pBABE-hygro-hTERT Citations (43)
Originally described in: Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA Proc Natl Acad Sci U S A 1998 Dec 8;95(25):14723-8. PubMed Journal
Articles Citing pBABE-hygro-hTERT
| Articles |
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Reprogramming of human somatic cells to pluripotency with defined factors.
Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA, Lerou PH, Lensch MW, Daley GQ.
Nature. 2008 Jan 10. 451(7175):141-6.
PubMed
Associated Plasmids |
| Generation of human-induced pluripotent stem cells. Park IH, Lerou PH, Zhao R, Huo H, Daley GQ. Nat Protoc. 2008 . 3(7):1180-6. PubMed |
| 2D difference gel electrophoresis analysis of different time points during the course of neoplastic transformation of human mammary epithelial cells. DeAngelis JT, Li Y, Mitchell N, Wilson L, Kim H, Tollefsbol TO. J Proteome Res. 2011 Feb 4;10(2):447-58. doi: 10.1021/pr100533k. Epub 2010 Dec 20. PubMed |
| Differentiation and neuro-protective properties of immortalized human tooth germ stem cells. Yalvac ME, Yilmaz A, Mercan D, Aydin S, Dogan A, Arslan A, Demir Z, Salafutdinov II, Shafigullina AK, Sahin F, Rizvanov AA, Palotas A. Neurochem Res. 2011 Dec;36(12):2227-35. doi: 10.1007/s11064-011-0546-7. Epub 2011 Jul 22. PubMed |
| QKI-mediated alternative splicing of the histone variant MacroH2A1 regulates cancer cell proliferation. Novikov L, Park JW, Chen H, Klerman H, Jalloh AS, Gamble MJ. Mol Cell Biol. 2011 Oct;31(20):4244-55. doi: 10.1128/MCB.05244-11. Epub 2011 Aug 15. PubMed |
| Modeling sarcomagenesis using multipotent mesenchymal stem cells. Rodriguez R, Rubio R, Menendez P. Cell Res. 2012 Jan;22(1):62-77. doi: 10.1038/cr.2011.157. Epub 2011 Sep 20. PubMed |
| Heterotypic three-dimensional in vitro modeling of stromal-epithelial interactions during ovarian cancer initiation and progression. Lawrenson K, Grun B, Gayther SA. J Vis Exp. 2012 Aug 28;(66):e4206. doi: 10.3791/4206. PubMed |
| A tumor suppressor role for srGAP3 in mammary epithelial cells. Lahoz A, Hall A. Oncogene. 2013 Oct;32(40):4854-60. doi: 10.1038/onc.2012.489. Epub 2012 Oct 29. PubMed |
| Magnetic separation and antibiotics selection enable enrichment of cells with ZFN/TALEN-induced mutations. Kim H, Kim MS, Wee G, Lee CI, Kim H, Kim JS. PLoS One. 2013;8(2):e56476. doi: 10.1371/journal.pone.0056476. Epub 2013 Feb 18. PubMed |
| hTERT extends the life of human fibroblasts without compromising type I interferon signaling. Smith MC, Goddard ET, Perusina Lanfranca M, Davido DJ. PLoS One. 2013;8(3):e58233. doi: 10.1371/journal.pone.0058233. Epub 2013 Mar 5. PubMed |
| Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis. Wiel C, Augert A, Vincent DF, Gitenay D, Vindrieux D, Le Calve B, Arfi V, Lallet-Daher H, Reynaud C, Treilleux I, Bartholin L, Lelievre E, Bernard D. Cell Death Dis. 2013 Oct 10;4:e855. doi: 10.1038/cddis.2013.382. PubMed |
| Telomerase protects werner syndrome lineage-specific stem cells from premature aging. Cheung HH, Liu X, Canterel-Thouennon L, Li L, Edmonson C, Rennert OM. Stem Cell Reports. 2014 Mar 27;2(4):534-46. doi: 10.1016/j.stemcr.2014.02.006. eCollection 2014 Apr 8. PubMed |
| Src as a novel therapeutic target for endometriosis. Lawrenson K, Lee N, Torres HA, Lee JM, Brueggmann D, Rao PN, Noushmehr H, Gayther SA. Gynecol Oncol. 2014 Oct;135(1):100-7. doi: 10.1016/j.ygyno.2014.06.016. Epub 2014 Jun 24. PubMed |
| A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds. Salvati E, Rizzo A, Iachettini S, Zizza P, Cingolani C, D'Angelo C, Porru M, Mondello C, Aiello A, Farsetti A, Gilson E, Leonetti C, Biroccio A. Nucleic Acids Res. 2015 Feb 18;43(3):1759-69. doi: 10.1093/nar/gkv006. Epub 2015 Jan 23. PubMed |
| Loss of LKB1 and p53 synergizes to alter fallopian tube epithelial phenotype and high-grade serous tumorigenesis. George SH, Milea A, Sowamber R, Chehade R, Tone A, Shaw PA. Oncogene. 2015 Mar 23. doi: 10.1038/onc.2015.62. PubMed |
| Humanization of the mouse mammary gland. Wronski A, Arendt LM, Kuperwasser C. Methods Mol Biol. 2015;1293:173-86. doi: 10.1007/978-1-4939-2519-3_10. PubMed |
| Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes. Xue R, Lynes MD, Dreyfuss JM, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, Cypess AM, Tseng YH. Nat Med. 2015 Jul;21(7):760-8. doi: 10.1038/nm.3881. Epub 2015 Jun 15. PubMed |
| Generation of human induced pluripotent stem cells using non-synthetic mRNA. Rohani L, Fabian C, Holland H, Naaldijk Y, Dressel R, Loffler-Wirth H, Binder H, Arnold A, Stolzing A. Stem Cell Res. 2016 May;16(3):662-72. doi: 10.1016/j.scr.2016.03.008. Epub 2016 Mar 23. PubMed |
| A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma. Cantarino N, Fernandez-Figueras MT, Valero V, Musulen E, Malinverni R, Granada I, Goldie SJ, Martin-Caballero J, Douet J, Forcales SV, Buschbeck M. Int J Cancer. 2016 Sep 1;139(5):1106-16. doi: 10.1002/ijc.30139. Epub 2016 May 5. PubMed |
| Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15. Brandt A, Lohers K, Beier M, Leube B, de Torres C, Mora J, Arora P, Jat PS, Royer-Pokora B. PLoS One. 2016 May 23;11(5):e0155561. doi: 10.1371/journal.pone.0155561. eCollection 2016. PubMed |
| cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus Infection. Lio CW, McDonald B, Takahashi M, Dhanwani R, Sharma N, Huang J, Pham E, Benedict CA, Sharma S. J Virol. 2016 Aug 12;90(17):7789-97. doi: 10.1128/JVI.01040-16. Print 2016 Sep 1. PubMed |
Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells.
Hayer A, Shao L, Chung M, Joubert LM, Yang HW, Tsai FC, Bisaria A, Betzig E, Meyer T.
Nat Cell Biol. 2016 Dec;18(12):1311-1323. doi: 10.1038/ncb3438. Epub 2016 Nov 14.
PubMed
Associated Plasmids |
| Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation. Berrios C, Padi M, Keibler MA, Park DE, Molla V, Cheng J, Lee SM, Stephanopoulos G, Quackenbush J, DeCaprio JA. PLoS Pathog. 2016 Nov 23;12(11):e1006020. doi: 10.1371/journal.ppat.1006020. eCollection 2016 Nov. PubMed |
| Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing. Selt F, Hohloch J, Hielscher T, Sahm F, Capper D, Korshunov A, Usta D, Brabetz S, Ridinger J, Ecker J, Oehme I, Gronych J, Marquardt V, Pauck D, Bachli H, Stiles CD, von Deimling A, Remke M, Schuhmann MU, Pfister SM, Brummer T, Jones DT, Witt O, Milde T. Oncotarget. 2017 Feb 14;8(7):11460-11479. doi: 10.18632/oncotarget.14004. PubMed |
| Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes. Kriszt R, Arai S, Itoh H, Lee MH, Goralczyk AG, Ang XM, Cypess AM, White AP, Shamsi F, Xue R, Lee JY, Lee SC, Hou Y, Kitaguchi T, Sudhaharan T, Ishiwata S, Lane EB, Chang YT, Tseng YH, Suzuki M, Raghunath M. Sci Rep. 2017 May 3;7(1):1383. doi: 10.1038/s41598-017-00291-9. PubMed |
| Analysis of post-transcriptional regulation during cancer progression using a donor-derived isogenic model of tumorigenesis. Bisogno LS, Keene JD. Methods. 2017 May 19. pii: S1046-2023(16)30448-0. doi: 10.1016/j.ymeth.2017.05.012. PubMed |
| Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation. Liu H, Dowdle JA, Khurshid S, Sullivan NJ, Bertos N, Rambani K, Mair M, Daniel P, Wheeler E, Tang X, Toth K, Lause M, Harrigan ME, Eiring K, Sullivan C, Sullivan MJ, Chang SW, Srivastava S, Conway JS, Kladney R, McElroy J, Bae S, Lu Y, Tofigh A, Saleh SMI, Fernandez SA, Parvin JD, Coppola V, Macrae ER, Majumder S, Shapiro CL, Yee LD, Ramaswamy B, Hallett M, Ostrowski MC, Park M, Chamberlin HM, Leone G. Dev Cell. 2017 May 22;41(4):392-407.e6. doi: 10.1016/j.devcel.2017.04.024. PubMed |
| Hsa-miR-155-5p drives aneuploidy at early stages of cellular transformation. Pagotto S, Veronese A, Soranno A, Lanuti P, Di Marco M, Russo MV, Ramassone A, Marchisio M, Simeone P, Guanciali-Franchi PE, Palka G, Costantini RM, Croce CM, Visone R. Oncotarget. 2018 Feb 7;9(16):13036-13047. doi: 10.18632/oncotarget.24437. eCollection 2018 Feb 27. PubMed |
| Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis. Sustarsic EG, Ma T, Lynes MD, Larsen M, Karavaeva I, Havelund JF, Nielsen CH, Jedrychowski MP, Moreno-Torres M, Lundh M, Plucinska K, Jespersen NZ, Grevengoed TJ, Kramar B, Peics J, Hansen JB, Shamsi F, Forss I, Neess D, Keipert S, Wang J, Stohlmann K, Brandslund I, Christensen C, Jorgensen ME, Linneberg A, Pedersen O, Kiebish MA, Qvortrup K, Han X, Pedersen BK, Jastroch M, Mandrup S, Kjaer A, Gygi SP, Hansen T, Gillum MP, Grarup N, Emanuelli B, Nielsen S, Scheele C, Tseng YH, Faergeman NJ, Gerhart-Hines Z. Cell Metab. 2018 Jul 3;28(1):159-174.e11. doi: 10.1016/j.cmet.2018.05.003. Epub 2018 May 31. PubMed |
| Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf(V600E)-Induced Tumorigenesis. Tao Y, Kang B, Petkovich DA, Bhandari YR, In J, Stein-O'Brien G, Kong X, Xie W, Zachos N, Maegawa S, Vaidya H, Brown S, Chiu Yen RW, Shao X, Thakor J, Lu Z, Cai Y, Zhang Y, Mallona I, Peinado MA, Zahnow CA, Ahuja N, Fertig E, Issa JP, Baylin SB, Easwaran H. Cancer Cell. 2019 Feb 11;35(2):315-328.e6. doi: 10.1016/j.ccell.2019.01.005. PubMed |
| Assessment of different strategies for scalable production and proliferation of human myoblasts. Chua MJ, Yildirim ED, Tan JE, Chua YB, Low SC, Ding SLS, Li CW, Jiang Z, Teh BT, Yu K, Shyh-Chang N. Cell Prolif. 2019 May;52(3):e12602. doi: 10.1111/cpr.12602. Epub 2019 Mar 19. PubMed |
| MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses. Chatterjee A, Kosmacek EA, Shrishrimal S, McDonald JT, Oberley-Deegan RE. Redox Biol. 2020 Jul;34:101542. doi: 10.1016/j.redox.2020.101542. Epub 2020 Apr 21. PubMed |
| Homozygous nonsense variant in LRIF1 associated with facioscapulohumeral muscular dystrophy. Hamanaka K, Sikrova D, Mitsuhashi S, Masuda H, Sekiguchi Y, Sugiyama A, Shibuya K, Lemmers RJLF, Goossens R, Ogawa M, Nagao K, Obuse C, Noguchi S, Hayashi YK, Kuwabara S, Balog J, Nishino I, van der Maarel SM. Neurology. 2020 Jun 9;94(23):e2441-e2447. doi: 10.1212/WNL.0000000000009617. Epub 2020 May 28. PubMed |
An efficient vector-based CRISPR/Cas9 system in an Oreochromis mossambicus cell line using endogenous promoters.
Hamar J, Kultz D.
Sci Rep. 2021 Apr 12;11(1):7854. doi: 10.1038/s41598-021-87068-3.
PubMed
Associated Plasmids |
| The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder. Nuebel E, Morgan JT, Fogarty S, Winter JM, Lettlova S, Berg JA, Chen YC, Kidwell CU, Maschek JA, Clowers KJ, Argyriou C, Chen L, Wittig I, Cox JE, Roh-Johnson M, Braverman N, Bonkowsky J, Gygi SP, Rutter J. EMBO Rep. 2021 Oct 5;22(10):e51991. doi: 10.15252/embr.202051991. Epub 2021 Aug 5. PubMed |
| Novel immortalization approach defers senescence of cultured canine adipose-derived mesenchymal stromal cells. Stojiljkovic A, Gaschen V, Forterre F, Rytz U, Stoffel MH, Bluteau J. Geroscience. 2022 Jun;44(3):1301-1323. doi: 10.1007/s11357-021-00488-x. Epub 2021 Nov 22. PubMed |
| MnTE-2-PyP protects fibroblast mitochondria from hyperglycemia and radiation exposure. Chatterjee A, Sakallioglu IT, Murthy D, Kosmacek EA, Singh PK, McDonald JT, Powers R, Oberley-Deegan RE. Redox Biol. 2022 Jun;52:102301. doi: 10.1016/j.redox.2022.102301. Epub 2022 Mar 24. PubMed |
| LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug. Cutano V, Ferreira Mendes JM, Escudeiro-Lopes S, Machado S, Vinaixa Forner J, Gonzales-Morena JM, Prevorovsky M, Zemlianski V, Feng Y, Kralova Viziova P, Hartmanova A, Malcekova B, Jakoube P, Iyer S, Keckesova Z. Life Sci Alliance. 2022 Nov 14;6(1):e202201510. doi: 10.26508/lsa.202201510. Print 2023 Jan. PubMed |
| Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma. Pai G, Roohollahi K, Rockx D, de Jong Y, Stoepker C, Pennings C, Rooimans M, Vriend L, Piersma S, Jimenez CR, De Menezes RX, Van Beusechem VW, Brakenhoff RH, Te Riele H, Wolthuis RMF, Dorsman JC. Commun Biol. 2023 Jan 13;6(1):37. doi: 10.1038/s42003-022-04389-3. PubMed |
| Selective Targeting of Cancer-Related G-Quadruplex Structures by the Natural Compound Dicentrine. Platella C, Ghirga F, Musumeci D, Quaglio D, Zizza P, Iachettini S, D'Angelo C, Biroccio A, Botta B, Mori M, Montesarchio D. Int J Mol Sci. 2023 Feb 17;24(4):4070. doi: 10.3390/ijms24044070. PubMed |
| PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment. Maresca C, Dello Stritto A, D'Angelo C, Petti E, Rizzo A, Vertecchi E, Berardinelli F, Bonanni L, Sgura A, Antoccia A, Graziani G, Biroccio A, Salvati E. Commun Biol. 2023 Mar 2;6(1):234. doi: 10.1038/s42003-023-04596-6. PubMed |
| Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Ho TLF, Lee MY, Goh HC, Ng GYN, Lee JJH, Kannan S, Lim YT, Zhao T, Lim EKH, Phua CZJ, Lee YF, Lim RYX, Ng PJH, Yuan J, Chan DKH, Lieske B, Chong CS, Lee KC, Lum J, Cheong WK, Yeoh KG, Tan KK, Sobota RM, Verma CS, Lane DP, Tam WL, Venkitaraman AR. Nat Commun. 2023 Mar 28;14(1):1726. doi: 10.1038/s41467-023-37223-3. PubMed |
| PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors. Searcy MB, Larsen RK 4th, Stevens BT, Zhang Y, Jin H, Drummond CJ, Langdon CG, Gadek KE, Vuong K, Reed KB, Garcia MR, Xu B, Kimbrough DW, Adkins GE, Djekidel N, Porter SN, Schreiner PA, Pruett-Miller SM, Abraham BJ, Rehg JE, Hatley ME. Nat Commun. 2023 Nov 15;14(1):7291. doi: 10.1038/s41467-023-43044-1. PubMed |
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