We narrowed to 1,274 results for: AP2

1. sgMTOR_49

   Plasmid

   #125132

   Purpose

   Targeting 49th exon of human MLST8 gene by CRISPR-Cas9

   Depositor

   Jin Chen

   Article

   Hwang et al Cancer Res. 2019 Jul 1;79(13):3178-3184.

   Insert

   MTOR (MTOR Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   May 24, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. 782 pMEActMEK

   Plasmid

   #31166

   Depositor

   Nathan Lawson

   Article

   Covassin et al Dev Biol. 2009 May 15. 329(2):212-26.

   Insert

   MEK (MAP2K1 Human)
   

   Use

   Entry vector

   Tags

   Expression

   Mutation

   Ser218Glu Ser222Asp; activated MEKK

   Promoter

   Available since

   Aug. 11, 2011

   Availability

   Academic Institutions and Nonprofits only

3. pFETCh_MED13_iso1

   Plasmid

   #135733

   Purpose

   Donor vector for 3' FLAG tag of human MED13_iso1

   Depositor

   Richard M. Myers

   Article

   Savic et al Genome Res. 2015 Sep 9.

   Insert

   MED13_iso1 Homology arms (MED13 Human)
   

   Use

   CRISPR

   Tags

   3XFLAG-P2A-NeoR

   Expression

   Mutation

   Promoter

   Available since

   Feb. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. pEBG-MKK4 (GST)

   Plasmid

   #21563

   Depositor

   Leonard Zon

   Article

   Sanchez et al Nature. . 372(6508):794-8.

   Insert

   mitogen-activated protein kinase kinase 4 (Map2k4 Mouse)
   

   Use

   Tags

   GST

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   July 17, 2009

   Availability

   Academic Institutions and Nonprofits only

5. pQTEV-ILKAP

   Plasmid

   #34817

   Depositor

   Konrad Buessow

   Article

   Bussow et al Microb Cell Fact. 2005 Jul 5. 4():21.

   Insert

   integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP Human)
   

   Use

   Tags

   His and TEV

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   March 22, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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6. pminiT-Halo-MED1 donor

   Plasmid

   #197868

   Purpose

   Donor plasmid used for building Halo-MED1 knock-in mESCs

   Depositor

   James Zhe Liu

   Article

   Dong et al bioRxiv 2022.10.26.513917

   Insert

   CRSP210 (Med1 Mouse)
   

   Use

   Mouse Targeting

   Tags

   Halotag

   Expression

   Mutation

   Promoter

   NA

   Available since

   March 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLKO-shcIAP1-B

   Plasmid

   #44131

   Depositor

   William Hahn

   Article

   Shen et al Mol Cell Biol. 2012 Dec;32(23):4756-68.

   Insert

   c-IAP1 (BIRC2 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   April 10, 2013

   Availability

   Academic Institutions and Nonprofits only

8. pCMV-Flag-YAP-S61A

   Plasmid

   #33087

   Depositor

   Kunliang Guan

   Article

   Zhao et al Genes Dev. 2007 Nov 1. 21(21):2747-61.

   Insert

   YAP (YAP1 )
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   S61A

   Promoter

   CMV

   Available since

   March 21, 2012

   Availability

   Academic Institutions and Nonprofits only

9. PX330_MED13_iso1_1

   Plasmid

   #135751

   Purpose

   Encodes gRNA for 3' target of human MED13_iso1

   Depositor

   Richard M. Myers

   Article

   Savic et al Genome Res. 2015 Sep 9.

   Insert

   MED13_iso1 gRNA (MED13 Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   Jan. 28, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pcDNA3.1 FLAG mTOR 1968-2549 S2035T

    Plasmid

    #23000

    Depositor

    Jing Huang

    Article

    Lomenick et al Proc Natl Acad Sci U S A. 2009 Dec 7. ()

    Insert

    mTOR (MTOR Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    S2035T aa 1968-2549 only

    Promoter

    Available since

    May 18, 2010

    Availability

    Academic Institutions and Nonprofits only

11. pGEX-2T-FRB-W2027F

    Plasmid

    #73341

    Purpose

    Point mutation Trp 2027 → Phe in the FKBP12-rapamycin binding (FRB) domain of mTOR

    Depositor

    Jie Chen

    Article

    Vilella-Bach et al J Biol Chem. 1999 Feb 12. 274(7):4266-72

    Insert

    FKBP12-rapamycin binding (FRB) domain of MTOR (MTOR Human)
    

    Use

    Tags

    GST-tagged

    Expression

    Bacterial

    Mutation

    FRB domain only aa2015-2114; W2027F

    Promoter

    Available since

    April 19, 2016

    Availability

    Academic Institutions and Nonprofits only

12. pCMV-Flag-YAP-S381A

    Plasmid

    #33090

    Depositor

    Kunliang Guan

    Article

    Zhao et al Genes Dev. 2007 Nov 1. 21(21):2747-61.

    Insert

    YAP (YAP1 )
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    S381A

    Promoter

    CMV

    Available since

    Feb. 10, 2012

    Availability

    Academic Institutions and Nonprofits only

13. pCDNA3 Flag MKK7g1(K165A)

    Plasmid

    #14675

    Depositor

    Roger Davis

    Article

    Tournier et al Mol Cell Biol. 1999 Feb . 19(2):1569-81.

    Insert

    MKK7g1(K165A) (Map2k7 Mouse)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Lys-165Ala

    Promoter

    Available since

    July 25, 2007

    Availability

    Academic Institutions and Nonprofits only

14. pcDNA Flag Yap1 Y357E

    Plasmid

    #18883

    Depositor

    Yosef Shaul

    Article

    Levy et al Mol Cell. 2008 Feb 15. 29(3):350-61.

    Insert

    Yap1 Y357E (YAP1 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Y357E

    Promoter

    Available since

    Aug. 14, 2008

    Availability

    Academic Institutions and Nonprofits only

    

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15. pGEX-2T FRB Y2105A

    Plasmid

    #68726

    Purpose

    Point mutation Tyr 2105 → Ala in the FKBP12-rapamycin binding (FRB) domain of mTOR

    Depositor

    Jie Chen

    Article

    Vilella-Bach et al J Biol Chem. 1999 Feb 12. 274(7):4266-72

    Insert

    FKBP12-rapamycin binding (FRB) domain of MTOR (MTOR Human)
    

    Use

    Tags

    GST-tagged

    Expression

    Bacterial

    Mutation

    FRB domain only aa2015-2114; Y2105A

    Promoter

    Available since

    April 19, 2016

    Availability

    Academic Institutions and Nonprofits only

16. HA SEK AL pcDNA3.1 zeo (+) - SEK1 (A-L)

    Plasmid

    #24653

    Depositor

    Jim Woodgett

    Article

    Yan et al Nature. . 372(6508):798-800.

    Insert

    SEK1 (MAP2K4 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Ser220Ala, Thr224Leu

    Promoter

    Available since

    June 21, 2010

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

17. pCEP-WAF1-ES

    Plasmid

    #16449

    Depositor

    Bert Vogelstein

    Article

    el-Deiry et al Cell. 1993 Nov 19. 75(4):817-25.

    Insert

    WAF1 stop codon mut (CDKN1A Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    stop codon at amino acid 49 instead of tryptophan…

    Promoter

    Available since

    April 7, 2008

    Availability

    Academic Institutions and Nonprofits only

18. pCMV-Flag-YAP-H122L

    Plasmid

    #33086

    Depositor

    Kunliang Guan

    Article

    Zhao et al Genes Dev. 2007 Nov 1. 21(21):2747-61.

    Insert

    YAP (YAP1 )
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    H122L

    Promoter

    CMV

    Available since

    March 21, 2012

    Availability

    Academic Institutions and Nonprofits only

19. TurboID-MEK1

    Plasmid

    #226169

    Purpose

    Used to transiently express a TurboID fusion of the protein kinase MEK1.

    Depositor

    Dustin Maly

    Article

    Simon et al Nat Methods. 2024 Nov;21(11):2094-2106.

    Insert

    Myc-TurboID-MEK1 (MAP2K1 Human)
    

    Use

    Tags

    Myc-TurboID

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pGex-6p2_FANCM_K819R

    Plasmid

    #221380

    Purpose

    Expresses FANCM_K819R in bacterial cells

    Depositor

    Albert Jeltsch

    Article

    Weirich et al Commun Biol. 2024 Jun 8;7(1):707. doi: 1

    Insert

    Fanconi anemia group M protein (FANCM Human)
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Changed lysine 819 to arginine

    Promoter

    tac

    Available since

    June 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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