We narrowed to 25,213 results for: grna

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sgPBRM1-1- LentiCRISPRv2

Plasmid

#107403

Purpose

Lentiviral expression of Cas9 and gRNA targeting PBRM1

Depositor

William Kaelin

Publication

Gao et al Proc Natl Acad Sci U S A. 2017 Jan 31;11

Insert

gRNA targeting PBRM1 (PBRM1 Human)

Use

Lentiviral

Available since

June 14, 2018

Availability

Academic Institutions and Nonprofits only

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Lenti-sgSetd2#1/Cre

Plasmid

#89649

Purpose

Expresses a Setd2-targeting gRNA and Cre-recombinase

Depositor

Monte Winslow

Publication

Rogers et al Nat Methods. 2017 May 22. doi: 10.1038/n

Insert

gRNA targeting Setd2 (Setd2 Mouse)

Use

Cre/Lox and Lentiviral

Expression

Mammalian

Available since

July 19, 2017

Availability

Academic Institutions and Nonprofits only

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pORANGE GFP-Grin1 KI

Plasmid

#131485

Purpose

Endogenous tagging of GluN1: N-terminal (amino acid position: A20)

Depositor

Harold MacGillavry

Publication

Willems et al PLoS Biol. 2020 Apr 10;18(4):e3000665. d

Insert

gRNA and GFP donor (Grin1, Grin1 Mouse, Rat)

Expression

Mammalian

Promoter

U6 and Cbh

Available since

Sept. 19, 2019

Availability

Academic Institutions and Nonprofits only

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pXPR_206

Plasmid

#96920

Purpose

for SaCas9 knockout, lentiviral expression of S. aureus Cas9 (SauCas9) and gRNA scaffold

Depositor

John Doench, David Root

Publication

Najm et al Nat Biotechnol. 2018 Feb;36(2):179-189.

Type

Empty backbone

Use

Lentiviral

Expression

Mammalian

Available since

June 28, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

3 Articles

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pJZC74

Plasmid

#62342

Purpose

sgRNA + 1x COM with COM-KRAB effector for mammalian cells

Depositor

Wendell Lim, Stanley Qi

Publication

Zalatan et al Cell. 2014 Dec 18. pii: S0092-8674(14)01

Inserts

sgRNA + 1x COM binding module
COM-KRAB

Use

Lentiviral

Tags

KRAB

Expression

Mammalian

Mutation

Targets sv40 promoter, sequence: GAATAGCTCAGAGGCC…

Promoter

CMV and U6

Available since

April 2, 2015

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pADH139

Plasmid

#90987

Purpose

NAT-marked "empty" gRNA construct for use in gRNA expression cassette stitching PCR; use with pADH110 to generate target-specific part 2 of 2 for C.mal LEUpOUT CRISPR system.

Depositor

Aaron Hernday

Publication

Nguyen et al mSphere. 2017 Apr 26;2(2):e00149-17. doi

Insert

gRNA conserved, C, mal LEU2 2 of 2

Use

CRISPR

Available since

June 5, 2017

Availability

Academic Institutions and Nonprofits only

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pLenti-L3US2-RFP-HDAC3

Plasmid

#83966

Purpose

Lentiviral CRISPR HDAC3 dual gRNA targeting vector

Depositor

Eleanor Chen

Insert

HDAC3 dual gRNAs (HDAC3 Human)

Use

Lentiviral

Expression

Mammalian

Promoter

U6

Available since

Dec. 6, 2016

Availability

Academic Institutions and Nonprofits only

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pADH139

Plasmid

#90987

Purpose

NAT-marked "empty" gRNA construct for use in gRNA expression cassette stitching PCR; use with pADH110 to generate target-specific part 2 of 2 for C.mal LEUpOUT CRISPR system.

Depositor

Aaron Hernday

Publication

Nguyen et al mSphere. 2017 Apr 26;2(2):e00149-17. doi

Insert

gRNA conserved, C, mal LEU2 2 of 2

Use

CRISPR

Available since

June 5, 2017

Availability

Academic Institutions and Nonprofits only

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Lenti-sgSetd2#1/Cre

Plasmid

#89649

Purpose

Expresses a Setd2-targeting gRNA and Cre-recombinase

Depositor

Monte Winslow

Publication

Rogers et al Nat Methods. 2017 May 22. doi: 10.1038/n

Insert

gRNA targeting Setd2 (Setd2 Mouse)

Use

Cre/Lox and Lentiviral

Expression

Mammalian

Available since

July 19, 2017

Availability

Academic Institutions and Nonprofits only

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sgPBRM1-2- LentiCRISPRv2

Plasmid

#107404

Purpose

Lentiviral expression of Cas9 and gRNA targeting PBRM1

Depositor

William Kaelin

Publication

Gao et al Proc Natl Acad Sci U S A. 2017 Jan 31;11

Insert

gRNA targeting PBRM1 (PBRM1 Human)

Use

Lentiviral

Available since

June 14, 2018

Availability

Academic Institutions and Nonprofits only

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Lenti-sgLats1#2/Cre

Plasmid

#173600

Purpose

Expresses a Lats1-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Publication

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Lats1 (Lats1 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgLats1#1/Cre

Plasmid

#173599

Purpose

Expresses a Lats1-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Publication

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Lats1 (Lats1 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgPole#2/Cre

Plasmid

#173610

Purpose

Expresses a Pole-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Publication

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Pole (Pole Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available since

June 7, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgPole#1/Cre

Plasmid

#173609

Purpose

Expresses a Pole-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Publication

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Pole (Pole Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available since

May 12, 2022

Availability

Academic Institutions and Nonprofits only

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ACE2 g2

Plasmid

#153012

Purpose

A guide RNA targeting ACE2 in a lentiviral plasmid co-expressing mCherry

Depositor

Jason Sheltzer

Insert

ACE2 gRNA (ACE2 Human)

Use

CRISPR and Lentiviral

Tags

mCherry

Available since

June 1, 2020

Availability

Academic Institutions and Nonprofits only

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OA-1055J

Plasmid

#200251

Purpose

pBac-U6-gRNA(Intersex)-3xp3-tdTomato

Depositor

Omar Akbari

Publication

Li et al bioRxiv. 2023 Nov 15:2023.04.18.537404.

Insert

2 gRNAs targeting Intersex gene

Expression

Insect

Available since

May 12, 2023

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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AOI-WT-Cas9-sg-mouse Suz12-F2-GFP

Plasmid

#91882

Purpose

Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Suz12

Depositor

Martine Roussel

Publication

Vo et al Cell Rep. 2017 Mar 21;18(12):2907-2917.

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

gRNA targeting Suz12 (Suz12 Mouse)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available since

June 26, 2017

Availability

Academic Institutions and Nonprofits only
sgPBRM1-2- LentiCRISPRv2

Plasmid

#107404

Purpose

Lentiviral expression of Cas9 and gRNA targeting PBRM1

Depositor

William Kaelin

Publication

Gao et al Proc Natl Acad Sci U S A. 2017 Jan 31;11

Insert

gRNA targeting PBRM1 (PBRM1 Human)

Use

Lentiviral

Available since

June 14, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
AOI-WT-Cas9-sg-mouse Suz12-F2-GFP

Plasmid

#91882

Purpose

Expresses 3xFLAG-Cas9 and a gRNA targeting mouse Suz12

Depositor

Martine Roussel

Publication

Vo et al Cell Rep. 2017 Mar 21;18(12):2907-2917.

Insert

gRNA targeting Suz12 (Suz12 Mouse)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available since

June 26, 2017

Availability

Academic Institutions and Nonprofits only
pOTTC1088 - pAAV TH gRNA A+B pair EF1a EGFP

Plasmid

#113155

Purpose

An AAV vector that expresses guide RNAs targeting rat TH and expresses EGFP reporter

Depositor

Brandon Harvey

Publication

Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

Insert

Two gRNAs for rat TH

Use

AAV and CRISPR

Expression

Mammalian

Promoter

mU6 and hU6

Available since

March 7, 2019

Availability

Academic Institutions and Nonprofits only

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