We narrowed to 7,246 results for: CIT

1. Venus-tBid-2E-pEGFP-C1

   Plasmid

   #166747

   Purpose

   Express Venus fused to the N-terminus of the Bcl-2 family protein, tBid with mutation to 2 positions in the BH3 domain

   Depositor

   David Andrews

   Article

   Osterlund et al Sci Adv. 2022 Apr 22;8(16):eabm7375. doi

   Insert

   tBid-2E (Bid Mouse)
   

   Use

   Tags

   Venus

   Expression

   Mammalian

   Mutation

   2 hydrophobic residues in the BH3 region mutated …

   Promoter

   CMV

   Available since

   March 29, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. 61427-sgHtt_10

   Plasmid

   #157861

   Purpose

   Expresses a sgRNA targeting mouse Htt promoter for gene activation using the SAM system

   Depositor

   Xinyu Zhao

   Article

   Shen et al Nat Neurosci. 2019 Mar;22(3):386-400. do

   Insert

   Htt (Htt Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Feb. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. 61427-sgHtt_6

   Plasmid

   #157860

   Purpose

   Expresses a sgRNA targeting mouse Htt promoter for gene activation using the SAM system

   Depositor

   Xinyu Zhao

   Article

   Shen et al Nat Neurosci. 2019 Mar;22(3):386-400. do

   Insert

   Htt (Htt Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Feb. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. pGEX-4T-3 SIRT1-NTerm Exon1-Exon3

   Plasmid

   #105681

   Purpose

   Bacterial Expression construct of N terminus of SIRT1: Exon1-Exon3 (deltaExon2)

   Depositor

   Ullas Kolthur-Seetharam

   Article

   Deota et al Cell Rep. 2017 Mar 28;18(13):3069-3077.

   Insert

   SIRT1-NTerm: Exon1-Exon3 (Sirt1 Mouse)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Synonymous base changes not affecting the protein…

   Promoter

   tac_Promoter

   Available since

   April 6, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pGEX-4T-3- SIRT1-NTerm Exon1-Exon2-Exon3

   Plasmid

   #105680

   Purpose

   Bacterial Expression construct of N terminus of SIRT1: Exon1-Exon2-Exon3

   Depositor

   Ullas Kolthur-Seetharam

   Article

   Deota et al Cell Rep. 2017 Mar 28;18(13):3069-3077.

   Insert

   SIRT1-NTerm: Exon1-Exon2-Exon3 (Sirt1 Mouse)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Synonymous base changes not affecting the protein…

   Promoter

   tac_Promoter

   Available since

   April 6, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. MoFGFR31c-ires neo

   Plasmid

   #86496

   Purpose

   mamalian cell expression of FGFR3-FGFR1 chimera

   Depositor

   David Ornitz

   Article

   Ornitz et al J Biol Chem. 1996 Jun 21;271(25):15292-7

   Insert

   FgfrR3-1 IIIc 15C7 (Fgfr1, Fgfr3 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   FGFR3-FGFR1 chimera

   Promoter

   Moloney murine leukemia virus LTR

   Available since

   Feb. 14, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. MoFGFR31b-ires neo

   Plasmid

   #86495

   Purpose

   mamalian cell expression of FGFR3-FGFR1 chimera

   Depositor

   David Ornitz

   Article

   Ornitz et al J Biol Chem. 1996 Jun 21;271(25):15292-7

   Insert

   FgfrR31 IIIb 15C8 (Fgfr3, Fgfr1 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   FGFR3-FGFR1 chimera

   Promoter

   Moloney murine leukemia virus LTR

   Available since

   Feb. 2, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. Mouse Chromatin Regulator Library

   Pooled Library

   #200011

   Purpose

   CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

   Depositor

   Robert Manguso, Bradley Bernstein, Gabriel Griffin

   Article

   Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

9. pLVX-UbC-rtTA-Ngn2:2A:EGFP

   Plasmid

   #127288

   Purpose

   all-in-one inducible LV expression construct for Ngn2:2A:EGFP (aka. UNG; for direct neuronal conversion)

   Depositor

   Fred Gage

   Article

   Schafer et al Nat Neurosci. 2019 Feb;22(2):243-255. do

   Insert

   Ngn2:2A:Ascl1 (NEUROG2 Human)
   

   Use

   Lentiviral

   Tags

   Ngn2 and EGFP linked via 2A

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 6, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. Rasgrf2-2A-dCre targeting vector

    Plasmid

    #61573

    Purpose

    Target a DHFR-destabilized Cre recombinase gene to the stop codon of the mouse Rasgrf2 gene

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    Rasgrf2-2A-dCre (Rasgrf2 P1 bacteriophage, Mouse)
    

    Use

    Cre/Lox and Mouse Targeting

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 31, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAAV-Syn-Chronos-tdTomato

    Plasmid

    #62726

    Purpose

    AAV-mediated expression of Chronos-tdTomato under the Syn promoter. Using bGHpA signal. tdTomato has codons varied between the first and second tandem repeats to reduce recombination.

    Depositor

    Edward Boyden

    Article

    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

    Insert

    Chronos-tdTomato
    

    Use

    AAV

    Tags

    tdTomato

    Expression

    Mammalian

    Mutation

    Promoter

    human synapsin promoter

    Available since

    April 30, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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12. pcDNA 3.1 KBTBD4 R313PRR

    Plasmid

    #184629

    Purpose

    Mammalian expression vector with N-terminal Flag for KBTBD4 R313PRR expression in mammalian cells

    Depositor

    Vincenzo D'Angiolella

    Article

    Chen et al Cell Death Differ. 2022 Apr 4. pii: 10.1

    Insert

    N-terminal 3xFlag tagged KBTBD4 R313PRR (KBTBD4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    R313PRR

    Promoter

    CMV

    Available since

    June 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-TNT4-Zfr-P2A-HA-luciferase-3xMIR122

    Plasmid

    #223184

    Purpose

    Plasmid containing the Zfr/Firefly luciferase/3xMIR122 cassette. Translation of luciferase is controlled by splicing modulation of the Zfr specifically in cardiomyocytes by risdiplam in vivo.

    Depositor

    Yuxuan Guo

    Article

    Chen et al Nat Cardiovasc Res. 2025 Jun 13. doi: 10

    Inserts

    luciferase (LOC116160065 firefly)
    mir122 (Mir122 Mouse)
    

    Use

    AAV

    Tags

    HA and engineered P2A

    Expression

    Mutation

    Promoter

    TNNT2

    Available since

    June 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-Syn-FLEX-rc [ChrimsonR-GFP]

    Plasmid

    #84480

    Purpose

    AAV-mediated expression of ChrimsonR-GFP under the Syn promoter, in floxed/reversed (Cre-dependent) manner. Using bGHpA signal.

    Depositor

    Edward Boyden

    Article

    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

    Insert

    ChrimsonR-GFP
    

    Use

    AAV

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Chrimson K176R mutant

    Promoter

    human synapsin promoter

    Available since

    April 25, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-FLEX-P301L Tau

    Plasmid

    #176267

    Purpose

    This AAV plasmid vector expresses human 2N4R microtubule-associated protein tau with P301L mutation.

    Depositor

    Tsuneya Ikezu

    Article

    You et al Neuroscience. 2019 Dec 1;422:65-74. doi:

    Insert

    Flex-P301L tau (MAPT )
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. pDONR221_SLC25A13

    Plasmid

    #132038

    Purpose

    Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

    Insert

    SLC25A13 (SLC25A13 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 1, 2019

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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17. AAV phSyn1(S)-FlpO-bGHpA

    Plasmid

    #51669

    Purpose

    Can be used to generate AAV virus that will express the FlpO recombinase gene in neurons from the synapsin promoter.

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Has Service

    AAV Retrograde

    Insert

    FlpO recombinase gene
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hSyn1

    Available since

    May 2, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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18. AAV phSyn1-FSF-FLEX-ChR2(H134R)-EYFP-WPRE-bGHpA

    Plasmid

    #65454

    Purpose

    Can be used to generate AAV virus that will express the ChR2(H134R)-EYFP channelrhodopsin fusion protein in neurons under intersectional control by Flp and Cre recombinases

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    ChR2(H134R)-EYFP
    

    Use

    AAV

    Tags

    EYFP

    Expression

    Mutation

    H134R variant

    Promoter

    hSyn1

    Available since

    July 7, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCIG-FGF13A

    Plasmid

    #220793

    Purpose

    To express the human FGF13 isoform 1(FGF13A) in mammalian cells together with EGFP

    Depositor

    Pierre Vanderhaeghen

    Article

    Libe-Philippot et al Cell. 2023 Dec 21;186(26):5766-5783.e25.

    Insert

    FGF13 (FGF13 Human)
    

    Use

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pET-His6-FnCas9GFP

    Plasmid

    #130966

    Purpose

    expression of FnCas9-GFP in bacterial cells

    Depositor

    Debojyoti Chakraborty

    Article

    Acharya et al Proc Natl Acad Sci U S A. 2019 Oct 15;11

    Insert

    HA-NLS-FnCas9
    

    Use

    CRISPR

    Tags

    6xHis-mEGFP-TEV-HA-NLS

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available since

    Nov. 7, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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