CRISPR
Addgene's CRISPR collection includes plasmids and lentiviral preps for gene disruption, RNA base editing, pooled library screening, and more.
AAV
Addgene's ready-to-use AAV preparations include optogenetic, chemogenetic, and biosensor tools, as well as trial sizes for serotype testing.
Antibodies
Addgene's antibody collection includes ready-to-use recombinant antibodies expressed from plasmids.
All Plasmids
Addgene's repository contains 125,461 plasmids. Browse by gene, vector type, expression system, or depositing lab.
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pAAV-hSyn-fDIO-hM4D(Gi)-mCh…
Depositor: Ulrik Gether
Purpose: Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-fDIO-hM4D(Gi)-mCherry-WPREpA (#154867). Syn-driven, Flp-dependent hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.
Scientists Love Addgene
Addgene has been an exceptionally useful resource for us, both because they can be trusted to
supply our plasmids to other labs efficiently, and because we ourselves are constantly ordering
reagents of interest that other labs have deposited. Keep up the good work!
Dr. Anjana Rao
La Jolla Institute for Immunology
(La Jolla, CA)
Our optogenetic tools are sweeping throughout neuroscience, helping scientists figure out how the
brain works. Without Addgene helping provide these to the world, neuroscience would be moving at
a much slower pace.
Dr. Ed Boyden
Massachusetts Institute of Technology
(Cambridge, MA)
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