rojo M, Dompierre JP, Salin B, Blancard C, Cuvellier S, Rose M, Ben Ammar Elgaaied A, Tetaud E, di Rago JP, Devin A, Duvezin-Caubet S. Biochim Biophys Acta Mol Cell Res. 2021 Apr;1868(4):118942. doi: 10.1016/j.bbamcr.2020.118942. Epub 2020 Dec 23. PubMed
Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro. Awan T, Babendreyer A, Wozniak J, Alvi AM, Sterzer V, Cook L, Bartsch JW, Liedtke C, Yildiz D, Ludwig A. Mediators Inflamm. 2021 Mar 11;2021:6665028. doi: 10.1155/2021/6665028. eCollection 2021. PubMed
hTERT Downregulation Attenuates Resistance to DOX, Impairs FAK-Mediated Adhesion, and Leads to Autophagy Induction in Breast Cancer Cells. Romaniuk-Drapala A, Toton E, Konieczna N, Machnik M, Barczak W, Kowal D, Kopczynski P, Kaczmarek M, Rubis B. Cells. 2021 Apr 10;10(4). pii: cells10040867. doi: 10.3390/cells10040867. PubMed
Widespread displacement of DNA- and RNA-binding factors underlies toxicity of arginine-rich cell-penetrating peptides. Lafarga V, Sirozh O, Diaz-Lopez I, Galarreta A, Hisaoka M, Zarzuela E, Boskovic J, Jovanovic B, Fernandez-Leiro R, Munoz J, Stoecklin G, Ventoso I, Fernandez-Capetillo O. EMBO J. 2021 Jul 1;40(13):e103311. doi: 10.15252/embj.2019103311. Epub 2021 May 12. PubMed
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care. Gutmann C, Takov K, Burnap SA, Singh B, Ali H, Theofilatos K, Reed E, Hasman M, Nabeebaccus A, Fish M, McPhail MJ, O'Gallagher K, Schmidt LE, Cassel C, Rienks M, Yin X, Auzinger G, Napoli S, Mujib SF, Trovato F, Sanderson B, Merrick B, Niazi U, Saqi M, Dimitrakopoulou K, Fernandez-Leiro R, Braun S, Kronstein-Wiedemann R, Doores KJ, Edgeworth JD, Shah AM, Bornstein SR, Tonn T, Hayday AC, Giacca M, Shankar-Hari M, Mayr M. Nat Commun. 2021 Jun 7;12(1):3406. doi: 10.1038/s41467-021-23494-1. PubMed
The Role of Smad2 in Adult Neuroplasticity as Seen through Hippocampal-Dependent Spatial Learning/Memory and Neurogenesis. Gradari S, Herrera A, Tezanos P, Fontan-Lozano A, Pons S, Trejo JL. J Neurosci. 2021 Aug 11;41(32):6836-6849. doi: 10.1523/JNEUROSCI.2619-20.2021. Epub 2021 Jul 1. PubMed
Dlx5 promotes cancer progression through regulation of CCND1 in oral squamous cell carcinoma (OSCC). Zhang J, Wu J, Chen Y, Zhang W. Biochem Cell Biol. 2021 Aug;99(4):424-434. doi: 10.1139/bcb-2020-0523. Epub 2021 Jul 20. PubMed
Inhibition of the H3K27 demethylase UTX enhances the epigenetic silencing of HIV proviruses and induces HIV-1 DNA hypermethylation but fails to permanently block HIV reactivation. Nguyen K, Dobrowolski C, Shukla M, Cho WK, Luttge B, Karn J. PLoS Pathog. 2021 Oct 21;17(10):e1010014. doi: 10.1371/journal.ppat.1010014. eCollection 2021 Oct. PubMed
JAM-A interacts with alpha3beta1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells. Tholmann S, Seebach J, Otani T, Florin L, Schnittler H, Gerke V, Furuse M, Ebnet K. Cell Mol Life Sci. 2022 Jan 24;79(2):88. doi: 10.1007/s00018-022-04140-5. PubMed
Pseudomonas aeruginosa Triggered Exosomal Release of ADAM10 Mediates Proteolytic Cleavage in Trans. Aljohmani A, Opitz B, Bischoff M, Yildiz D. Int J Mol Sci. 2022 Jan 23;23(3). pii: ijms23031259. doi: 10.3390/ijms23031259. PubMed
A balanced Oct4 interactome is crucial for maintaining pluripotency. Han D, Wu G, Chen R, Drexler HCA, MacCarthy CM, Kim KP, Adachi K, Gerovska D, Mavrommatis L, Bedzhov I, Arauzo-Bravo MJ, Scholer HR. Sci Adv. 2022 Feb 18;8(7):eabe4375. doi: 10.1126/sciadv.abe4375. Epub 2022 Feb 16. PubMed
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