Purpose
Mammalian Expression, Retroviral vector that encodes a 3LA mutant of 53BP1 that disrupts three RIF1-binding motifs and abolishes the 53BP1-dependent recruitment of RIF1 to DNA double-strand breaks.
Tags
Flag tag, HA tag, and tetracysteine tag
Mutation
L175A, L517A, and L693A
Available Since
July 7, 2022
Availability
Industry, Academic Institutions, and Nonprofits