We narrowed to 353 results for: TP53

1. PB-TRE3G-dN40-TP53-CCRB

   Plasmid

   #236774

   Purpose

   A piggybac-based cloning vector containing TRE3G promoter-driven short-form of TP53 and CAG promoter-driven nuclear-localized Clover-P2A-rtTA-IRES-BSD.

   Depositor

   Kazutoshi Takahashi

   Article

   Okubo et al Sci Adv. 2025 Apr 11;11(15):eadq5484. do

   Insert

   TP53 (TP53 Human)
   

   Use

   Piggybac

   Tags

   Expression

   Mammalian

   Mutation

   deleted amino acids 1-40

   Promoter

   TRE3G promoter and TRE3G promoter, CAG promoter

   Available since

   May 29, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. Control-TP53-LRG-GFP

   Plasmid

   #225874

   Purpose

   Guides targeting P53 and a control sequence

   Depositor

   Janai Carr-Ascher

   Article

   Freeland et al Clin Cancer Res. 2024 Aug 23. doi: 10.11

   Insert

   Control and TP53 (TP53 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Oct. 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. RB1-TP53-LRG-GFP

   Plasmid

   #225876

   Purpose

   Guides targeting TP53 and RB1

   Depositor

   Janai Carr-Ascher

   Article

   Freeland et al Clin Cancer Res. 2024 Aug 23. doi: 10.11

   Insert

   RB1 and TP53 (TP53, RB1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   Oct. 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pUC-T7-hTP53-P0~670-FLuc

   Plasmid

   #208640

   Purpose

   for in vitro transcription template preparation, insert T7 promoter, TP53 translation initiation site P0 to +670 and F-luc from pGL3-Basic, into pUC19. P0~670 is confusing, BLAST is recommended.

   Depositor

   Quanfu Ma

   Insert

   TP53, UTR and partial CDS (TP53 Human)
   

   Use

   Luciferase; In vitor transcription template

   Tags

   Firefly Luciferase (F-Luc) and T7 promoter

   Expression

   Mutation

   UTR and partial CDS in-frame with F-Luc

   Promoter

   T7

   Available since

   Jan. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pAav-TP53-PQS1-3xFLAG

   Plasmid

   #84884

   Purpose

   rAAV-based template for genome engineering of the p53 C-terminus containing PQS1 and 3xFLAG tags and a selection cassette

   Depositor

   Sven Eyckerman

   Article

   Vandemoortele et al Sci Rep. 2016 Jun 6;6:27220. doi: 10.103

   Inserts

   TP53 genomic region HR1 (TP53 Human)
   TP53 genomic region HR2
   

   Use

   AAV

   Tags

   PQS1 3xFLAG

   Expression

   Mutation

   Promoter

   no and no

   Available since

   Nov. 28, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. TP53 MITE Library

   Pooled Library

   #113569

   Purpose

   Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

   Depositor

   William Hahn, David Root

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

7. HR700_TP53Exon5mut

   Pooled Library

   #229137

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

8. HR700_TP53Exon6mut

   Pooled Library

   #229138

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

9. HR700_TP53Exon7mut

   Pooled Library

   #229139

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

10. HR700_TP53Exon8mut

    Pooled Library

    #229140

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

11. TAL2472

    Plasmid

    #36853

    Depositor

    Keith Joung

    Article

    Reyon et al Nat Biotechnol. 2012 Apr 8. doi: 10.1038

    Insert

    TP53-TALEN_Right (Tp53 Human)
    

    Use

    Mammalian, t7 for in vitro mrna synthesis

    Tags

    3X Flag and WT FOKI

    Expression

    Mutation

    Promoter

    CMV

    Available since

    June 26, 2012

    Availability

    Academic Institutions and Nonprofits only

12. TAL2348

    Plasmid

    #36768

    Depositor

    Keith Joung

    Article

    Reyon et al Nat Biotechnol. 2012 Apr 8. doi: 10.1038

    Insert

    TP53-TALEN_Left (Tp53 Human)
    

    Use

    Mammalian, t7 for in vitro mrna synthesis

    Tags

    3X Flag and WT FOKI

    Expression

    Mutation

    Promoter

    CMV

    Available since

    June 26, 2012

    Availability

    Academic Institutions and Nonprofits only

13. MiniCoopR U6:gRNA p53, mitfa:Cas9

    Plasmid

    #118841

    Purpose

    Targets tp53 and expresses zebrafish mitfa specifically in zebrafish melanocytes

    Depositor

    Leonard Zon

    Article

    Ablain et al Science. 2018 Nov 1. pii: science.aau650

    Insert

    tp53 gRNA (tp53 Zebrafish)
    

    Use

    CRISPR; Tol2

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 21, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. EF1a-hP53DD (TET)

    Plasmid

    #214083

    Purpose

    Mammalian expression tetramerization domain (TET) of human TP53

    Depositor

    Ting Zhou

    Article

    Wu et al Nat Commun. 2024 Dec 30;15(1):10824. doi

    Insert

    hP53DD (TP53 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    June 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. EF1a-hP53DD (TET+CTD)

    Plasmid

    #214082

    Purpose

    Mammalian expression tetramerization domain (TET) and C-terminal negative regulatory domain (CTD) of human TP53

    Depositor

    Ting Zhou

    Article

    Wu et al Nat Commun. 2024 Dec 30;15(1):10824. doi

    Insert

    hP53DD (TP53 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    June 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pLVUHshp53

    Plasmid

    #11653

    Depositor

    Patrick Aebischer, Didier Trono

    Article

    Szulc et al Nat Methods. 2006 Feb;3(2):109-16. doi:

    Insert

    GFP, shRNA against TP53 (TP53 Human)
    

    Use

    Cre/Lox, Lentiviral, and RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 17, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pGEX-p53 R175H

    Plasmid

    #39480

    Depositor

    Ie-Ming Shih

    Article

    Guan et al Cancer Res. 2011 Nov 1;71(21):6718-27. E

    Insert

    TP53 (TP53 Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    P72R and R175H

    Promoter

    Available since

    Sept. 25, 2012

    Availability

    Academic Institutions and Nonprofits only

18. pGEX-p53

    Plasmid

    #39479

    Depositor

    Ie-Ming Shih

    Article

    Guan et al Cancer Res. 2011 Nov 1;71(21):6718-27. E

    Insert

    TP53 (TP53 Human)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    P72R

    Promoter

    Available since

    Sept. 25, 2012

    Availability

    Academic Institutions and Nonprofits only

19. pET23 P53DBD

    Plasmid

    #174503

    Purpose

    express P53 DNA binding domain (94-312) in E.coli without tag

    Depositor

    Stewart Loh

    Article

    Butler et al Biochemistry. 2003 Mar 4;42(8):2396-403.

    Insert

    P53 DNA binding domain (corresponds to amino acid 94-312) (TP53 Human)
    

    Use

    Tags

    none

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available since

    Oct. 7, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLVUHshp53-tTR-KRAB

    Plasmid

    #11654

    Depositor

    Patrick Aebischer, Didier Trono

    Article

    Szulc et al Nat Methods. 2006 Feb;3(2):109-16. doi:

    Insert

    hUbiquitin C, GFP, tTR-KRAB, shRNA against TP53, no tetO (TP53 Human)
    

    Use

    Cre/Lox, Lentiviral, and RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 17, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge