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AAV:ITR-U6-sgRNA(backbone)-pCBh-Cre-WPRE-hGHpA-ITR Citations (21)

Originally described in: CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling.
Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, Anderson DG, Hacohen N, Regev A, Feng G, Sharp PA, Zhang F Cell. 2014 Sep 24. pii: S0092-8674(14)01163-5. doi: 10.1016/j.cell.2014.09.014.
PubMed Journal

Articles Citing AAV:ITR-U6-sgRNA(backbone)-pCBh-Cre-WPRE-hGHpA-ITR

GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Yamasaki T, Hoyos-Ramirez E, Martenson JS, Morimoto-Tomita M, Tomita S. Neuron. 2017 Mar 8;93(5):1138-1152.e6. doi: 10.1016/j.neuron.2017.02.023. PubMed
Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma. Huang J, Chen M, Whitley MJ, Kuo HC, Xu ES, Walens A, Mowery YM, Van Mater D, Eward WC, Cardona DM, Luo L, Ma Y, Lopez OM, Nelson CE, Robinson-Hamm JN, Reddy A, Dave SS, Gersbach CA, Dodd RD, Kirsch DG. Nat Commun. 2017 Jul 10;8:15999. doi: 10.1038/ncomms15999. PubMed
Distinct roles of neuronal and microglial CB2 cannabinoid receptors in the mouse hippocampus. Li Y, Kim J. Neuroscience. 2017 Sep 6. pii: S0306-4522(17)30629-2. doi: 10.1016/j.neuroscience.2017.08.053. PubMed

Associated Plasmids

Human glioblastoma arises from subventricular zone cells with low-level driver mutations. Lee JH, Lee JE, Kahng JY, Kim SH, Park JS, Yoon SJ, Um JY, Kim WK, Lee JK, Park J, Kim EH, Lee JH, Lee JH, Chung WS, Ju YS, Park SH, Chang JH, Kang SG, Lee JH. Nature. 2018 Aug;560(7717):243-247. doi: 10.1038/s41586-018-0389-3. Epub 2018 Aug 1. PubMed
NUAK2 is a critical YAP target in liver cancer. Yuan WC, Pepe-Mooney B, Galli GG, Dill MT, Huang HT, Hao M, Wang Y, Liang H, Calogero RA, Camargo FD. Nat Commun. 2018 Nov 16;9(1):4834. doi: 10.1038/s41467-018-07394-5. PubMed
CRMP2 mediates GSK3beta actions in the striatum on regulating neuronal structure and mania-like behavior. Kim W, Won SY, Yoon BJ. J Affect Disord. 2019 Feb 15;245:1079-1088. doi: 10.1016/j.jad.2018.10.371. Epub 2018 Nov 29. PubMed
Sleep Regulation by Neurotensinergic Neurons in a Thalamo-Amygdala Circuit. Ma C, Zhong P, Liu D, Barger ZK, Zhou L, Chang WC, Kim B, Dan Y. Neuron. 2019 Jul 17;103(2):323-334.e7. doi: 10.1016/j.neuron.2019.05.015. Epub 2019 Jun 6. PubMed
In Vivo Single-Cell Genotyping of Mouse Cortical Neurons Transfected with CRISPR/Cas9. Steinecke A, Kurabayashi N, Hayano Y, Ishino Y, Taniguchi H. Cell Rep. 2019 Jul 9;28(2):325-331.e4. doi: 10.1016/j.celrep.2019.06.038. PubMed
Habenular TCF7L2 links nicotine addiction to diabetes. Duncan A, Heyer MP, Ishikawa M, Caligiuri SPB, Liu XA, Chen Z, Micioni Di Bonaventura MV, Elayouby KS, Ables JL, Howe WM, Bali P, Fillinger C, Williams M, O'Connor RM, Wang Z, Lu Q, Kamenecka TM, Ma'ayan A, O'Neill HC, Ibanez-Tallon I, Geurts AM, Kenny PJ. Nature. 2019 Oct;574(7778):372-377. doi: 10.1038/s41586-019-1653-x. Epub 2019 Oct 16. PubMed
New Additions to the CRISPR Toolbox: CRISPR-CLONInG and CRISPR-CLIP for Donor Construction in Genome Editing. Shola DTN, Yang C, Kewaldar VS, Kar P, Bustos V. CRISPR J. 2020 Apr;3(2):109-122. doi: 10.1089/crispr.2019.0062. PubMed
In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun. Riedel M, Berthelsen MF, Cai H, Haldrup J, Borre M, Paludan SR, Hager H, Vendelbo MH, Wagner EF, Bakiri L, Thomsen MK. Oncogene. 2021 Apr;40(13):2437-2447. doi: 10.1038/s41388-021-01724-6. Epub 2021 Mar 5. PubMed
CRISPR-mediated rapid generation of neural cell-specific knockout mice facilitates research in neurophysiology and pathology. Xiao D, Zhang W, Wang Q, Li X, Zhang Y, Rasouli J, Casella G, Ciric B, Curtis M, Rostami A, Zhang GX. Mol Ther Methods Clin Dev. 2021 Feb 18;20:755-764. doi: 10.1016/j.omtm.2021.02.012. eCollection 2021 Mar 12. PubMed
Loss of Quaking RNA binding protein disrupts the expression of genes associated with astrocyte maturation in mouse brain. Sakers K, Liu Y, Llaci L, Lee SM, Vasek MJ, Rieger MA, Brophy S, Tycksen E, Lewis R, Maloney SE, Dougherty JD. Nat Commun. 2021 Mar 9;12(1):1537. doi: 10.1038/s41467-021-21703-5. PubMed
Transgenic mice for in vivo epigenome editing with CRISPR-based systems. Gemberling MP, Siklenka K, Rodriguez E, Tonn-Eisinger KR, Barrera A, Liu F, Kantor A, Li L, Cigliola V, Hazlett MF, Williams CA, Bartelt LC, Madigan VJ, Bodle JC, Daniels H, Rouse DC, Hilton IB, Asokan A, Ciofani M, Poss KD, Reddy TE, West AE, Gersbach CA. Nat Methods. 2021 Aug;18(8):965-974. doi: 10.1038/s41592-021-01207-2. Epub 2021 Aug 2. PubMed
miR-183 and miR-96 orchestrate both glucose and fat utilization in skeletal muscle. Wang H, Ma M, Li Y, Liu J, Sun C, Liu S, Ma Y, Yan Y, Tang Z, Shen S, Yu J, Wu Y, Jiang J, Wang L, Jin ZB, Ying H, Li Y. EMBO Rep. 2021 Sep 6;22(9):e52247. doi: 10.15252/embr.202052247. Epub 2021 Aug 6. PubMed
Neuromodulatory control of inhibitory network arborization in the developing postnatal neocortex. Steinecke A, Bolton MM, Taniguchi H. Sci Adv. 2022 Mar 11;8(10):eabe7192. doi: 10.1126/sciadv.abe7192. Epub 2022 Mar 9. PubMed
Functionally distinct NPAS4-expressing somatostatin interneuron ensembles critical for motor skill learning. Yang J, Serrano P, Yin X, Sun X, Lin Y, Chen SX. Neuron. 2022 Oct 19;110(20):3339-3355.e8. doi: 10.1016/j.neuron.2022.08.018. Epub 2022 Sep 12. PubMed
Hedgehog-interacting protein acts in the habenula to regulate nicotine intake. Caligiuri SPB, Howe WM, Wills L, Smith ACW, Lei Y, Bali P, Heyer MP, Moen JK, Ables JL, Elayouby KS, Williams M, Fillinger C, Oketokoun Z, Lehmann VE, DiFeliceantonio AG, Johnson PM, Beaumont K, Sebra RP, Ibanez-Tallon I, Kenny PJ. Proc Natl Acad Sci U S A. 2022 Nov 15;119(46):e2209870119. doi: 10.1073/pnas.2209870119. Epub 2022 Nov 8. PubMed
PLD3 affects axonal spheroids and network defects in Alzheimer's disease. Yuan P, Zhang M, Tong L, Morse TM, McDougal RA, Ding H, Chan D, Cai Y, Grutzendler J. Nature. 2022 Dec;612(7939):328-337. doi: 10.1038/s41586-022-05491-6. Epub 2022 Nov 30. PubMed
A signalling pathway for transcriptional regulation of sleep amount in mice. Zhou R, Wang G, Li Q, Meng F, Liu C, Gan R, Ju D, Liao M, Xu J, Sang D, Gao X, Zhou S, Wu K, Sun Q, Guo Y, Wu C, Chen Z, Chen L, Shi B, Wang H, Wang X, Li H, Cai T, Li B, Wang F, Funato H, Yanagisawa M, Zhang EE, Liu Q. Nature. 2022 Dec;612(7940):519-527. doi: 10.1038/s41586-022-05510-6. Epub 2022 Dec 7. PubMed
Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina. Li S, Hu Y, Li Y, Hu M, Wang W, Ma Y, Cai Y, Wei M, Yao Y, Wang Y, Dong K, Gu Y, Zhao H, Bao J, Qiu Z, Zhang M, Hu X, Xue T. Sci Bull (Beijing). 2021 Feb 26;66(4):374-385. doi: 10.1016/j.scib.2020.09.008. Epub 2020 Sep 5. PubMed

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