We narrowed to 2,472 results for: GCG

1. Lenti-sgArid2#2/Cre

   Plasmid

   #173576

   Purpose

   Expresses a Arid2-targeting gRNA and Cre-recombinase

   Depositor

   Charles Swanton

   Article

   Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

   Insert

   gRNA targeting Arid2 (Arid2 Mouse)
   

   Use

   CRISPR, Cre/Lox, and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   June 7, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. px335 Mettl14 sgRNA #1

   Plasmid

   #61515

   Purpose

   encodes sgRNA sequence for targeting mouse Mettl14 locus (Cas9-Nickase strategy)

   Depositor

   Jacob Hanna

   Article

   Geula et al Science. 2015 Feb 27;347(6225):1002-6. d

   Insert

   gcggcagctcctagctcagc
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Jan. 6, 2015

   Availability

   Academic Institutions and Nonprofits only

3. shERK2b-mlpx-neo

   Plasmid

   #65231

   Purpose

   encodes a shRNA against ERK2

   Depositor

   Gerardo Ferbeyre

   Article

   Deschenes-Simard et al Genes Dev. 2013 Apr 15;27(8):900-15. doi

   Insert

   shRNA against ERK2 (MAPK1 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   PGK

   Available since

   Aug. 12, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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4. pXPR_BRD051-sgCh2-2

   Plasmid

   #125775

   Purpose

   constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control) and S. pyogenes Cas9

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgCh2-2
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. LCV2_PSMD1_sgRNA_1

   Plasmid

   #155091

   Purpose

   lentiviral plasmid expressing Cas9 and gRNA targeting PSMD1 (core essential gene)

   Depositor

   Jason Moffat

   Article

   Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

   Insert

   PSMD1_sgRNA_1 (PSMD1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6 promoter

   Available since

   Aug. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLentiCMVblast_SLC38A2_N82A

   Plasmid

   #156181

   Purpose

   CMV-driven expression of sgRNA-resistant SLC38A2 N82A mutant cDNA.

   Depositor

   Alec Kimmelman

   Article

   Parker et al Cancer Discov. 2020 Apr 27. pii: 2159-82

   Insert

   SLC38A2 (SLC38A2 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Silent mutations to prevent targeting by sgRNA: T…

   Promoter

   CMV

   Available since

   Aug. 20, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-AICD-NES-IRES-hrGFP

   Plasmid

   #107544

   Purpose

   AAV-mediated expression of AICD (last 50 amino acids of APP) with Nuclear Export Signal (NES: CTCCCTCCACTAGAGCGACTAACCTTA) at C-term end and IRES-mediated co-expression of hrGFP

   Depositor

   Hélène Marie

   Article

   Pousinha et al Elife. 2017 Jul 6;6. doi: 10.7554/eLife.

   Insert

   AICD-NES (APP Human)
   

   Use

   AAV

   Tags

   Expression

   Mutation

   None

   Promoter

   CMV

   Available since

   May 2, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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8. pInducer20_SLC38A2_N82A

   Plasmid

   #156183

   Purpose

   Dox-inducible expression of sgRNA-resistant SLC38A2 N82A mutant cDNA.

   Depositor

   Alec Kimmelman

   Article

   Parker et al Cancer Discov. 2020 Apr 27. pii: 2159-82

   Insert

   SLC38A2 (SLC38A2 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Silent mutations to prevent targeting by sgRNA: T…

   Promoter

   TRE

   Available since

   Aug. 20, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. HK2 gRNA (BRDN0001162355)

   Plasmid

   #76311

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human HK2

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   HK2 (HK2, HOOK2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. LCV2_mCherry_PSMD1_sgRNA_1

    Plasmid

    #155107

    Purpose

    lentiviral plasmid expressing mCherry, Cas9 and a gRNA targeting PSMD1 (core essential gene)

    Depositor

    Jason Moffat

    Article

    Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

    Insert

    PSMD1_sgRNA_1 (PSMD1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6 promoter

    Available since

    Aug. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. ERBB3 gRNA (BRDN0001147186)

    Plasmid

    #77479

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ERBB3

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ERBB3 (ERBB3 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. TET-pLKO.1 PURO shGDF11 #1

    Plasmid

    #83083

    Purpose

    Lentiviral shRNA vector for inducible knockdown of human GDF11 (cross reacts with mouse Gdf11)

    Depositor

    Kevin Janes

    Article

    Bajikar et al Dev Cell. 2017 Nov 20;43(4):418-435.e13.

    Insert

    shGDF11 (GDF11, Gdf11 Human, Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 28, 2019

    Availability

    Academic Institutions and Nonprofits only

13. ABL1 gRNA (BRDN0001145259)

    Plasmid

    #77734

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ABL1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ABL1 (ABL1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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14. sgEGFR(B)

    Plasmid

    #85565

    Purpose

    Expresses sgRNA targeting human EGFR around codon T790

    Depositor

    Luca Grumolato

    Article

    Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

    Insert

    epidermal growth factor receptor (EGFR Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 8, 2017

    Availability

    Academic Institutions and Nonprofits only

15. CSNK1E gRNA (BRDN0001147318)

    Plasmid

    #77977

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CSNK1E

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CSNK1E,LOC400927-CSNK1E (CSNK1E, TPTEP2-CSNK1E Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pKLV2-U6gRNA5(hIKBKG_1k)-PGKpuro2ABFP-W

    Plasmid

    #208410

    Purpose

    Lentiviral gRNA plasmid targeting human IKBKG gene, co-expression of BFP tag

    Depositor

    Sok Ching Cheong

    Article

    Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

    Insert

    IKBKG (IKBKG Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    N/A

    Promoter

    human U6

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pKLV2-U6gRNA5(hIKBKG_2m)-PGKpuro2ABFP-W

    Plasmid

    #208411

    Purpose

    Lentiviral gRNA plasmid targeting human IKBKG gene, co-expression of BFP tag

    Depositor

    Sok Ching Cheong

    Article

    Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

    Insert

    IKBKG (IKBKG Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    N/A

    Promoter

    human U6

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. KHC065 pBABE pU6 BRD2 K1-2C

    Plasmid

    #231712

    Purpose

    KHC065 (pBABE pU6 BRD2 K1-2C), gRNA and cas9D10A mammalian expression vector for CRISPR mediated cutting of BRD2 at the N-terminus, use with KHC064

    Depositor

    Alessio Ciulli

    Article

    Bond et al J Med Chem. 2021 Oct 28;64(20):15477-155

    Insert

    gRNA for Brd2 and Cas9D10A (BRD2 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. KHC064 pX335 BRD2 K1-1a

    Plasmid

    #231711

    Purpose

    KHC064 (pX335 BRD2 K1-1a), gRNA and cas9D10A mammalian expression vector for CRISPR mediated cutting of BRD2 at the N-terminus, use with KHC065

    Depositor

    Alessio Ciulli

    Article

    Bond et al J Med Chem. 2021 Oct 28;64(20):15477-155

    Insert

    gRNA for Brd2 and Cas9D10A (BRD2 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. sgLATS1/2-1

    Plasmid

    #229431

    Purpose

    knockout of LATS1 and LATS2

    Depositor

    Christopher Vakoc

    Article

    Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

    Insert

    sgLATS1/2-1 (LATS1, LATS2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6;bU6;EFS

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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