We narrowed to 1,391 results for: lentiviral backbone

1. MTK Lentivirus Single Cassette Destination Vector (pAN2414)

   Plasmid

   #194220

   Purpose

   Backbone for constructing single casette expression plasmids using the Mammalian Tookit

   Depositor

   Hana El-Samad

   Article

   Weinberg et al bioRxiv 2021.04.20.440678

   Type

   Empty backbone

   Use

   Lentiviral

   Available Since

   Sept. 10, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. TDP-REGv2(mScarlet-FLAG)#7 in pTwist-CMV backbone

   Plasmid

   #216152

   Purpose

   Expresses mScarlet in cells with TDP-43 loss-of-function. This plasmid has one of the best dynamic ranges of those tested (~100-fold) in SK-N-BE2 cells. It uses a cryptic exon. [Code 'A11'] Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments

   Depositor

   Pietro Fratta

   Article

   Wilkins et al Science. 2024 Oct 4;386(6717):61-69. doi

   Insert

   mScarlet with cryptic exon and C-terminal FLAG
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. TDP-REGv2(mScarlet-FLAG)#9 in pTwist-CMV backbone

   Plasmid

   #216153

   Purpose

   Expresses mScarlet in cells with TDP-43 loss-of-function. Has one of the best dynamic ranges of those tested (~100-fold) in SK-N-BE2 cells (brighter than #7). It uses a single intron. [Code 'B11']. Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments

   Depositor

   Pietro Fratta

   Article

   Wilkins et al Science. 2024 Oct 4;386(6717):61-69. doi

   Insert

   mScarlet with cryptic splice site and C-terminal FLAG tag
   

   Expression

   Mammalian

   Available Since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. TDP-REGv2(mScarlet-FLAG)#10 in pTwist-CMV backbone

   Plasmid

   #216154

   Purpose

   Expresses mScarlet in cells with TDP-43 loss-of-function. Leaky but very sensitive to mild TDP-43 loss of function. It uses a cryptic exon. [Code 'B5'] Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments

   Depositor

   Pietro Fratta

   Article

   Wilkins et al Science. 2024 Oct 4;386(6717):61-69. doi

   Insert

   mScarlet with cryptic exon and C-terminal FLAG
   

   Expression

   Mammalian

   Available Since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. TDP-REGv2(mScarlet-FLAG)#11 in pTwist-CMV backbone

   Plasmid

   #216155

   Purpose

   Expresses mScarlet in cells with TDP-43 loss-of-function. Very bright and decent dynamic range (>10-fold), slightly leaky. It uses a single intron. [Code 'B12']. Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor Comments

   Depositor

   Pietro Fratta

   Article

   Wilkins et al Science. 2024 Oct 4;386(6717):61-69. doi

   Insert

   mScarlet with cryptic splice site and C-terminal FLAG tag
   

   Expression

   Mammalian

   Available Since

   July 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A

   Pooled Library

   #92385

   Purpose

   Crispri

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Has Service

   Lentiviral Prep

   Use

   Lentiviral

   Available Since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

7. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92379

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Has Service

   Lentiviral Prep

   Use

   Lentiviral

   Available Since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

8. Human sgRNA library Gattinara in pRDA_118 backbone

   Pooled Library

   #136986

   Purpose

   Expresses sgRNAs targeting human genes

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

9. Mouse sgRNA library Gouda in pRDA_118 backbone

   Pooled Library

   #136987

   Purpose

   Expresses sgRNAs targeting mouse genes

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set B

    Pooled Library

    #92386

    Purpose

    Crispri

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

11. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

    Pooled Library

    #104090

    Purpose

    Crispri

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

12. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set B

    Pooled Library

    #104091

    Purpose

    Crispri

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

13. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92380

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Use

    Lentiviral

    Available Since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only

14. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75314

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

15. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

    Pooled Library

    #75315

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

16. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set A

    Pooled Library

    #92383

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

17. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92384

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

18. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

    Pooled Library

    #75312

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

19. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

    Pooled Library

    #75313

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

20. pAG Lenti CMV Empty Puro

    Plasmid

    #236083

    Purpose

    Empty lentiviral backbone

    Depositor

    Melina Fan

    Type

    Empty backbone

    Use

    Lentiviral

    Promoter

    CMV

    Available Since

    April 25, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

21. pAG Lenti CMV N-HA Puro

    Plasmid

    #236079

    Purpose

    Empty lentiviral backbone with N-terminal HA tag

    Depositor

    Melina Fan

    Type

    Empty backbone

    Use

    Lentiviral

    Tags

    HA

    Promoter

    CMV

    Available Since

    April 25, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

22. pAG Lenti CMV C-HA Puro

    Plasmid

    #236080

    Purpose

    Empty lentiviral backbone with C-terminal HA tag

    Depositor

    Melina Fan

    Type

    Empty backbone

    Use

    Lentiviral

    Tags

    HA

    Promoter

    CMV

    Available Since

    April 25, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

23. pAG Lenti CMV EGFP Puro

    Plasmid

    #236084

    Purpose

    Lentiviral backbone expressing EGFP, control for empty backbone 236083

    Depositor

    Melina Fan

    Insert

    EGFP
    

    Use

    Lentiviral

    Promoter

    CMV

    Available Since

    April 25, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

24. pAG Lenti CMV HA-EGFP Puro

    Plasmid

    #236081

    Purpose

    Lentiviral backbone expressing N-terminally HA tagged EGFP, control for empty backbone 236079

    Depositor

    Melina Fan

    Insert

    EGFP
    

    Use

    Lentiviral

    Tags

    HA

    Promoter

    CMV

    Available Since

    April 25, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

25. pAG Lenti CMV EGFP-HA Puro

    Plasmid

    #236082

    Purpose

    Lentiviral backbone expressing C-terminally HA tagged EGFP, control for empty backbone 236080

    Depositor

    Melina Fan

    Insert

    EGFP
    

    Use

    Lentiviral

    Tags

    HA

    Promoter

    CMV

    Available Since

    April 25, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

26. pGMC00017 (aka pRC0162)

    Plasmid

    #195319

    Purpose

    Lentiviral guide RNA backbone derived from pSB700 with puromycin

    Depositor

    Raj Chari

    Type

    Empty backbone

    Use

    CRISPR, Lentiviral, and Synthetic Biology

    Expression

    Mammalian

    Available Since

    March 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pGMC00026 (aka pRC0462)

    Plasmid

    #195318

    Purpose

    Lentiviral guide RNA backbone derived from pSB700 with neomycin/G418

    Depositor

    Raj Chari

    Type

    Empty backbone

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    March 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pGMC00022 (aka pRC0433)

    Plasmid

    #195321

    Purpose

    Lentiviral expression vector derived from LEGO-G2 with hygromycin selection

    Depositor

    Raj Chari

    Type

    Empty backbone

    Use

    Lentiviral and Synthetic Biology

    Expression

    Mammalian

    Available Since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pGMC00020 (aka pRC0431)

    Plasmid

    #195304

    Purpose

    Lentiviral expression vector derived from LEGO-G2 with blasticidin selection

    Depositor

    Raj Chari

    Type

    Empty backbone

    Use

    Lentiviral and Synthetic Biology

    Expression

    Mammalian

    Available Since

    Feb. 23, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pGMC00021 (aka pRC0432)

    Plasmid

    #195305

    Purpose

    Lentiviral expression vector derived from LEGO-G2 with puromycin selection

    Depositor

    Raj Chari

    Type

    Empty backbone

    Use

    Lentiviral and Synthetic Biology

    Expression

    Mammalian

    Available Since

    Feb. 23, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge