We narrowed to 39,142 results for: kan

1. pCMV5-Flag-Ago2-FDM2

   Plasmid

   #72209

   Purpose

   Mammalian expression of aa 1-517 of human Ago2

   Depositor

   Mien-Chie Hung

   Article

   Shen et al Nature. 2013 May 16;497(7449):383-7. doi

   Insert

   argonaute RISC catalytic component 2 (AGO2 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Δ 518-860

   Promoter

   CMV

   Available since

   May 4, 2016

   Availability

   Academic Institutions and Nonprofits only

2. pCMV5-Flag-Ago2-FDM4

   Plasmid

   #72211

   Purpose

   Mammalian expression of aa 373-860 of human Ago2

   Depositor

   Mien-Chie Hung

   Article

   Shen et al Nature. 2013 May 16;497(7449):383-7. doi

   Insert

   argonaute RISC catalytic component 2 (AGO2 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Δ 1-372

   Promoter

   CMV

   Available since

   May 4, 2016

   Availability

   Academic Institutions and Nonprofits only

3. pCMV5-Flag-Ago2-FDM5

   Plasmid

   #72212

   Purpose

   Mammalian expression of aa 518-860 of human Ago2

   Depositor

   Mien-Chie Hung

   Article

   Shen et al Nature. 2013 May 16;497(7449):383-7. doi

   Insert

   argonaute RISC catalytic component 2 (AGO2 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Δ 1-517

   Promoter

   CMV

   Available since

   May 4, 2016

   Availability

   Academic Institutions and Nonprofits only

4. pXPR_BRD003 LIAS-1

   Plasmid

   #184478

   Purpose

   Lentivirus gRNA targeting human LIAS gene

   Depositor

   Peter Tsvetkov, Todd Golub

   Article

   Tsvetkov et al Science. 2022 Mar 18;375(6586):1254-1261

   Insert

   LIAS (LIAS Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   June 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pXPR_BRD003 LIAS-2

   Plasmid

   #184479

   Purpose

   Lentivirus gRNA targeting human LIAS gene

   Depositor

   Peter Tsvetkov, Todd Golub

   Article

   Tsvetkov et al Science. 2022 Mar 18;375(6586):1254-1261

   Insert

   LIAS (LIAS Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   June 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pLKO-Tet-On-PLXNB2-shRNA2

   Plasmid

   #98400

   Purpose

   Lentivirus for expression of shRNA2 against human PLEXIN-B2 (Dox-inducible)

   Depositor

   Roland Friedel

   Article

   Junqueira Alves et al Nat Commun. 2021 Oct 14;12(1):6019. doi:

   Insert

   Plexin-B2 (PLXNB2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   July 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. DHFR-C-HiBiT

   Plasmid

   #207119

   Purpose

   Bacterially expressed DHFR-HiBiT for Ni-NTA purification

   Depositor

   James Inglese

   Article

   Ciulla et al Nat Commun. 2025 May 10;16(1):4342. doi:

   Insert

   Human-dihydrofolate reductase-HiBiT-10xHis (DHFR Human)
   

   Use

   Tags

   10xHis-tag and HiBiT tag

   Expression

   Bacterial

   Mutation

   Codon optmization for expression in BL21DE3

   Promoter

   T7

   Available since

   May 13, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pX458_mCherry-HP1a-gRNA-2

   Plasmid

   #237635

   Purpose

   Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

   Depositor

   Denes Hnisz

   Article

   Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

   Insert

   HP1a gRNA (CBX5 Human)
   

   Use

   CRISPR

   Tags

   mCherry

   Expression

   Mutation

   Promoter

   Available since

   May 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pRK5_mEGFP-SS18-SSX1-KS

   Plasmid

   #237679

   Purpose

   For overexpression of mEGFP-SS18-SSX1-KS

   Depositor

   Denes Hnisz

   Article

   Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

   Insert

   SS18-SSX1-KS (SS18, SSX1 Human)
   

   Use

   Tags

   mEGFP

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   May 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pRK5_mEGFP-SS18-SSX1

    Plasmid

    #237678

    Purpose

    For overexpression of mEGFP-SS18-SSX1

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX1 (SS18, SSX1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pRK5_mEGFP-SS18-SSX2-KS

    Plasmid

    #237680

    Purpose

    For overexpression of mEGFP-SS18-SSX2-KS

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    SS18-SSX2-KS (SS18, SSX2 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pX458_mCherry-HP1a-gRNA-1

    Plasmid

    #237634

    Purpose

    Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to HP1a locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    HP1a gRNA (CBX5 Human)
    

    Use

    CRISPR

    Tags

    mCherry

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pX458_mCherry-TCOF1-gRNA

    Plasmid

    #237633

    Purpose

    Cas9 from S. pyogenes with 2A-mCherry, gRNA to knock-in msfGFP to TCOF1 locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    TCOF1 gRNA (TCOF1 Human)
    

    Use

    CRISPR

    Tags

    mCherry

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pUC19_msfGFP-FUS-repair-tempate

    Plasmid

    #237684

    Purpose

    For knock-in msfGFP to FUS locus

    Depositor

    Denes Hnisz

    Article

    Zhang et al Nature. 2025 Jun 4. doi: 10.1038/s41586-

    Insert

    FUS (FUS Human)
    

    Use

    CRISPR

    Tags

    msfGFP

    Expression

    Mutation

    Promoter

    Available since

    May 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pOET3-6xHis-hSMSr-ΔSAMD

    Plasmid

    #236225

    Purpose

    Express N-terminal His-tagged human SMSr (SAMD8)-sterile alpha motif domain deletion mutant protein in insect cells

    Depositor

    Chiaki Murakami

    Article

    Murakami et al J Biol Chem. 2021 Jan-Jun;296:100454. do

    Insert

    SAMD8 (SAMD8 Human)
    

    Use

    Tags

    Hexa histidine tag (6xHis-tag) and enterokinase s…

    Expression

    Insect

    Mutation

    sterile alpha motif domain at N-terminal (1-231 b…

    Promoter

    Available since

    May 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pET21a HsDHFR-bio-10His

    Plasmid

    #193883

    Purpose

    Expresses human dihydrofolate reductase (DHFR) with C-terminal AviTag (Bio) and His10 sequence

    Depositor

    James Inglese

    Article

    Rana et al Cell Chem Biol. 2024 Feb 15;31(2):221-23

    Insert

    human dihydrofolate reductase (DHFR) (DHFR Human)
    

    Use

    Tags

    His tag and biotinylation sequence

    Expression

    Bacterial

    Mutation

    Codon optimized

    Promoter

    T7

    Available since

    Oct. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pSDC803_IKZF1_mutant

    Plasmid

    #224113

    Purpose

    Insect cell expression vector for IKZF1 mutant for CRBN cryoEM pre-blotting

    Depositor

    Eric Fischer

    Article

    Mercer et al Science. 2024 Mar 15;383(6688):eadk4422.

    Insert

    IKZF1 (IKZF1 Human)
    

    Use

    Tags

    Flag-TEV

    Expression

    Insect

    Mutation

    Residues 140-196, Q146A and G151N

    Promoter

    polyhedrin

    Available since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLVX-TetOne-Puro-BCL9

    Plasmid

    #202662

    Purpose

    Tet-ON 3rd generation expression vector with inducible expression of BCL9 and a puromycin selection cassette

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    BCL9 transcription coactivator (BCL9 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pAAV-CMV-FLEX-SaCas9-U6-sgFAAH

    Plasmid

    #209197

    Purpose

    Mutagenesis of Faah

    Depositor

    Larry Zweifel

    Article

    Balsevich et al Elife. 2023 Apr 11;12:e81919. doi: 10.75

    Insert

    Faah (Faah Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Tags

    Expression

    Mutation

    Promoter

    CMV

    Available since

    Jan. 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. MDM4_Deletion_Downstream_gRNA_2

    Plasmid

    #195137

    Purpose

    gRNA in a third generation gRNA backbone with mCherry, targeting region immediately downstream of MDM4, to be used with MDM4_Deletion_Upstream_gRNA_1/2 for MDM4 deletion

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    MDM4 Deletion Downstream gRNA 2 (MDM4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Feb. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge