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pBABEpuro-ERBB2 E321G

Plasmid

#40981

Depositor

Matthew Meyerson

Article

Greulich et al Proc Natl Acad Sci U S A. 2012 Sep 4;109

Insert

ERBB2 (ERBB2 Human)

Use

Retroviral

Expression

Mammalian

Mutation

E321G

Available Since

Nov. 6, 2012

Availability

Academic Institutions and Nonprofits only
CRISPRi sgSOS1-2

Plasmid

#253093

Purpose

CRISPRi single-guide against SOS1

Depositor

Harish Vasudevan

Article

Vasudevan et al Proc Natl Acad Sci U S A. 2025 Jul 8;122

Insert

SOS1 (SOS1 Human)

Use

CRISPR

Available Since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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CRISPRi sgNF1-1

Plasmid

#253096

Purpose

CRISPRi single-guide against NF1

Depositor

Harish Vasudevan

Article

Vasudevan et al Proc Natl Acad Sci U S A. 2025 Jul 8;122

Insert

NF1 (NF1 Human)

Use

CRISPR

Available Since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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CRISPRi sgSOS1-1

Plasmid

#253092

Purpose

CRISPRi single-guide against SOS1

Depositor

Harish Vasudevan

Article

Vasudevan et al Proc Natl Acad Sci U S A. 2025 Jul 8;122

Insert

SOS1 (SOS1 Human)

Use

CRISPR

Available Since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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CRISPRi sgPTPN11-1

Plasmid

#253090

Purpose

CRISPRi single-guide against PTPN11

Depositor

Harish Vasudevan

Article

Vasudevan et al Proc Natl Acad Sci U S A. 2025 Jul 8;122

Insert

PTPN11 (PTPN11 Human)

Use

CRISPR

Available Since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG-human SLC9C1-3xFlag

Plasmid

#249411

Purpose

Expression vector of human SLC9C1 tagged with 3xFLAG at C-terminus under the CAG promoter.

Depositor

Masahito Ikawa

Article

Iida-Norita et al Proc Natl Acad Sci U S A. 2025 Oct 21;12

Insert

SLC9C1 (SLC9C1 Human)

Tags

3xFLAG

Expression

Mammalian

Promoter

CAG

Available Since

Feb. 25, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG-mouse Tmem217-3xFlag

Plasmid

#249409

Purpose

Expression vector of mouse Tmem217 tagged with 3xFLAG at C-terminus under the CAG promoter.

Depositor

Masahito Ikawa

Article

Iida-Norita et al Proc Natl Acad Sci U S A. 2025 Oct 21;12

Insert

Transmembrane protein 217 (Tmem217 Mouse)

Expression

Mammalian

Available Since

Feb. 25, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG-mouse Slc9c1-PA

Plasmid

#249412

Purpose

Expression vector of mouse SLC9C1 tagged with PA at C-terminus under the CAG promoter

Depositor

Masahito Ikawa

Article

Iida-Norita et al Proc Natl Acad Sci U S A. 2025 Oct 21;12

Insert

Slc9c1 (Slc9c1 Mouse)

Tags

PA

Expression

Mammalian

Promoter

CAG

Available Since

Feb. 22, 2026

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(K55R)-Avi

Plasmid

#245186

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

K55R

Available Since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(T52S)-Avi

Plasmid

#245185

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

T52S

Available Since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(L43F)-Avi

Plasmid

#245184

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

L43F

Available Since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(T42A)-Avi

Plasmid

#245183

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

T42A

Available Since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(WT)-Avi

Plasmid

#245182

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

wild-type

Available Since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-C-SH2(R138Q)-Avi

Plasmid

#245189

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 C-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

R138Q

Available Since

Oct. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-N-SH2(E76K)-Avi

Plasmid

#245187

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 N-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

E76K

Available Since

Oct. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-C-SH2(WT)-Avi

Plasmid

#245188

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 C-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

wild-type

Available Since

Oct. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pET-SUMO-SHP2-C-SH2(E139D)-Avi

Plasmid

#245190

Purpose

Production of N-terminally His-SUMO-tagged and C-terminally Avi-tagged SH2 domain

Depositor

Neel Shah

Article

van Vlimmeren et al Proc Natl Acad Sci U S A. 2024 Jul 23;12

Insert

SHP2 C-SH2

Tags

Avi and His-SUMO

Expression

Bacterial

Mutation

E139D

Available Since

Sept. 29, 2025

Availability

Academic Institutions and Nonprofits only

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pDB2-hCRY2-mClover3-CD4-bla

Plasmid

#189983

Purpose

Donor Vector to integrate mClover3 C-terminal into the human CRY2 Locus to express it as a fusion protein

Depositor

Achim Kramer

Article

Gabriel et al Proc Natl Acad Sci U S A. 2024 Aug 20;12

Insert

mClover3

Use

CRISPR

Tags

3xFlag

Available Since

July 24, 2025

Availability

Academic Institutions and Nonprofits only

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pDB2-hPER1-mClover3-CD4-bla

Plasmid

#189979

Purpose

Donor Vector to integrate mClover3 C-terminal into the human PER1 Locus to express it as a fusion protein

Depositor

Achim Kramer

Article

Gabriel et al Proc Natl Acad Sci U S A. 2024 Aug 20;12

Insert

mClover3

Use

CRISPR

Tags

3xFlag

Available Since

July 24, 2025

Availability

Academic Institutions and Nonprofits only

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pAPH07

Plasmid

#234345

Purpose

Library-scale IPTG-inducible gRNA expression for Type II dCas9 in Synechococcus sp. PCC 7002, genomically integrated next to glpK

Depositor

Jerome Fox

Article

Hren et al Proc Natl Acad Sci U S A. 2025 Mar 25;12

Insert

Type II dCas9 sgRNA

Use

CRISPR

Expression

Bacterial

Promoter

lacUV5

Available Since

April 24, 2025

Availability

Academic Institutions and Nonprofits only

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