We narrowed to 5,828 results for: ATC

1. Myc-Bnip3-T181A

   Plasmid

   #197556

   Purpose

   Mammalian expression of myc-tagged mouse Bnip3 with an alanine substitution of threonine-181. Based on Myc-Bnip3FL (#100796)

   Depositor

   Joseph Gordon

   Article

   Martens et al Cell Death Dis. 2021 Nov 26;12(12):1105.

   Insert

   BCL2 Interacting Protein 3 (Bnip3 Mouse)
   

   Use

   Tags

   Myc

   Expression

   Mammalian

   Mutation

   Threonine 181 changed to alanine

   Promoter

   CMV

   Available since

   March 1, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLKO.1-TRC.mKO2_shARL4C.1

   Plasmid

   #110320

   Purpose

   TRCN0000048179 (Target GTCCCTGCATATCGTCATGTT), silence human ARL4C gene and express monomeric Kusabira-Orange2

   Depositor

   Sandra Martha Gomes Dias

   Article

   Quintero et al BMC Cancer. 2017 Nov 7;17(1):727. doi: 1

   Insert

   ARL4C (ARL4C Homo sapiens, Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   RNA polymerase III promoter for human U6 snRNA fo…

   Available since

   Aug. 20, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. MYLK gRNA (BRDN0001147172)

   Plasmid

   #77021

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MYLK

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MYLK (MYLK Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. pU6-pegRNA-LRRK2-G2019S-3b

   Plasmid

   #180433

   Purpose

   Transiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cells

   Depositor

   Frank Soldner

   Article

   Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

   Insert

   ncRNA targeting LRRK2-G2019S (LRRK2 Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   LRRK2-G2019S

   Promoter

   U6

   Available since

   Availability

   Academic Institutions and Nonprofits only

   

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5. pU6-pegRNA-LRRK2-G2019S-3c

   Plasmid

   #180434

   Purpose

   Transiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cells

   Depositor

   Frank Soldner

   Article

   Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

   Insert

   ncRNA targeting LRRK2-G2019S (LRRK2 Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   LRRK2-G2019S

   Promoter

   U6

   Available since

   Availability

   Academic Institutions and Nonprofits only

   

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6. pU6-pegRNA-LRRK2-G2019S-3d

   Plasmid

   #180435

   Purpose

   Transiently expressing a pegRNA to introduce LRRK2-G2019S mutation in human cells

   Depositor

   Frank Soldner

   Article

   Li et al Elife. 2022 Sep 7;11:e79208. doi: 10.755

   Insert

   ncRNA targeting LRRK2-G2019S (LRRK2 Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   LRRK2-G2019S

   Promoter

   U6

   Available since

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLKO-Tet-On-YAP1-shRNA1

   Plasmid

   #176846

   Purpose

   lentiviral vector for doxycycline-inducible human YAP1 knockdown

   Depositor

   Roland Friedel

   Article

   Junqueira Alves et al Nat Commun. 2021 Oct 14;12(1):6019. doi:

   Insert

   YAP1-Sh1 (YAP1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Nov. 5, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. sgYAP-TAZ-2

   Plasmid

   #229452

   Purpose

   knockout of YAP1 and WWTR1 (TAZ)

   Depositor

   Christopher Vakoc

   Article

   Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

   Insert

   sgYAP-TAZ-2 (YAP1, WWTR1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6;bU6;EFS

   Available since

   Jan. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pTRIPZ-p21-HA(RxL)

   Plasmid

   #215111

   Purpose

   Expresses p21-HA(RxL) in mammalian cells from an inducible lentiviral vector.

   Depositor

   Michele Pagano

   Article

   Rona et al Mol Cell. 2024 Feb 29:S1097-2765(24)0012

   Insert

   CDKN1A (CDKN1A Human)
   

   Use

   Lentiviral

   Tags

   HA

   Expression

   Mammalian

   Mutation

   p21(RxL) denotes mutations: R19A, R20A, L21A, F22…

   Promoter

   CMV (Tet inducible)

   Available since

   April 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pDNA5-FRT/TO-FLAG-TONSL

    Plasmid

    #221011

    Purpose

    mammalian expression vector of Flag tagged TONSL siRNA resistant

    Depositor

    Daniel Durocher

    Article

    O'Donnell et al Mol Cell. 2010 Nov 24;40(4):619-31. doi:

    Insert

    TONSL (TONSL Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    silent mutations in TONSL: 5’-gaATtAgaTCtaTCGatga…

    Promoter

    CMV

    Available since

    June 24, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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11. pDNA5-FRT/TO-eGFP-TONSL

    Plasmid

    #221012

    Purpose

    mammalian expression vector of eGFP tagged TONSL siRNA resistant

    Depositor

    Daniel Durocher

    Article

    O'Donnell et al Mol Cell. 2010 Nov 24;40(4):619-31. doi:

    Insert

    TONSL (TONSL Human)
    

    Use

    Tags

    eGFP

    Expression

    Mammalian

    Mutation

    silent mutations in TONSL: 5’-gaATtAgaTCtaTCGatga…

    Promoter

    CMV

    Available since

    June 24, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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12. pTRIPZ-p21-HA(dPCNA)

    Plasmid

    #215112

    Purpose

    Expresses p21-HA(dPCNA) in mammalian cells from an inducible lentiviral vector.

    Depositor

    Michele Pagano

    Article

    Rona et al Mol Cell. 2024 Feb 29:S1097-2765(24)0012

    Insert

    CDKN1A (CDKN1A Human)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Mutation

    p21(dPCNA) denotes mutations M147A, D149A, F150A.

    Promoter

    CMV (Tet inducible)

    Available since

    April 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. AAV-U6-sgPlxnb2-KO-4-EF1a-LibVec

    Plasmid

    #239600

    Purpose

    expresses guide#4 to knock-out mouse Plxnb2, via CRISPR-Cas9

    Depositor

    Andreas Moor

    Article

    Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

    Insert

    Plxnb2 (Plxnb2 Mouse)
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. p21(dPCNA)-mCerulean-NeoR

    Plasmid

    #215082

    Purpose

    Expressesp21(dPCNA)-mCerulean in mammalian cells.

    Depositor

    Michele Pagano

    Article

    Rona et al Mol Cell. 2024 Feb 29:S1097-2765(24)0012

    Insert

    CDKN1A (CDKN1A Human)
    

    Use

    Tags

    mCerulean

    Expression

    Mammalian

    Mutation

    p21(dPCNA) denotes mutations M147A, D149A, F150A.

    Promoter

    CMV

    Available since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. p21(RxL)-mCerulean-NeoR

    Plasmid

    #215081

    Purpose

    Expresses p21(RxL)-mCerulean in mammalian cells.

    Depositor

    Michele Pagano

    Article

    Rona et al Mol Cell. 2024 Feb 29:S1097-2765(24)0012

    Insert

    CDKN1A (CDKN1A Human)
    

    Use

    Tags

    mCerulean

    Expression

    Mammalian

    Mutation

    p21(RxL) denotes mutations: R19A, R20A, L21A, F22A

    Promoter

    CMV

    Available since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. p21(RxL)-mCerulean-PuroR

    Plasmid

    #215078

    Purpose

    Expresses p21(RxL)-mCerulean in mammalian cells from a retroviral vector.

    Depositor

    Michele Pagano

    Article

    Rona et al Mol Cell. 2024 Feb 29:S1097-2765(24)0012

    Insert

    CDKN1A (CDKN1A Human)
    

    Use

    Retroviral

    Tags

    mCerulean

    Expression

    Mammalian

    Mutation

    p21(RxL) denotes mutations: R19A, R20A, L21A, F22A

    Promoter

    LTR

    Available since

    April 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. p21(dPCNA)-mCerulean-PuroR

    Plasmid

    #215079

    Purpose

    Expresses p21(dPCNA)-mCerulean in mammalian cells from a retroviral vector.

    Depositor

    Michele Pagano

    Article

    Rona et al Mol Cell. 2024 Feb 29:S1097-2765(24)0012

    Insert

    CDKN1A (CDKN1A Human)
    

    Use

    Retroviral

    Tags

    mCerulean

    Expression

    Mammalian

    Mutation

    p21(dPCNA) denotes mutations M147A, D149A, F150A.

    Promoter

    LTR

    Available since

    April 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. px330 Gatad2a sgRNA (for deletion)

    Plasmid

    #110814

    Purpose

    Expressed sgRNA for generating Gatad2a deletion (knockout ) in mouse cell lines

    Depositor

    Jacob Hanna

    Article

    Mor et al Cell Stem Cell. 2018 Sep 6;23(3):412-425

    Insert

    mGataD2a (Gatad2a Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Dec. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLT3REVIR_MARK3 2573

    Plasmid

    #107233

    Purpose

    shRNA 2573. Do not use Evos or Acurri on these cells. Assess by FACS specifically with Venus and DsRed lazers. Tet-ON-all-in-one

    Depositor

    Alex Kentsis

    Article

    Brown et al Cancer Discov. 2018 Apr;8(4):478-497. do

    Insert

    MARK3 shRNA (22 nt) (MARK3 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 28, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. AAV-KrasG13R/sgKras/Cre

    Plasmid

    #99858

    Purpose

    Expresses Cre-recombinase, a barcoded HDR template to introduce a G13R mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.

    Depositor

    Monte Winslow

    Article

    Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:

    Insert

    Kras (Kras Mouse)
    

    Use

    AAV and Cre/Lox

    Tags

    Expression

    Mammalian

    Mutation

    AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…

    Promoter

    Available since

    Dec. 13, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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