Purpose
              
              Expresses TRE3GV promoter driven human codon optimized SpdCas9 directly fused to Dnmt3A/3L variant catΔ (C706A and R832E) and hPGK promoter driven mCherry
             
          
          
          
            
          
        
          
  
  
    
      
        Inserts
      
      
        
          S. pyogenes dCas9 with C-terminal fusion of murine Dnmt3A-Dnmt3L variant catΔ (C706A and R832E) engineered fusion
        
          mCherry
        
      
    
   
  
  
    
  
  
    
  
  
    
  
  
    
      
        Mutation
      
      D10A and H840A in S.pyogenes Cas9; C706A and R832…
     
  
  
    
  
         
          
            
              
                Available Since
              
              
                Feb. 7, 2025
              
             
          
          
            
              Availability
            
            
              
                Academic Institutions and Nonprofits only