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cytoplasmic EKAR (Cerulean-Venus) Citations (12)

Originally described in: A genetically encoded fluorescent sensor of ERK activity
Harvey CD, Ehrhardt AG, Cellurale C, Zhong H, Yasuda R, Davis RJ, Svoboda K. PNAS 2008 Dec 9;105(49):19264-9
PubMed Journal

Articles Citing cytoplasmic EKAR (Cerulean-Venus)

Articles
An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels. Everett KL, Cooper DM. PLoS One. 2013 Sep 23;8(9):e75942. doi: 10.1371/journal.pone.0075942. eCollection 2013. PubMed
Macromolecular Hydrogen Sulfide Donors Trigger Spatiotemporally Confined Changes in Cell Signaling. Ercole F, Mansfeld FM, Kavallaris M, Whittaker MR, Quinn JF, Halls ML, Davis TP. Biomacromolecules. 2016 Jan 11;17(1):371-83. doi: 10.1021/acs.biomac.5b01469. Epub 2015 Dec 23. PubMed
Plasma membrane localization of the mu-opioid receptor controls spatiotemporal signaling. Halls ML, Yeatman HR, Nowell CJ, Thompson GL, Gondin AB, Civciristov S, Bunnett NW, Lambert NA, Poole DP, Canals M. Sci Signal. 2016 Feb 9;9(414):ra16. doi: 10.1126/scisignal.aac9177. PubMed
Glucagon-like peptide-1 receptor internalisation controls spatiotemporal signalling mediated by biased agonists. Fletcher MM, Halls ML, Zhao P, Clydesdale L, Christopoulos A, Sexton PM, Wootten D. Biochem Pharmacol. 2018 Oct;156:406-419. doi: 10.1016/j.bcp.2018.09.003. Epub 2018 Sep 7. PubMed
Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation. Yang JM, Bhattacharya S, West-Foyle H, Hung CF, Wu TC, Iglesias PA, Huang CH. Nat Commun. 2018 Nov 7;9(1):4673. doi: 10.1038/s41467-018-07150-9. PubMed
ERK mediated survival signaling is dependent on the Gq-G-protein coupled receptor type and subcellular localization in adult cardiac myocytes. Dahl EF, Wu SC, Healy CL, Perry J, O'Connell TD. J Mol Cell Cardiol. 2019 Feb;127:67-73. doi: 10.1016/j.yjmcc.2018.11.020. Epub 2018 Dec 4. PubMed
Enhanced in vivo-imaging in medaka by optimized anaesthesia, fluorescent protein selection and removal of pigmentation. Lischik CQ, Adelmann L, Wittbrodt J. PLoS One. 2019 Mar 7;14(3):e0212956. doi: 10.1371/journal.pone.0212956. eCollection 2019. PubMed
Not So Dry After All: DRY Mutants of the AT1A Receptor and H1 Receptor Can Induce G-Protein-Dependent Signaling. Pietraszewska-Bogiel A, Joosen L, Chertkova AO, Goedhart J. ACS Omega. 2020 Feb 3;5(6):2648-2659. doi: 10.1021/acsomega.9b03146. eCollection 2020 Feb 18. PubMed

Associated Plasmids

Predicting response to platinum and non-platinum drugs through bioluminescence resonance energy transfer (BRET) based bio-molecular interactions in platinum resistant epithelial ovarian cancer. Bishnu A, Mehrotra M, Dhadve A, Dimri S, De A, Ray P. Transl Oncol. 2021 Nov;14(11):101193. doi: 10.1016/j.tranon.2021.101193. Epub 2021 Aug 5. PubMed
Deciphering cell signaling networks with massively multiplexed biosensor barcoding. Yang JM, Chi WY, Liang J, Takayanagi S, Iglesias PA, Huang CH. Cell. 2021 Dec 9;184(25):6193-6206.e14. doi: 10.1016/j.cell.2021.11.005. Epub 2021 Nov 26. PubMed

Associated Plasmids

On the inference of ERK signaling dynamics from protein biosensor measurements. Rahman SMT, Haugh JM. Mol Biol Cell. 2023 May 15;34(6):ar60. doi: 10.1091/mbc.E22-10-0476. Epub 2023 Mar 8. PubMed
Optomechanically Actuated Hydrogel Platform for Cell Stimulation with Spatial and Temporal Resolution. Ramey-Ward AN, Dong Y, Yang J, Ogasawara H, Bremer-Sai EC, Brazhkina O, Franck C, Davis M, Salaita K. ACS Biomater Sci Eng. 2023 Sep 11;9(9):5361-5375. doi: 10.1021/acsbiomaterials.3c00516. Epub 2023 Aug 21. PubMed

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