We narrowed to 895 results for: gcat

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pSuper DGK zeta human

Plasmid

#224575

Purpose

To downregulate the expression of human DGK zeta in human cells

Depositor

Isabel Mérida

Article

Avila-Flores et al Immunol Cell Biol. 2017 Jul;95(6):549-56

Insert

sh RNAi Diacylglycerol kinase zeta human (DGKZ Human)

Use

RNAi

Promoter

H1

Available Since

Sept. 19, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(ARID2(14))-PGKpuro2ABFP-W

Plasmid

#200472

Purpose

Lentiviral vector expressing gRNA targeting human ARID2

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

ARID2(14) (ARID2 Human)

Use

Lentiviral

Available Since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

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pSpCas9(BB)-2A-GFP_MAPRE1-KI-gRNA#1

Plasmid

#197424

Purpose

π-element knock-in into exon 5 of MAPRE1

Depositor

Torsten Wittmann

Article

Dema et al Elife. 2023 Jan 30;12:e84143. doi: 10.75

Insert

MAPRE1 gRNA #1 (targets Exon 5) for π-element knock-in (MAPRE1 Human)

Expression

Mammalian

Available Since

June 26, 2023

Availability

Academic Institutions and Nonprofits only

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pSpCas9(BB)-2A-GFP_MAPRE1-KI-gRNA#2

Plasmid

#197425

Purpose

π-element knock-in into exon 5 of MAPRE1

Depositor

Torsten Wittmann

Article

Dema et al Elife. 2023 Jan 30;12:e84143. doi: 10.75

Insert

MAPRE1 gRNA #2 (targets Exon 5) for π-element knock-in (MAPRE1 Human)

Expression

Mammalian

Available Since

June 26, 2023

Availability

Academic Institutions and Nonprofits only

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pDF0428 huDisCas7-11-R1045-GGGS-R1122-U6-pro-Gluc

Plasmid

#186985

Purpose

AAV transgene plasmid for Cas7-11-R1045-GGGS-R1122, with U6 promoter-driven expression of Gluc crRNA guide

Depositor

Omar Abudayyeh, Jonathan Gootenberg

Article

Kato et al Cell. 2022 May 25. pii: S0092-8674(22)00

Insert

cas7-11-r1045-gggs-r1122, Gluc crRNA guide

Use

AAV

Mutation

r1045-gggs-r1122 deletion

Available Since

Sept. 6, 2022

Availability

Academic Institutions and Nonprofits only

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lentiSAMv2 rs11257655-guide3

Plasmid

#118206

Purpose

CRISPR-mediated activation of human islet enhancer containing T2D-associated variant rs11257655 (CDC123/CAMK1D GWAS locus)

Depositor

Jorge Ferrer

Article

Miguel-Escalada et al Nat Genet. 2019 Jun 28. pii: 10.1038/s41

Insert

dCas9-VP64-2A-BlastR

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

EF1a core and U6

Available Since

April 2, 2019

Availability

Academic Institutions and Nonprofits only

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pSico shMAP3K2 human

Plasmid

#85656

Purpose

expression of shRNA targeting human MAP3K2

Depositor

Julien Sage

Article

Mazur et al Nature. 2014 Jun 12;510(7504):283-7. doi

Insert

shRNA targeting 3'UTR of MAP3K2 (MAP3K2 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Promoter

U6

Available Since

Jan. 27, 2017

Availability

Academic Institutions and Nonprofits only

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AK7 gRNA (BRDN0001145278)

Plasmid

#77913

Purpose

3rd generation lentiviral gRNA plasmid targeting human AK7

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

AK7 (AK7 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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COL4A3BP gRNA (BRDN0001147254)

Plasmid

#77850

Purpose

3rd generation lentiviral gRNA plasmid targeting human COL4A3BP

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

COL4A3BP

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CLK2 gRNA (BRDN0001147894)

Plasmid

#77605

Purpose

3rd generation lentiviral gRNA plasmid targeting human CLK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CLK2 (CLK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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HIPK4 gRNA (BRDN0001147818)

Plasmid

#77475

Purpose

3rd generation lentiviral gRNA plasmid targeting human HIPK4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

HIPK4 (HIPK4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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N4BP2 gRNA (BRDN0001146056)

Plasmid

#76338

Purpose

3rd generation lentiviral gRNA plasmid targeting human N4BP2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

N4BP2 (N4BP2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ADK gRNA (BRDN0001147557)

Plasmid

#75745

Purpose

3rd generation lentiviral gRNA plasmid targeting human ADK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ADK (ADK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ADRBK1 gRNA (BRDN0001145957)

Plasmid

#75682

Purpose

3rd generation lentiviral gRNA plasmid targeting human ADRBK1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ADRBK1

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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NEK11 gRNA (BRDN0001146419)

Plasmid

#75562

Purpose

3rd generation lentiviral gRNA plasmid targeting human NEK11

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

NEK11 (NEK11 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pAAV_3x_U6_mmp25_CAG_nlsTagBFP2

Plasmid

#247935

Purpose

Targeting mmp25 gene in vivo by adeno-associated viral vector-mediated delivery

Depositor

Benoit Vanhollebeke

Article

Panji et al Commun Biol. 2026 Feb 25;9(1):479. doi:

Insert

mmp25 sgRNAs (Mmp25 Mouse)

Use

AAV, CRISPR, and Mouse Targeting

Tags

nls-TagBFP2

Expression

Mammalian

Promoter

U6

Available Since

June 1, 2026

Availability

Academic Institutions and Nonprofits only

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pLV hU6-sgNT2-2-hUbC-dCas9-KRAB-T2a-Puro

Plasmid

#255340

Purpose

CRISPRi nontargeting control

Depositor

Kenneth Chen

Article

Tiburcio et al Mol Cancer Res. 2024 Aug 2;22(8):711-720

Insert

sgNT2

Use

CRISPR and Lentiviral

Available Since

May 7, 2026

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(sgCXCR2-2)-PGKpuro2ABFP-W

Plasmid

#252918

Purpose

Expression vector for gRNA with Puro and tagBFP selection markers

Depositor

Sok Ching Cheong

Insert

CXCR2 (CXCR2 Human)

Use

CRISPR

Promoter

human U6 promoter, mouse PGK promoter

Available Since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR V2 Hygro sgDDX58

Plasmid

#241451

Purpose

Delete DDX58 (RIG-I)

Depositor

Richard Possemato

Insert

sgDDX58 (RIGI Synthetic)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 2, 2026

Availability

Academic Institutions and Nonprofits only

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pTol1-U6abc_amhc(myh6)_cmlc2-nmKate

Plasmid

#238375

Purpose

Drives expression of 3 different gRNAs targeting amhc (myh6), and expression of nclear mKate in cardiomyocytes.

Depositor

Juan Manuel González-Rosa

Article

Keeley et al Cell Rep Methods. 2025 Mar 24;5(3):10100

Insert

nuclear mKate/3 gRNAs targeting amhc

Promoter

cmlc2 (nmKate); U6 (gRNAs)

Available Since

Nov. 17, 2025

Availability

Academic Institutions and Nonprofits only

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