SARS-CoV-2 S HexaPro Citations (56)
Originally described in: Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.Hsieh CL, Goldsmith JA, Schaub JM, DiVenere AM, Kuo HC, Javanmardi K, Le KC, Wrapp D, Lee AG, Liu Y, Chou CW, Byrne PO, Hjorth CK, Johnson NV, Ludes-Meyers J, Nguyen AW, Park J, Wang N, Amengor D, Lavinder JJ, Ippolito GC, Maynard JA, Finkelstein IJ, McLellan JS Science. 2020 Sep 18;369(6510):1501-1505. doi: 10.1126/science.abd0826. Epub 2020 Jul 23. PubMed Journal
Articles Citing SARS-CoV-2 S HexaPro
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Synthetic nanobody-SARS-CoV-2 receptor-binding domain structures identify distinct epitopes.
Ahmad J, Jiang J, Boyd LF, Natarajan K, Margulies DH.
bioRxiv. 2021 Jan 27. doi: 10.1101/2021.01.27.428466.
PubMed
Associated Plasmids |
| A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Liu H, Yuan M, Huang D, Bangaru S, Zhao F, Lee CD, Peng L, Barman S, Zhu X, Nemazee D, Burton DR, van Gils MJ, Sanders RW, Kornau HC, Reincke SM, Pruss H, Kreye J, Wu NC, Ward AB, Wilson IA. Cell Host Microbe. 2021 May 12;29(5):806-818.e6. doi: 10.1016/j.chom.2021.04.005. Epub 2021 Apr 15. PubMed |
| Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies. Zhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S. PLoS Biol. 2021 Apr 29;19(4):e3001237. doi: 10.1371/journal.pbio.3001237. eCollection 2021 Apr. PubMed |
| Mice Immunized with the Vaccine Candidate HexaPro Spike Produce Neutralizing Antibodies against SARS-CoV-2. Seephetdee C, Buasri N, Bhukhai K, Srisanga K, Manopwisedjaroen S, Lertjintanakit S, Phueakphud N, Pakiranay C, Kangwanrangsan N, Srichatrapimuk S, Kirdlarp S, Sungkanuparph S, Chutipongtanate S, Thitithanyanont A, Hongeng S, Wongtrakoongate P. Vaccines (Basel). 2021 May 12;9(5). pii: vaccines9050498. doi: 10.3390/vaccines9050498. PubMed |
| Structures of synthetic nanobody-SARS-CoV-2-RBD complexes reveal distinct sites of interaction and recognition of variants. Margulies D, Ahmad J, Jiang J, Boyd L, Zeher A, Huang R, Xia D, Natarajan K. Res Sq. 2021 Jun 16. doi: 10.21203/rs.3.rs-625642/v1. PubMed |
| Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. Guttler T, Aksu M, Dickmanns A, Stegmann KM, Gregor K, Rees R, Taxer W, Rymarenko O, Schunemann J, Dienemann C, Gunkel P, Mussil B, Krull J, Teichmann U, Gross U, Cordes VC, Dobbelstein M, Gorlich D. EMBO J. 2021 Oct 1;40(19):e107985. doi: 10.15252/embj.2021107985. Epub 2021 Aug 9. PubMed |
| A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants. Schmitz AJ, Turner JS, Liu Z, Zhou JQ, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Altomare CG, Alsoussi WB, Case JB, VanBlargan LA, Lei T, Thapa M, Amanat F, Jeevan T, Fabrizio T, O'Halloran JA, Shi PY, Presti RM, Webby RJ, Krammer F, Whelan SPJ, Bajic G, Diamond MS, Boon ACM, Ellebedy AH. Immunity. 2021 Sep 14;54(9):2159-2166.e6. doi: 10.1016/j.immuni.2021.08.013. Epub 2021 Aug 17. PubMed |
| Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. Ahmad J, Jiang J, Boyd LF, Zeher A, Huang R, Xia D, Natarajan K, Margulies DH. J Biol Chem. 2021 Oct;297(4):101202. doi: 10.1016/j.jbc.2021.101202. Epub 2021 Sep 16. PubMed |
| Expression and characterization of SARS-CoV-2 spike proteins. Schaub JM, Chou CW, Kuo HC, Javanmardi K, Hsieh CL, Goldsmith J, DiVenere AM, Le KC, Wrapp D, Byrne PO, Hjorth CK, Johnson NV, Ludes-Meyers J, Nguyen AW, Wang N, Lavinder JJ, Ippolito GC, Maynard JA, McLellan JS, Finkelstein IJ. Nat Protoc. 2021 Nov;16(11):5339-5356. doi: 10.1038/s41596-021-00623-0. Epub 2021 Oct 5. PubMed |
| SARS-CoV-2 spike-specific memory B cells express markers of durable immunity after non-severe COVID-19 but not after severe disease. Reyes RA, Clarke K, Gonzales SJ, Cantwell AM, Garza R, Catano G, Tragus RE, Patterson TF, Bol S, Bunnik EM. bioRxiv. 2021 Sep 27. doi: 10.1101/2021.09.24.461732. PubMed |
| Complete protection by a single-dose skin patch-delivered SARS-CoV-2 spike vaccine. McMillan CLD, Choo JJY, Idris A, Supramaniam A, Modhiran N, Amarilla AA, Isaacs A, Cheung STM, Liang B, Bielefeldt-Ohmann H, Azuar A, Acharya D, Kelly G, Fernando GJP, Landsberg MJ, Khromykh AA, Watterson D, Young PR, McMillan NAJ, Muller DA. Sci Adv. 2021 Oct 29;7(44):eabj8065. doi: 10.1126/sciadv.abj8065. Epub 2021 Oct 29. PubMed |
Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models.
Sheward DJ, Mandolesi M, Urgard E, Kim C, Hanke L, Perez Vidakovics L, Pankow A, Smith NL, Castro Dopico X, McInerney GM, Coquet JM, Karlsson Hedestam GB, Murrell B.
Cell Rep Med. 2021 Nov 16;2(11):100450. doi: 10.1016/j.xcrm.2021.100450. Epub 2021 Oct 23.
PubMed
Associated Plasmids |
| Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding. Mannar D, Saville JW, Zhu X, Srivastava SS, Berezuk AM, Zhou S, Tuttle KS, Kim A, Li W, Dimitrov DS, Subramaniam S. Cell Rep. 2021 Dec 21;37(12):110156. doi: 10.1016/j.celrep.2021.110156. Epub 2021 Dec 4. PubMed |
Rapid characterization of spike variants via mammalian cell surface display.
Javanmardi K, Chou CW, Terrace CI, Annapareddy A, Kaoud TS, Guo Q, Lutgens J, Zorkic H, Horton AP, Gardner EC, Nguyen G, Boutz DR, Goike J, Voss WN, Kuo HC, Dalby KN, Gollihar JD, Finkelstein IJ.
Mol Cell. 2021 Dec 16;81(24):5099-5111.e8. doi: 10.1016/j.molcel.2021.11.024.
PubMed
Associated Plasmids |
SARS-CoV-2 spike-specific memory B cells express higher levels of T-bet and FcRL5 after non-severe COVID-19 as compared to severe disease.
Reyes RA, Clarke K, Gonzales SJ, Cantwell AM, Garza R, Catano G, Tragus RE, Patterson TF, Bol S, Bunnik EM.
PLoS One. 2021 Dec 22;16(12):e0261656. doi: 10.1371/journal.pone.0261656. eCollection 2021.
PubMed
Associated Plasmids |
| Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants. Saville JW, Mannar D, Zhu X, Srivastava SS, Berezuk AM, Demers JP, Zhou S, Tuttle KS, Sekirov I, Kim A, Li W, Dimitrov DS, Subramaniam S. Nat Commun. 2022 Feb 8;13(1):742. doi: 10.1038/s41467-022-28324-6. PubMed |
| Cryo-EM structure of the SARS-CoV-2 Omicron spike. Cerutti G, Guo Y, Liu L, Liu L, Zhang Z, Luo Y, Huang Y, Wang HH, Ho DD, Sheng Z, Shapiro L. Cell Rep. 2022 Mar 1;38(9):110428. doi: 10.1016/j.celrep.2022.110428. Epub 2022 Feb 7. PubMed |
| Antibody Response to SARS-CoV-2 Infection and Vaccination in COVID-19-naive and Experienced Individuals. Uprichard SL, O'Brien A, Evdokimova M, Rowe CL, Joyce C, Hackbart M, Cruz-Pulido YE, Cohen CA, Rock ML, Dye JM, Kuehnert P, Ricks KM, Casper M, Linhart L, Anderson K, Kirk L, Maggiore JA, Herbert AS, Clark NM, Reid GE, Baker SC. Viruses. 2022 Feb 10;14(2). pii: v14020370. doi: 10.3390/v14020370. PubMed |
| Superimmunity by pan-sarbecovirus nanobodies. Xiang Y, Huang W, Liu H, Sang Z, Nambulli S, Tubiana J, Williams KL Jr, Duprex WP, Schneidman-Duhovny D, Wilson IA, Taylor DJ, Shi Y. Cell Rep. 2022 Jun 28;39(13):111004. doi: 10.1016/j.celrep.2022.111004. Epub 2022 Jun 8. PubMed |
| Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern. McMillan CLD, Amarilla AA, Modhiran N, Choo JJY, Azuar A, Honeyman KE, Khromykh AA, Young PR, Watterson D, Muller DA. Vaccine. 2022 Aug 12;40(34):4929-4932. doi: 10.1016/j.vaccine.2022.07.013. Epub 2022 Jul 18. PubMed |
| SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization. Mannar D, Saville JW, Sun Z, Zhu X, Marti MM, Srivastava SS, Berezuk AM, Zhou S, Tuttle KS, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Jacobs JL, Barratt-Boyes SM, Mellors JW, Dimitrov DS, Li W, Subramaniam S. Nat Commun. 2022 Aug 18;13(1):4696. doi: 10.1038/s41467-022-32262-8. PubMed |
| Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein. Javanmardi K, Segall-Shapiro TH, Chou CW, Boutz DR, Olsen RJ, Xie X, Xia H, Shi PY, Johnson CD, Annapareddy A, Weaver S, Musser JM, Ellington AD, Finkelstein IJ, Gollihar JD. Cell Host Microbe. 2022 Sep 14;30(9):1242-1254.e6. doi: 10.1016/j.chom.2022.07.016. Epub 2022 Aug 4. PubMed |
| Selective reversed-phase high-performance liquid chromatography method for the determination of intact SARS-CoV-2 spike protein. Lorbetskie B, White T, Creskey M, Zhang X, Girard M, Tam RY, Sauve S, Lu H. J Chromatogr A. 2022 Sep 13;1680:463424. doi: 10.1016/j.chroma.2022.463424. Epub 2022 Aug 16. PubMed |
| Utility of in silico-identified-peptides in spike-S1 domain and nucleocapsid of SARS-CoV-2 for antibody detection in COVID-19 patients and antibody production. Cortes-Sarabia K, Luna-Pineda VM, Rodriguez-Ruiz HA, Leyva-Vazquez MA, Hernandez-Sotelo D, Beltran-Anaya FO, Vences-Velazquez A, Del Moral-Hernandez O, Illades-Aguiar B. Sci Rep. 2022 Sep 5;12(1):15057. doi: 10.1038/s41598-022-18517-w. PubMed |
| SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly. Onnis A, Andreano E, Cassioli C, Finetti F, Della Bella C, Staufer O, Pantano E, Abbiento V, Marotta G, D'Elios MM, Rappuoli R, Baldari CT. J Exp Med. 2023 Feb 6;220(2):e20220906. doi: 10.1084/jem.20220906. Epub 2022 Nov 15. PubMed |
| Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice. Ashhurst AS, Johansen MD, Maxwell JWC, Stockdale S, Ashley CL, Aggarwal A, Siddiquee R, Miemczyk S, Nguyen DH, Mackay JP, Counoupas C, Byrne SN, Turville S, Steain M, Triccas JA, Hansbro PM, Payne RJ, Britton WJ. Nat Commun. 2022 Nov 15;13(1):6972. doi: 10.1038/s41467-022-34297-3. PubMed |
| Variations within the Glycan Shield of SARS-CoV-2 Impact Viral Spike Dynamics. Newby ML, Fogarty CA, Allen JD, Butler J, Fadda E, Crispin M. J Mol Biol. 2023 Feb 28;435(4):167928. doi: 10.1016/j.jmb.2022.167928. Epub 2022 Dec 21. PubMed |
| Targeting Spike Glycans to Inhibit SARS-CoV2 Viral Entry. Guseman AJ, Rennick LJ, Nambulli S, Roy CN, Martinez DR, Yang DT, Bhinderwhala F, Vergara S, Baric RS, Ambrose Z, Duprex WP, Gronenborn AM. bioRxiv. 2022 Dec 22:2022.12.22.521642. doi: 10.1101/2022.12.22.521642. Preprint. PubMed |
| Monoclonal Antibodies Specific for SARS-CoV-2 Spike Protein Suitable for Multiple Applications for Current Variants of Concern. Morgan MS, Yan K, Le TT, Johnston RA, Amarilla AA, Muller DA, McMillan CLD, Modhiran N, Watterson D, Potter JR, Sng JDJ, Lor M, Paramitha D, Isaacs A, Khromykh AA, Hall RA, Suhrbier A, Rawle DJ, Hobson-Peters J. Viruses. 2022 Dec 31;15(1):139. doi: 10.3390/v15010139. PubMed |
| SARS-CoV-2 Spike Protein Downregulates Cell Surface alpha7nAChR through a Helical Motif in the Spike Neck. Tillman TS, Chen Q, Bondarenko V, Coleman JA, Xu Y, Tang P. ACS Chem Neurosci. 2023 Feb 15;14(4):689-698. doi: 10.1021/acschemneuro.2c00610. Epub 2023 Feb 6. PubMed |
| Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs. Loo L, Waller MA, Moreno CL, Cole AJ, Stella AO, Pop OT, Jochum AK, Ali OH, Denes CE, Hamoudi Z, Chung F, Aggarwal A, Low JKK, Patel K, Siddiquee R, Kang T, Mathivanan S, Mackay JP, Jochum W, Flatz L, Hesselson D, Turville S, Neely GG. PLoS Biol. 2023 Feb 9;21(2):e3001967. doi: 10.1371/journal.pbio.3001967. eCollection 2023 Feb. PubMed |
| Uncovering the Role of N-Glycan Occupancy on the Cooperative Assembly of Spike and Angiotensin Converting Enzyme 2 Complexes: Insights from Glycoengineering and Native Mass Spectrometry. El-Baba TJ, Lutomski CA, Burnap SA, Bolla JR, Baker LA, Baldwin AJ, Struwe WB, Robinson CV. J Am Chem Soc. 2023 Apr 12;145(14):8021-8032. doi: 10.1021/jacs.3c00291. Epub 2023 Mar 31. PubMed |
| Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection. Vu MN, Alvarado RE, Morris DR, Lokugamage KG, Zhou Y, Morgan AL, Estes LK, McLeland AM, Schindewolf C, Plante JA, Ahearn YP, Meyers WM, Murray JT, Weaver S, Walker DH, Russell WK, Routh AL, Plante KS, Menachery VD. bioRxiv. 2023 Jul 10:2023.04.17.536926. doi: 10.1101/2023.04.17.536926. Preprint. PubMed |
| Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response. Patel A, Kumar S, Lai L, Chakravarthy C, Valanparambil R, Reddy ES, Gottimukkala K, Bajpai P, Raju DR, Edara VV, Davis-Gardner ME, Linderman S, Dixit K, Sharma P, Mantus G, Cheedarla N, Verkerke HP, Frank F, Neish AS, Roback JD, Davis CW, Wrammert J, Ahmed R, Suthar MS, Sharma A, Murali-Krishna K, Chandele A, Ortlund EA. Structure. 2023 Jul 6;31(7):801-811.e5. doi: 10.1016/j.str.2023.04.010. Epub 2023 May 11. PubMed |
| Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection. Guenthoer J, Lilly M, Starr TN, Dadonaite B, Lovendahl KN, Croft JT, Stoddard CI, Chohan V, Ding S, Ruiz F, Kopp MS, Finzi A, Bloom JD, Chu HY, Lee KK, Overbaugh J. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2220948120. doi: 10.1073/pnas.2220948120. Epub 2023 May 30. PubMed |
| SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity. Martinez-Marmol R, Giordano-Santini R, Kaulich E, Cho AN, Przybyla M, Riyadh MA, Robinson E, Chew KY, Amor R, Meunier FA, Balistreri G, Short KR, Ke YD, Ittner LM, Hilliard MA. Sci Adv. 2023 Jun 9;9(23):eadg2248. doi: 10.1126/sciadv.adg2248. Epub 2023 Jun 7. PubMed |
| Widespread impact of immunoglobulin V gene allelic polymorphisms on antibody reactivity. Yuan M, Feng Z, Lv H, So N, Shen IR, Tan TJC, Teo QW, Ouyang WO, Talmage L, Wilson IA, Wu NC. bioRxiv. 2023 Jun 7:2023.06.06.543969. doi: 10.1101/2023.06.06.543969. Preprint. PubMed |
| Comparison of DNA vaccines with AS03 as an adjuvant and an mRNA vaccine against SARS-CoV-2. Neeli P, Chai D, Wang X, Sobhani N, Udeani G, Li Y. iScience. 2023 Jun 16;26(7):107120. doi: 10.1016/j.isci.2023.107120. eCollection 2023 Jul 21. PubMed |
| Adaptation of the binding domain of Lactobacillus acidophilus S-layer protein as a molecular tag for affinity chromatography development. Muruaga EJ, Uriza PJ, Eckert GAK, Pepe MV, Duarte CM, Roset MS, Briones G. Front Microbiol. 2023 Jun 13;14:1210898. doi: 10.3389/fmicb.2023.1210898. eCollection 2023. PubMed |
| Targeting spike glycans to inhibit SARS-CoV2 viral entry. Guseman AJ, Rennick LJ, Nambulli S, Roy CN, Martinez DR, Yang DT, Bhinderwala F, Vergara S, Schaefer A, Baric RS, Ambrose Z, Duprex WP, Gronenborn AM. Proc Natl Acad Sci U S A. 2023 Sep 19;120(38):e2301518120. doi: 10.1073/pnas.2301518120. Epub 2023 Sep 11. PubMed |
| Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking. Liu L, Casner RG, Guo Y, Wang Q, Iketani S, Chan JF, Yu J, Dadonaite B, Nair MS, Mohri H, Reddem ER, Yuan S, Poon VK, Chan CC, Yuen KY, Sheng Z, Huang Y, Bloom JD, Shapiro L, Ho DD. Immunity. 2023 Oct 10;56(10):2442-2455.e8. doi: 10.1016/j.immuni.2023.09.003. Epub 2023 Sep 29. PubMed |
| Widespread impact of immunoglobulin V-gene allelic polymorphisms on antibody reactivity. Yuan M, Feng Z, Lv H, So N, Shen IR, Tan TJC, Teo QW, Ouyang WO, Talmage L, Wilson IA, Wu NC. Cell Rep. 2023 Oct 31;42(10):113194. doi: 10.1016/j.celrep.2023.113194. Epub 2023 Sep 30. PubMed |
| Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models. Guimaraes LC, Costa PAC, Scalzo Junior SRA, Ferreira HAS, Braga ACS, de Oliveira LC, Figueiredo MM, Shepherd S, Hamilton A, Queiroz-Junior CM, da Silva WN, da Silva NJA, Rodrigues Alves MT, Santos AK, de Faria KKS, Marim FM, Fukumasu H, Birbrair A, Teixeira-Carvalho A, de Aguiar RS, Mitchell MJ, Teixeira MM, Vasconcelos Costa V, Frezard F, Guimaraes PPG. Nat Commun. 2024 Jan 18;15(1):590. doi: 10.1038/s41467-024-44830-1. PubMed |
| Precise control of digital dental unit to reduce aerosol and splatter production: new challenges for future epidemics. Yu Y, Wu X, Sun Y. BMC Oral Health. 2024 Feb 10;24(1):213. doi: 10.1186/s12903-024-03980-w. PubMed |
| Murine alveolar macrophages rapidly accumulate intranasally administered SARS-CoV-2 Spike protein leading to neutrophil recruitment and damage. Park C, Hwang IY, Yan SL, Vimonpatranon S, Wei D, Van Ryk D, Girard A, Cicala C, Arthos J, Kehrl JH. Elife. 2024 Mar 20;12:RP86764. doi: 10.7554/eLife.86764. PubMed |
Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses.
Hills RA, Tan TK, Cohen AA, Keeffe JR, Keeble AH, Gnanapragasam PNP, Storm KN, Rorick AV, West AP Jr, Hill ML, Liu S, Gilbert-Jaramillo J, Afzal M, Napier A, Admans G, James WS, Bjorkman PJ, Townsend AR, Howarth MR.
Nat Nanotechnol. 2024 May 6. doi: 10.1038/s41565-024-01655-9.
PubMed
Associated Plasmids |
| Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination. Voss WN, Mallory MA, Byrne PO, Marchioni JM, Knudson SA, Powers JM, Leist SR, Dadonaite B, Townsend DR, Kain J, Huang Y, Satterwhite E, Castillo IN, Mattocks M, Paresi C, Munt JE, Scobey T, Seeger A, Premkumar L, Bloom JD, Georgiou G, McLellan JS, Baric RS, Lavinder JJ, Ippolito GC. Cell Rep Med. 2024 Aug 20;5(8):101668. doi: 10.1016/j.xcrm.2024.101668. Epub 2024 Aug 1. PubMed |
| The host protease KLK5 primes and activates spike proteins to promote human betacoronavirus replication and lung inflammation. Kim H, Kang Y, Kim S, Park D, Heo SY, Yoo JS, Choi I, N MPA, Ahn JW, Yang JS, Bak N, Kim KK, Lee JY, Choi YK. Sci Signal. 2024 Aug 20;17(850):eadn3785. doi: 10.1126/scisignal.adn3785. Epub 2024 Aug 20. PubMed |
| Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients. Sakakibara S, Liu YC, Ishikawa M, Edahiro R, Shirai Y, Haruna S, El Hussien MA, Xu Z, Li S, Yamaguchi Y, Murakami T, Morita T, Kato Y, Hirata H, Takeda Y, Sugihara F, Naito Y, Motooka D, Tsai CY, Ono C, Matsuura Y, Wing JB, Matsumoto H, Ogura H, Okada M, Kumanogoh A, Okada Y, Standley DM, Kikutani H, Okuzaki D. Life Sci Alliance. 2024 Sep 17;7(12):e202402774. doi: 10.26508/lsa.202402774. Print 2024 Dec. PubMed |
| A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation. Stein SC, Hansen G, Ssebyatika G, Stroh LJ, Ochulor O, Herold E, Schwarzloh B, Mutschall D, Zischke J, Cordes AK, Schneider T, Hinrichs I, Blasczyk R, Kleine-Weber H, Hoffmann M, Klein F, Kaiser FK, Gonzalez-Hernandez M, Armando F, Ciurkiewicz M, Beythien G, Pohlmann S, Baumgartner W, Osterhaus A, Schulz TF, Krey T. J Virol. 2024 Dec 17;98(12):e0122324. doi: 10.1128/jvi.01223-24. Epub 2024 Nov 4. PubMed |
| Skin patch delivery of a SARS-CoV-2 spike DNA vaccine produces broad neutralising antibody responses. McMillan CLD, Corner AV, Wijesundara DK, Choo JJY, Pittayakhajonwut D, Poredi I, Parry RH, Bindra GK, Bruce KL, Khromykh AA, Fernando GJP, Dapremont L, Young PR, Muller DA. Heliyon. 2025 Feb 7;11(4):e42533. doi: 10.1016/j.heliyon.2025.e42533. eCollection 2025 Feb 28. PubMed |
| Cryo-EM reveals conformational variability in the SARS-CoV-2 spike protein RBD induced by two broadly neutralizing monoclonal antibodies. Rencilin CF, Chatterjee A, Ansari MY, Deshpande S, Mukherjee S, Singh R, Jayatheertha SB, Reddy PM, Hingankar N, Varadarajan R, Bhattacharya J, Dutta S. RSC Adv. 2025 May 6;15(18):14385-14399. doi: 10.1039/d5ra00373c. eCollection 2025 Apr 28. PubMed |
| An RGD motif on SARS-CoV-2 Spike induces TGF-beta signaling and downregulates interferon. Gracie NP, Aggarwal A, Luo R, Spicer M, Idrees S, Ashley CL, Alca S, Ison T, Steain MC, Patel K, Siddiquee R, Low JKK, Mackay JP, Denes CE, Neely GG, Faiz A, Turville SG, Newsome TP. J Virol. 2025 Sep 23;99(9):e0043525. doi: 10.1128/jvi.00435-25. Epub 2025 Sep 4. PubMed |
| Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist. Gonzales J, Young T, Choi H, Park M, Jewel Y, Fan C, Purohit R, Bjorkman PJ, Williams JC. Commun Biol. 2025 Oct 6;8(1):1428. doi: 10.1038/s42003-025-08819-w. PubMed |
| P selectin promotes SARS-CoV-2 interactions with platelets and the endothelium. Moreno CL, Castanheira FV, Ospina Stella A, Chung F, Aggarwal A, Cole AJ, Loo L, Dupuy A, Kong YX, Hagimola L, Fenwick J, Coleman PR, Carr R, Du TY, Ison T, Newton M, Bui-Marinos MP, Cohen SB, Corcoran JA, Hesselson D, Gamble JR, Passam FH, Turville SG, Kubes P, Neely GG. J Clin Invest. 2025 Nov 17;135(22):e184514. doi: 10.1172/JCI184514. eCollection 2025 Nov 17. PubMed |
| Cross-reactivity IgG, viral load, severity and vaccination outcome as an approach for understanding humoral immune response against SARS-CoV-2. Contreras-Villa J, Rodriguez-Martinez G, Parra-Ortega I, Romo-Castillo M, Cortes-Sarabia K, Saldana-Ahuactzi Z, Flores-Alanis A, Aureoles-Romero A, Salazar-Garcia M, Gonzalez J, Eslava-Campos CA, Hernandez-Chinas U, Cruz-Rangel A, Morales-Espinosa R, Cancino-Diaz ME, Luna-Pineda VM. BMC Infect Dis. 2025 Nov 18;25(1):1606. doi: 10.1186/s12879-025-12038-3. PubMed |
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