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pLENTICRISPR-TPI1-sgRNA1

Plasmid

#165949

Purpose

CRISPR-mediated gene perturbation (knock-out) of TPI1

Depositor

Vamsi Mootha

Article

Alexis A. et al Molecular Cell

Insert

TPI1 (TPI1 Human)

Use

Lentiviral

Promoter

U6

Availability

Academic Institutions and Nonprofits only

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pLENTICRISPR-TPI1-sgRNA2

Plasmid

#165950

Purpose

CRISPR-mediated gene perturbation (knock-out) of TPI1

Depositor

Vamsi Mootha

Article

Alexis A. et al Molecular Cell

Insert

TPI1 (TPI1 Human)

Use

Lentiviral

Promoter

U6

Availability

Academic Institutions and Nonprofits only

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pWPI-Neo-SLC7A11-HA

Plasmid

#165958

Purpose

Overexpression of SLC7A11.

Depositor

Vamsi Mootha

Article

Alexis A. et al Molecular Cell

Insert

SLC7A11 (SLC7A11 Human)

Use

Lentiviral

Tags

HA

Promoter

EF1-alpha

Availability

Academic Institutions and Nonprofits only

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ELP-DE30 with tyrosinase sites

Plasmid

#255773

Purpose

Expresses ELP-DE30 with tyrosinase crosslinking sites at the N-terminus

Depositor

Allie Obermeyer

Article

Fisher et al ACS Synth Biol. 2026 Feb 20;15(2):472-48

Insert

ELP-DE30 with tyrosinase sites

Expression

Bacterial

Available Since

June 9, 2026

Availability

Academic Institutions and Nonprofits only

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ELP-DEQ30 with tyrosinase sites

Plasmid

#255774

Purpose

Expresses ELP-DEQ30 with tyrosinase crosslinking sites at the N-terminus

Depositor

Allie Obermeyer

Article

Fisher et al ACS Synth Biol. 2026 Feb 20;15(2):472-48

Insert

ELP-DEQ30 with tyrosinase sites

Expression

Bacterial

Available Since

May 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLV-TRE-DEST-UbC-tTSrtTA-IRES-Neo

Plasmid

#253780

Purpose

Third generation lentiviral expression Gateway cloning destination vector under a Tet-On inducible promoter for expression of a gene of interest linked to neomycin selection by an IRES.

Depositor

Samuel McBrayer

Article

Savani et al Nat Metab. 2026 Apr 29. doi: 10.1038/s42

Type

Empty backbone

Use

Lentiviral

Expression

Mammalian

Available Since

May 1, 2026

Availability

Academic Institutions and Nonprofits only

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pLKO.1-shtRNA-Phe(GAA)-1

Plasmid

#254426

Purpose

Mammalian expression plasmid encoding an shRNA targeting tRNA-Phe(GAA).

Depositor

Rui Su

Article

Ren et al Blood. 2026 Jun 18;147(25):3069-3085. do

Insert

tRNA-Phe (anticodon GAA) 1-4

Use

Lentiviral

Promoter

U6

Available Since

April 9, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINK-EFS-HA-5'-ZNF292

Plasmid

#244424

Purpose

5' AAVLINK plasmid for ZNF292 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

ZNF292 (ZNF292 Human)

Use

AAV

Tags

HA

Promoter

EFS

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINK-EF1alpha-HA-5'-MTOR

Plasmid

#244418

Purpose

5' AAVLINK plasmid for MTOR expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

MTOR (MTOR Human)

Use

AAV

Tags

HA

Promoter

EF1alpha

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINKv1-pCALM1-Cre-3'-ADGRL1-HA

Plasmid

#244399

Purpose

3' AAVLINK plasmid for ADGRL1 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

ADGRL1 (ADGRL1 Human)

Use

AAV

Tags

HA

Promoter

pCALM1

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINK-EF1alpha-HA-5'-EIF4G1

Plasmid

#244400

Purpose

5' AAVLINK plasmid for EIF4G1 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

EIF4G1 (EIF4G1 Human)

Use

AAV

Tags

HA

Promoter

EF1alpha

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINK-EF1alpha-HA-5'-POLR3A

Plasmid

#244390

Purpose

5' AAVLINK plasmid for POLR3A expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

POLR3A (POLR3A Human)

Use

AAV

Tags

HA

Promoter

EF1alpha

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINK-EFS-5'-PLXNA4

Plasmid

#244368

Purpose

5' AAVLINK plasmid for PLXNA4 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

PLXNA4 (PLXNA4 Human)

Use

AAV

Promoter

EFS

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINKv1-pCALM1-Cre-3'-TNRC6B-FLAG

Plasmid

#244361

Purpose

3' AAVLINK plasmid for TNRC6B expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

TNRC6B (TNRC6B Human)

Use

AAV

Tags

FLAG

Promoter

pCALM1

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINKv1-pCALM1-Cre-3'-WNK3-FLAG

Plasmid

#244357

Purpose

3' AAVLINK plasmid for WNK3 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

WNK3 (WNK3 Human)

Use

AAV

Tags

FLAG

Promoter

pCALM1

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINKv1-pCALM1-Cre-3'-LAMB1-FLAG

Plasmid

#244355

Purpose

3' AAVLINK plasmid for LAMB1 expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

LAMB1 (LAMB1 Human)

Use

AAV

Tags

FLAG

Promoter

pCALM1

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pLKO.1-shtRNA-Phe(GAA)-2

Plasmid

#254427

Purpose

Mammalian expression plasmid encoding an shRNA targeting tRNA-Phe(GAA).

Depositor

Rui Su

Article

Ren et al Blood. 2026 Jun 18;147(25):3069-3085. do

Insert

tRNA-Phe (anticodon GAA) 1-4

Use

Lentiviral

Promoter

U6

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pmMBD1.2G (pc2845)

Plasmid

#246849

Purpose

Mammalian expression plasmid of mouse MBD1 N-terminus (aa396-636). C-terminal tagged to GFP.

Depositor

Cristina Cardoso

Article

Zhang et al Nucleic Acids Res. 2017 Apr 25. doi: 10.

Insert

MBD1 (Mbd1 Mouse)

Tags

GFP

Expression

Mammalian

Promoter

CMV

Available Since

April 7, 2026

Availability

Academic Institutions and Nonprofits only

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pGmMBD1.5 (pc3306)

Plasmid

#246852

Purpose

Mammalian expression plasmid of MBD domain and NLS of mouse MBD1. N-terminal tagged to GFP.

Depositor

Cristina Cardoso

Article

Zhang et al Nucleic Acids Res. 2017 Apr 25. doi: 10.

Insert

MBD1 (Mbd1 Mouse)

Tags

GFP

Expression

Mammalian

Promoter

CMV

Available Since

April 7, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG-mch-Tet3CD (pc3339)

Plasmid

#246869

Purpose

Expresses mCherry-tagged catalytic active domain of mouse Tet3 in mammalian cells. N-terminal tagged to mCherry.

Depositor

Cristina Cardoso

Article

Zhang et al Nucleic Acids Res. 2017 Apr 25. doi: 10.

Insert

Tet3 (Tet3 Mouse)

Tags

mCherry

Expression

Mammalian

Promoter

CAG

Available Since

April 7, 2026

Availability

Academic Institutions and Nonprofits only

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