78,128 results

1. pMSCV-mCherry-Syk

   Plasmid

   #50045

   Purpose

   Expression of mCherry-Syk in mammalian cells

   Depositor

   Hidde Ploegh

   Article

   Strijbis et al PLoS Pathog. 2013 Jun;9(6):e1003446. doi

   Insert

   Spleen tyrosine kinase (Syk) (Syk Mouse)
   

   Use

   Retroviral

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   pCMV

   Available Since

   Jan. 13, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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2. pGL3-SEC61B.N-BSD.P2A.miniIAA7.3xFlag

   Plasmid

   #216250

   Purpose

   HDR template to tag endogenous human SEC61B N-terminus with BSD.P2A.miniIAA7.3xFlag

   Depositor

   Elina Ikonen

   Article

   Li et al Genome Biol. 2024 Feb 26;25(1):58. doi:

   Insert

   HDR template for human SEC61B (SEC61B Human, Synthetic, HDR template)
   

   Use

   CRISPR; Hdr template

   Tags

   BSD.P2A.miniIAA7.3xFlag

   Expression

   Mammalian

   Available Since

   March 27, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. AAV-hSYN-eGFP

   Plasmid

   #162512

   Purpose

   AAV vector plasmid expressing enhanced green fluorescent protein (eGFP) under the human synapsin (hSYN) promoter

   Depositor

   Bart Nieuwenhuis

   Article

   Nieuwenhuis et al Gene Ther. 2020 Jun 23. pii: 10.1038/s41

   Insert

   eGFP
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hSYN

   Available Since

   April 20, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pShuttle-Flag-XBP1u

   Plasmid

   #63679

   Purpose

   Adenoviral shuttle vector for XBP1u expression

   Depositor

   Qingbo Xu, Lingfang Zeng

   Article

   Zeng et al Proc Natl Acad Sci U S A. 2009 May 19;10

   Insert

   XBP1 (XBP1 Human)
   

   Use

   Adenoviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   unspliced

   Promoter

   CMV

   Available Since

   March 23, 2015

   Availability

   Academic Institutions and Nonprofits only

5. pDONR221-SLC16A1_STOP

   Plasmid

   #161100

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   SLC16A1 (SLC16A1 Human)
   

   Expression

   Mammalian

   Available Since

   June 21, 2021

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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6. pMSCVhyg-DEST

   Plasmid

   #119747

   Purpose

   Allows Gateway cloning of gene of interest into retroviral pMSCV vector (with Hygromycin resistance)

   Depositor

   Andrew Jackson, Martin Reijns

   Type

   Empty backbone

   Use

   Retroviral

   Expression

   Mammalian

   Available Since

   Feb. 5, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pKLV2.2-mU6gRNA5(SapI)-hU6gRNA5(BbsI)-PGKpuroBFP-W

   Plasmid

   #72667

   Purpose

   Lentiviral dual CRISPR gRNA expression vector (mouse U6 and human U6 promoters)

   Depositor

   Kosuke Yusa

   Article

   Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

   Insert

   mU6gRNA cassette, hU6gRNA cassette, PGKpuroBFP cassette, WPRE
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Oct. 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. pVITRO1-M80-F2-IgG1/κ

   Plasmid

   #50383

   Purpose

   Expresses human IgG1/κ antibody isotype with unknown specificity. Useful vector for cloning of human antibodies with kappa light chain

   Depositor

   Andrew Beavil

   Article

   Dodev et al Sci Rep. 2014 Jul 30;4:5885. doi: 10.103

   Inserts

   human Gamma 1 heavy chain expression cassette with unknown specificity
   human Kappa light chain expression cassette with unknown specificity
   

   Expression

   Mammalian

   Promoter

   Mouse Elongation Factor 1 Alpha and Rat Elongatio…

   Available Since

   Jan. 27, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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9. PINK1-SmBiT Vector

   Plasmid

   #238782

   Purpose

   Express PINK1-SmBiT Fusion Protein in Mammalian Cells under a CMV promoter

   Depositor

   Promega Corporation

   Has Service

   DNA

   Insert

   PINK1 (PINK1 Human)
   

   Tags

   SmBiT

   Expression

   Mammalian

   Mutation

   None

   Promoter

   CMV

   Available Since

   Sept. 14, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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10. p2T-TetON-Hygro-Arhgef11-Cry2-mCh

    Plasmid

    #240798

    Purpose

    Dox-inducible expression of Arhgef11-Cry2-mCherry

    Depositor

    Hans Clevers

    Article

    Krueger et al Science. 2025 Sep 4;389(6764):eadr8753.

    Insert

    Arhgef11-Cry2-mCherry
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Mutation

    none

    Promoter

    TRE

    Available Since

    Sept. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pFUW-TetO-NOTCH2

    Plasmid

    #207193

    Purpose

    doxycycline-inducible expression of Human NOTCH2 in mammalian cells

    Depositor

    Filipe Pereira

    Article

    Henriques-Oliveira et al Immunity. 58, 1-20. October 2025.

    Insert

    pFUW-TetO-NOTCH2
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. ACBE-NW

    Plasmid

    #240624

    Purpose

    A-to-C base editor with narrowed editing window

    Depositor

    Tingting Jiang

    Article

    Valdez et al Nat Commun. 2025 Aug 30;16(1):8115. doi:

    Insert

    TadA8e(N108Q, M151C, Q154Y)-nCas9 (D10A)-mAAG
    

    Use

    CRISPR

    Expression

    Mammalian

    Mutation

    TadA8e(N108Q, M151C, Q154Y),Cas9 (D10A),mAAG (R16…

    Available Since

    Aug. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLentiCCAT1-Red

    Plasmid

    #226521

    Purpose

    CCAT1 transgene with fluorescent protein mKate2

    Depositor

    Neville Sanjana

    Article

    Caragine et al Nat Commun. 2025 Feb 13;16(1):1611. doi:

    Insert

    EF1a_mKate2_CMV_CCAT1 (CCAT1 Human)
    

    Use

    Lentiviral

    Tags

    mKate2

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCDH-3_Flag-YTHDF2

    Plasmid

    #238975

    Purpose

    Expresses YTHDF2

    Depositor

    Jianjun Chen

    Article

    Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.

    Insert

    YTHDF2 (YTHDF2 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. lenti_hEF1a_rtTA-2A-SOX2-2A-KLF4-2A-cMYC

    Plasmid

    #229545

    Purpose

    Lentiviral construct to express rtTA and SKM proteins

    Depositor

    Domitilla Del Vecchio

    Article

    Ilia et al Sci Adv. 2023 Dec;9(48):eadg8495. doi: 1

    Insert

    rTetR-NLS-VP64-P2A-Sox2-T2A-Klf4-E2A-Myc (SOX2 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    hEF1a

    Available Since

    Jan. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pRK5 BMPS WT-TEV-6xHis

    Plasmid

    #204837

    Purpose

    Mammalian expression of recombinant BMPS WT

    Depositor

    Monther Abu-Remaileh

    Article

    Medoh et al Science. 2023 Sep 15;381(6663):1182-1189

    Insert

    CLN5 (CLN5 Human)
    

    Tags

    6xHis

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Nov. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pPB_EF1a_Gag-EIF4E-TM

    Plasmid

    #212658

    Purpose

    piggyBac vector to express an MLV Gag-EIF4E fusion protein (W56L, W102L, W166L mutations installed into EIF4E)

    Depositor

    Paul Blainey

    Article

    Najia et al bioRxiv 2024.10.01.616098

    Insert

    MLV Gag (UniProt ID: P03332) (gag MoMLV)
    

    Use

    Piggybac

    Tags

    EIF4E (W56L, W102L, W166L)

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    Nov. 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. WT_S1-H1

    Plasmid

    #218392

    Purpose

    3-exon minigene, with SRSF1 motif-rich middle exon, and hnRNPA1 motif-rich region in second intron

    Depositor

    Oded Regev

    Insert

    Modified CHO DHFR minigene
    

    Expression

    Mammalian

    Promoter

    tetracycline-responsive promoter

    Available Since

    June 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. MUT_S1-H1

    Plasmid

    #218394

    Purpose

    3-exon minigene, with SRSF1 motif-rich middle exon, hnRNPA1 motif-rich region in second intron, and AG>GG mutation in final 3' splice site

    Depositor

    Oded Regev

    Insert

    Modified CHO DHFR minigene
    

    Expression

    Mammalian

    Promoter

    tetracycline-responsive promoter

    Available Since

    May 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pcDNA3.4_1G11F2-3 heavy chain

    Plasmid

    #198253

    Purpose

    recombinant expression of heavy chain of monoclonal anti-AMP antibody 1G11F2-3

    Depositor

    Aymelt Itzen

    Article

    Hopfner et al iScience. 2020 Nov 13;23(12):101800. doi

    Insert

    heavy chain of monoclonal anti-AMP antibody 1G11F2-3 (mouse IgG2b)
    

    Tags

    IL10 signal peptide

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    May 5, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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