We narrowed to 1,038 results for: plko

1. pLKO.puro_shHuR 3UTR

   Plasmid

   #110414

   Purpose

   TRCN0000276186 (Target TTGTTAGTGTACAACTCATTT), silence human ELAVL1 (HuR) gene, puromycin selection

   Depositor

   Sandra Martha Gomes Dias

   Insert

   ELAVL1 (HuR)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6 (RNA PolIII)

   Available since

   Feb. 23, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLKO.1 shFEN3

   Plasmid

   #17922

   Depositor

   Sheila Stewart

   Article

   Saharia et al Curr Biol. 2008 Apr 8. 18(7):496-500.

   Insert

   shFEN3
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 11, 2008

   Availability

   Academic Institutions and Nonprofits only

3. pLKO-PHB-6

   Plasmid

   #122232

   Purpose

   Expresses shRNA targeting the coding sequence of human PHB

   Depositor

   Alex Kentsis

   Article

   Ortiz et al JCI Insight. 2019 Aug 8;4(15). pii: 1270

   Insert

   shRNA targeting PHB (see partial depositor seq) (PHB1 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 8, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pLKO_S.V5.HA_NGFR

   Plasmid

   #158339

   Purpose

   Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

   Depositor

   Brian Brown

   Article

   Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

   Insert

   Pro-Code Tagged human dNGFR (NGFR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   S.V5.HA

   Expression

   Mutation

   Truncation of the signaling domain

   Promoter

   EF1a

   Available since

   Sept. 3, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLKO_Ollas.AU1.C_NGFR

   Plasmid

   #158314

   Purpose

   Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

   Depositor

   Brian Brown

   Article

   Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

   Insert

   Pro-Code Tagged human dNGFR (NGFR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Ollas.AU1.C

   Expression

   Mutation

   Truncation of the signaling domain

   Promoter

   EF1a

   Available since

   Sept. 3, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLKO_HA.AU1.V5_NGFR

   Plasmid

   #158235

   Purpose

   Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

   Depositor

   Brian Brown

   Article

   Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

   Insert

   Pro-Code Tagged human dNGFR (NGFR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   HA.AU1.V5

   Expression

   Mutation

   Truncation of the signaling domain

   Promoter

   EF1a

   Available since

   Sept. 3, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLKO.1P MUTYH_2

   Plasmid

   #160786

   Purpose

   Suppress MUTYH

   Depositor

   Richard Possemato

   Article

   Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

   Insert

   shMUTYH_2
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Oct. 29, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLKO.1P MUTYH_1

   Plasmid

   #160785

   Purpose

   Suppress MUTYH

   Depositor

   Richard Possemato

   Article

   Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

   Insert

   shMUTYH_1
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Oct. 29, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLKO-sh-Myocardin

   Plasmid

   #100769

   Purpose

   Lentiviral expression of shRNA targeting MYOCD

   Depositor

   Joseph Gordon

   Article

   Mughal et al Cell Death Differ. 2018 Mar 6. pii: 10.1

   Insert

   Lenti-sh-Myocardin
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Sept. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLKO.1P shISCU

    Plasmid

    #102972

    Purpose

    Suppression of ISCU

    Depositor

    Richard Possemato

    Article

    Alvarez et al Nature. 2017 Nov 22. doi: 10.1038/nature

    Insert

    shISCU
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Nov. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. plko_TRE3G_Myc-Sox9WT_PGKpuroR

    Plasmid

    #203962

    Purpose

    Dox inducible WT SOX9 with myc tag

    Depositor

    Elaine Fuchs

    Article

    Yang et al Nat Cell Biol. 2023 Jul 24. doi: 10.1038

    Insert

    SOX9 (Sox9 Mouse)
    

    Use

    Lentiviral

    Tags

    myc

    Expression

    Mutation

    Promoter

    TRE3G

    Available since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. plko_TRE3G_Myc-Sox9HMGonlySTOP_PGKpuroR

    Plasmid

    #203963

    Purpose

    Dox inducible myc tag truncated SOX9 without trans-activating domain (noTA)

    Depositor

    Elaine Fuchs

    Article

    Yang et al Nat Cell Biol. 2023 Jul 24. doi: 10.1038

    Insert

    SOX9-noTA (Sox9 Mouse)
    

    Use

    Lentiviral

    Tags

    myc

    Expression

    Mutation

    the TA domain is truncated

    Promoter

    TRE3G

    Available since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. plko_TRE3G_nlsMyc-Sox9HMGtruncation_PGKpuroR

    Plasmid

    #203964

    Purpose

    Dox inducible myc tag truncated SOX9 without DNA-binding domain (noHMG)

    Depositor

    Elaine Fuchs

    Article

    Yang et al Nat Cell Biol. 2023 Jul 24. doi: 10.1038

    Insert

    SOX9-noHMG (Sox9 Mouse)
    

    Use

    Lentiviral

    Tags

    myc

    Expression

    Mutation

    the HMG domain is truncated

    Promoter

    TRE3G

    Available since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pLKO.1-PPP2R5A-1

    Plasmid

    #179352

    Purpose

    shRNA suppression

    Depositor

    William Hahn

    Article

    Sablina et al Cancer Res. 2010 Dec 15;70(24):10474-84.

    Insert

    B56α
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Age1

    Available since

    Feb. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pLKO.1-PPP2R5C-2

    Plasmid

    #179356

    Purpose

    shRNA suppression

    Depositor

    William Hahn

    Article

    Sablina et al Cancer Res. 2010 Dec 15;70(24):10474-84.

    Insert

    B56γ
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Age1

    Available since

    Feb. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pLKO.1-PPP2R3B-1

    Plasmid

    #179360

    Purpose

    shRNA suppression

    Depositor

    William Hahn

    Article

    Sablina et al Cancer Res. 2010 Dec 15;70(24):10474-84.

    Insert

    PR48
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Age1

    Available since

    Feb. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pLKO_NWS.S.V5_mCherry-NLS

    Plasmid

    #178281

    Purpose

    Nuclear Protein Barcode (nPC) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables spatial detection of CRISPR screens.

    Depositor

    Brian Brown

    Article

    Dhainaut et al Cell. 2022 Mar 10. pii: S0092-8674(22)00

    Insert

    nPC Tagged mCherry-NLS
    

    Use

    Lentiviral

    Tags

    NWS.S.V5 and Nuclear Localization Signal

    Expression

    Mutation

    Promoter

    eF1a

    Available since

    Jan. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLKO_NWS.Ollas.V5_mCherry-NLS

    Plasmid

    #178280

    Purpose

    Nuclear Protein Barcode (nPC) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables spatial detection of CRISPR screens.

    Depositor

    Brian Brown

    Article

    Dhainaut et al Cell. 2022 Mar 10. pii: S0092-8674(22)00

    Insert

    nPC Tagged mCherry-NLS
    

    Use

    Lentiviral

    Tags

    NWS.Ollas.V5 and Nuclear Localization Signal

    Expression

    Mutation

    Promoter

    eF1a

    Available since

    Jan. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLKO_HSV.NWS.V5_mCherry-NLS

    Plasmid

    #178275

    Purpose

    Nuclear Protein Barcode (nPC) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables spatial detection of CRISPR screens.

    Depositor

    Brian Brown

    Article

    Dhainaut et al Cell. 2022 Mar 10. pii: S0092-8674(22)00

    Insert

    nPC Tagged mCherry-NLS
    

    Use

    Lentiviral

    Tags

    HSV.NWS.V5 and Nuclear Localization Signal

    Expression

    Mutation

    Promoter

    eF1a

    Available since

    Jan. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLKO_HSV.NWS.VSVg_mCherry-NLS

    Plasmid

    #178274

    Purpose

    Nuclear Protein Barcode (nPC) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables spatial detection of CRISPR screens.

    Depositor

    Brian Brown

    Article

    Dhainaut et al Cell. 2022 Mar 10. pii: S0092-8674(22)00

    Insert

    nPC Tagged mCherry-NLS
    

    Use

    Lentiviral

    Tags

    HSV.NWS.VSVg and Nuclear Localization Signal

    Expression

    Mutation

    Promoter

    eF1a

    Available since

    Jan. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge