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  3. pGL2 HNF4A P2 mut

    Plasmid
    #60325
    Purpose
    Mutated HNF4A P2 promoter region cloned into the pGL2-basic backbone. The -181 G to A mutation is in a HNF1alpha binding site and cosegregates with MODY.
    Depositor
    Jorge Ferrer
    Article
    Hansen et al J Clin Invest. 2002 Sep;110(6):827-33.
    Insert
    HNF4A P2 mut (-181 G to A) (HNF4A Human)
    Use
    Luciferase
    Tags
    Luciferase
    Expression
    Mammalian
    Mutation
    The -181 G to A mutation is in a HNF1alpha bindin…
    Available Since
    Jan. 6, 2015
    Availability
    Academic Institutions and Nonprofits only

  6. pZE21/UBP1/ClpS_V65I

    Plasmid
    #98567
    Purpose
    Expresses truncated codon-opt S. cerevisiae UBP1 and the V65I engineered variant of E. coli ClpS in an artificial operon
    Depositor
    George Church
    Article
    Kunjapur et al Proc Natl Acad Sci U S A. 2018 Jan 16;11
    Inserts
    Truncated ubiquitin cleavase, codon optimized
    Mutated ATP-dependent Clp protease adapter protein
    Expression
    Bacterial
    Mutation
    Contains the V65I mutation that increases discrim…
    Available Since
    Feb. 7, 2018
    Availability
    Academic Institutions and Nonprofits only
    98567-plasmid-map-sequence-id-203054

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