We narrowed to 87,717 results for: MAL

1. pCHA_SBV_NSs

   Plasmid

   #208938

   Purpose

   Expresses C-terminally HA-tagged Schmallenberg orthobunyavirus NSs protein from CMV promoter in mammalian cells

   Depositor

   Gerald Barry

   Insert

   NSs
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   Deleted 47 bp at 5' end and 510 bp from 3&#x…

   Promoter

   CMV

   Available since

   Jan. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pET28a MDHP_YEAST

   Plasmid

   #204233

   Purpose

   Bacterial expression of yeast peroxisomal malate dehydrogenase ; Use in CURES (integration of research into undergraduate teaching labs).

   Depositor

   Malate dehydrogenase CUREs Community (MCC)

   Insert

   MDHP_YEAST (MDH3 Budding Yeast)
   

   Use

   Tags

   6X His

   Expression

   Bacterial

   Mutation

   The last 3 C-terminal residues (SKL) are the pero…

   Promoter

   Lac

   Available since

   Nov. 6, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. Mouse Chromatin Regulator Library

   Pooled Library

   #200011

   Purpose

   CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

   Depositor

   Bradley Bernstein, Gabriel Griffin, Robert Manguso

   Article

   Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

4. Human Base Editing Sensor Library

   Pooled Library

   #179218

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

5. pLCKO2::TKOv3

   Pooled Library

   #125517

   Purpose

   Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

   Depositor

   Jason Moffat

   Article

   Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 1, 2019

   Availability

   Academic Institutions and Nonprofits only

6. Liu Lab MusCK Library A

   Pooled Library

   #174196

   Purpose

   MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

   Depositor

   Xiaole Shirley Liu

   Article

   Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

7. Mouse Base Editing Sensor Library

   Pooled Library

   #179217

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

8. pCVSN2c-MCP-oScarlet-KASH-6xMS2 Barcode Library

   Pooled Library

   #227672

   Purpose

   RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

   Depositor

   Tomasz Nowakowski, Cathryn Cadwell

   Article

   Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

   Expression

   Mammalian

   Species

   Synthetic

   Available since

   Feb. 12, 2025

   Availability

   Academic Institutions and Nonprofits only

9. Liu Lab MusCK Library B

   Pooled Library

   #174197

   Purpose

   MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

   Depositor

   Xiaole Shirley Liu

   Article

   Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

10. CHyMErA Large-Scale Exon Deletion hgRNA Library

    Pooled Library

    #209736

    Purpose

    CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

11. HR700_TP53Exon5mut

    Pooled Library

    #229137

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

12. HR700_TP53Exon6mut

    Pooled Library

    #229138

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

13. HR700_TP53Exon7mut

    Pooled Library

    #229139

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

14. HR700_TP53Exon8mut

    Pooled Library

    #229140

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

15. ALL-PAM sensor Library

    Pooled Library

    #179219

    Purpose

    10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

16. pAC-Cyc

    Plasmid

    #33156

    Depositor

    Michael Rosbash

    Article

    Kadener et al PLoS Biol. 2008 May 20;6(5):e119.

    Insert

    Cyc (cyc Fly)
    

    Use

    Retroviral

    Tags

    6xHIS and V5

    Expression

    Insect

    Mutation

    Promoter

    Actin 5C

    Available since

    Dec. 8, 2011

    Availability

    Academic Institutions and Nonprofits only

17. pAcUW21-hovimeh1

    Plasmid

    #84211

    Purpose

    baculovirus transfer vector containing hovimeh1 coding sequence from Homalodisca vitripennis

    Depositor

    Bruce Hammock

    Article

    Kamita et al Arch Insect Biochem Physiol. 2013 Aug;83

    Insert

    meh1
    

    Use

    Tags

    Expression

    Insect

    Mutation

    Promoter

    p10

    Available since

    Nov. 8, 2016

    Availability

    Academic Institutions and Nonprofits only

18. KHBD00456

    Plasmid

    #39569

    Depositor

    Bart Deplancke

    Article

    Korneel et al Nat Methods. 2011 Oct 30;8(12):1065-70.

    Insert

    CG8727 (cyc Fly)
    

    Use

    Gateway donr vector

    Tags

    Expression

    Mutation

    Promoter

    none

    Available since

    Aug. 16, 2012

    Availability

    Academic Institutions and Nonprofits only

19. pCMS-eGFP-RTP801

    Plasmid

    #65057

    Purpose

    Expression of RTP801 in mammalian cells

    Depositor

    Cristina Malagelada, Lloyd Greene

    Article

    Malagelada et al J Neurosci. 2006 Sep 27;26(39):9996-1000

    Insert

    DDIT4 (Ddit4 Rat)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV-IE

    Available since

    May 19, 2015

    Availability

    Academic Institutions and Nonprofits only

20. EF1α-mNeonGreen-Z1

    Plasmid

    #135613

    Purpose

    mNeonGreen monomeric fluorescent protein expression for mammalian cells under EF1a-HTLV promoter in minimal backbone plasmid.

    Depositor

    Jordan Green

    Insert

    mNeonGreen
    

    Use

    Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a-HTLV

    Available since

    May 28, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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