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pLX311-GFP-MEKDD

Plasmid

#194882

Purpose

Expression of dominant negative MEK1

Depositor

Sefi Rosenbluh

Article

Tuano et al Genome Biol. 2023 Mar 29;24(1):59. doi:

Insert

MEKDD (MAP2K1 Human)

Use

Lentiviral

Expression

Mammalian

Mutation

S218D, S222D

Promoter

E1Fa

Available Since

March 31, 2023

Availability

Academic Institutions and Nonprofits only

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RMCE wild type DNA-PKcs

Plasmid

#233911

Purpose

Low copy number provides expression of human DNA-PKcs

Depositor

Katheryn Meek

Article

Buehl et al Mol Cell. 2023 Mar 2;83(5):698-714.e4. d

Insert

dna-pkcs cDNA (PRKDC Human)

Expression

Mammalian

Available Since

April 9, 2025

Availability

Academic Institutions and Nonprofits only

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px330-Pten-2

Plasmid

#162552

Purpose

sgRNA targeting Pten

Depositor

Amaia Lujambio

Article

Molina-Sanchez et al Gastroenterology. 2020 Aug 16. pii: S001

Insert

sgRNA targeting Pten (Pten Mouse)

Expression

Mammalian

Mutation

None

Promoter

U6

Available Since

Feb. 17, 2021

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag YES1

Plasmid

#20665

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

YES1 (YES1 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only
pLKO.puro_shGLS

Plasmid

#110335

Purpose

shGLS (Target CAACTGGCCAAATTCAGTC), silence human GLS gene, puromycin selection

Depositor

Sandra Martha Gomes Dias

Article

Dias et al Oncogene. 2020 Jan;39(3):690-702. doi: 1

Insert

GLS glutaminase (GLS Human, Synthetic)

Use

Lentiviral and RNAi

Expression

Mammalian

Promoter

U6 (RNA PolIII)

Available Since

Feb. 23, 2021

Availability

Academic Institutions and Nonprofits only

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pET28b-SpRY-His

Plasmid

#179320

Purpose

Plasmid for bacterial expression and purification of SpRY-Cas9

Depositor

Julián Cerón, Miguel Angel Moreno-Mateos

Article

Vicencio et al Nat Commun. 2022 May 12;13(1):2601. doi:

Insert

Human codon-optimized Cas9 variant SpRY

Use

CRISPR

Tags

6xHis and SV40-NLS

Expression

Bacterial

Mutation

SpRY=A61R/L1111R/D1135L/S1136W/G1218K/E1219Q/ N13…

Available Since

May 12, 2022

Availability

Academic Institutions and Nonprofits only

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Anti-GABA(A)R, Delta [N151/3.3R]

Plasmid

#114515

Purpose

Mammalian Expression Plasmid of anti-GABA(A)R, Delta (Rat). Derived from hybridoma N151/3.3.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-GABA(A)R, Delta (Rattus norvegicus) recombinant mouse monoclonal antibody (Gabrd Mouse)

Expression

Mammalian

Promoter

dual CMV

Available Since

Oct. 1, 2018

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag MVK

Plasmid

#20616

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

MVK (MVK Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only
pcDNA3.1-CMV-PdCO-mScarlet

Plasmid

#198507

Purpose

Expresses optimized PdCO in frame with mScarlet under control of CMV promotor.

Depositor

Ofer Yizhar

Article

Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

Insert

PdCO

Tags

Rho1D4 and mScarlet

Expression

Mammalian

Promoter

CMV

Available Since

July 5, 2023

Availability

Academic Institutions and Nonprofits only

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Anti-Dopamine D3 receptor [N331/19R]

Plasmid

#114488

Purpose

Mammalian Expression Plasmid of anti-Dopamine D3 receptor (Human). Derived from hybridoma N331/19.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-Dopamine D3 receptor (Homo sapiens) recombinant mouse monoclonal antibody (DRD3 Mouse)

Expression

Mammalian

Promoter

dual CMV

Available Since

Sept. 21, 2018

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag PLK1

Plasmid

#20589

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

PLK1 (PLK1 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag PDK1

Plasmid

#20564

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

PDK1 (PDK1 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only

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Anti-Kv4.2 K+ Channel (External) [K57/1R]

Plasmid

#128622

Purpose

Mammalian Expression Plasmid of anti-Kv4.2 K+ Channel (External) (Human). Derived from hybridoma K57/1.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-Kv4.2 K+ Channel (External) (Human) recombinant mouse monoclonal antibody (KCND2 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available Since

Sept. 23, 2019

Availability

Academic Institutions and Nonprofits only

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Anti-LRRTM4 [N205B/22R]

Plasmid

#128636

Purpose

Mammalian Expression Plasmid of anti-LRRTM4 (Human). Derived from hybridoma N205B/22.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-LRRTM4 (Human) recombinant mouse monoclonal antibody (LRRTM4 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available Since

Oct. 1, 2019

Availability

Academic Institutions and Nonprofits only

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pAC1-V16-hGDNF

Plasmid

#122035

Purpose

AAV vector, pTet bidi (bidirectional tetracycline-responsive promoter) driving Tet-dependent rtTA and hGDNF expression

Depositor

Liliane Tenenbaum

Article

Chtarto et al Mol Ther Methods Clin Dev. 2016 Mar 30;5

Insert

hGDNF (GDNF Human)

Use

AAV

Available Since

April 17, 2019

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag PTK2

Plasmid

#20610

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

PTK2 (PTK2 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag PKN2

Plasmid

#20587

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

PKN2 (PKN2 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only
pWZL Neo Myr Flag HK2

Plasmid

#20501

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

HK2 (HK2 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only

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Anti-HCN4 [N114/10.1R]

Plasmid

#114506

Purpose

Mammalian Expression Plasmid of anti-HCN4 (Human). Derived from hybridoma N114/10.1.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-HCN4 (Homo sapiens) recombinant mouse monoclonal antibody (HCN4 Mouse)

Expression

Mammalian

Promoter

dual CMV

Available Since

Feb. 22, 2019

Availability

Academic Institutions and Nonprofits only

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pT3-EF1A-CCNE1

Plasmid

#162553

Purpose

Overexpression of CCNE1

Depositor

Amaia Lujambio

Article

Molina-Sanchez et al Gastroenterology. 2020 Aug 16. pii: S001

Insert

Overexpression of CCNE1 (CCNE1 Human)

Expression

Mammalian

Mutation

None

Promoter

EF1A

Available Since

Feb. 16, 2021

Availability

Academic Institutions and Nonprofits only

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Anti-TRPML3/Mucolipin-3 [N268/19R]

Plasmid

#114477

Purpose

Mammalian Expression Plasmid of anti-TRPML3/Mucolipin-3 (Human). Derived from hybridoma N268/19.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-TRPML3/Mucolipin-3 (Homo sapiens) recombinant mouse monoclonal antibody (MCOLN3 Mouse)

Expression

Mammalian

Promoter

dual CMV

Available Since

Sept. 20, 2018

Availability

Academic Institutions and Nonprofits only

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Anti-Kv2.1 K+ channel (External) [K39/25R]

Plasmid

#128620

Purpose

Mammalian Expression Plasmid of anti-Kv2.1 K+ channel (External) (Human). Derived from hybridoma K39/25.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-Kv2.1 K+ Channel (External) (Human) recombinant mouse monoclonal antibody (KCNB1 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available Since

Sept. 23, 2019

Availability

Academic Institutions and Nonprofits only

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Anti-Neurexin-1-Beta [N170A/26R]

Plasmid

#188207

Purpose

Mammalian Expression Plasmid of anti-Neurexin-1-Beta (Human). Derived from hybridoma N170A/26

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-Neurexin-1-Beta (Homo sapiens) recombinant mouse monoclonal antibody (NRXN1 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available Since

Nov. 1, 2022

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag PAK4

Plasmid

#20460

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

PAK4 (PAK4 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only
Anti-Cavbeta2 Ca2+ channel [N8B/1R]

Plasmid

#149458

Purpose

Mammalian Expression Plasmid of anti-Cavbeta2 Ca2+ channel (Rat). Derived from hybridoma N8B/1.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

Mammalian Expression of anti-Cavbeta2 Ca2+ channel (Rat) recombinant mouse monoclonal antibody (Cacnb2 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available Since

June 26, 2020

Availability

Academic Institutions and Nonprofits only

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Anti-Clcn4 [N222/6R]

Plasmid

#114474

Purpose

Mammalian Expression Plasmid of anti-Clcn4 (Human). Derived from hybridoma N222/6.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-Clcn4 (Homo sapiens) recombinant mouse monoclonal antibody (CLCN4 Mouse)

Use

Affinity Reagent/ Antibody

Expression

Mammalian

Promoter

dual CMV

Available Since

Sept. 20, 2018

Availability

Academic Institutions and Nonprofits only

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MSCV-ASNS-OE-IRES-Thy1.1

Plasmid

#192947

Purpose

Asparagine synthetase overexpression in murine cells

Depositor

Ping-Chih Ho

Article

Fernandez-Garcia et al Cell Rep. 2022 Nov 15;41(7):111639. doi:

Insert

Asparagine synthetase (Asns Mouse)

Use

Retroviral

Expression

Mammalian

Promoter

5'LTR

Available Since

Jan. 10, 2023

Availability

Academic Institutions and Nonprofits only

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Anti-Neurexin-1-Beta [N170A/1.1R]

Plasmid

#114530

Purpose

Mammalian Expression Plasmid of anti-Neurexin-1-Beta (Human). Derived from hybridoma N170A/1.1.

Depositor

James Trimmer

Article

Andrews et al eLife. 2019 Jan 22;8. pii: 43322. doi: 1

Insert

anti-Neurexin-1-Beta (Homo sapiens) recombinant mouse monoclonal antibody (NRXN1 Mouse)

Expression

Mammalian

Promoter

dual CMV

Available Since

May 29, 2019

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag PRKAA1

Plasmid

#20595

Depositor

William Hahn, Jean Zhao

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

PRKAA1 (PRKAA1 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Available Since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only
pPB-CAG-ARID1A-deltaIDR1-FLAG

Plasmid

#242210

Purpose

Expression of human ARID1A ∆IDR1 (deletion of a.a. 2–970) using piggyBac transposition

Depositor

Courtney Hodges

Article

Chan et al Mol Cell. 2025 Jul 15:S1097-2765(25)0057

Insert

ARID1A (ARID1A Human)

Use

Piggybac

Tags

FLAG

Expression

Mammalian

Mutation

Deleted IDR1 from ARID1A (deletion of a.a. 2–970)

Promoter

CAG

Available Since

Sept. 9, 2025

Availability

Academic Institutions and Nonprofits only

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