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Plasmid#218181PurposeCRISPR tool to target astrocytesDepositorTypeEmpty backboneUseAAV and CRISPRTagsExpressionMutationPromoterAvailable sinceAug. 23, 2024AvailabilityAcademic Institutions and Nonprofits only
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pCMV-Vamp3-pHluorin
Plasmid#190152PurposeExpresses (pH-sensitive) super ecliptic pHluorin-tagged rat Vamp3 for imaging exocytosisDepositorInsertVamp3 (Vamp3 Rat)
UseAAVTagssuperecliptic pHluorinExpressionMammalianMutationPromoterCMVAvailable sinceDec. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
pZac2.1-GfaABC1D-mCherry-hPMCA2w/b
Plasmid#111568PurposeExpresses a plasma membrane calcium pump hPMCA2w/bDepositorUseAAVTagsmCherryExpressionMutationPromoterAvailable sinceSept. 25, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZac2.1 GfaABC1D hM4D mCherry SV40
Plasmid#92286PurposeAAV DREADD expressionDepositorInserthM4D (CHRM4 Human)
UseAAVTagsmCherryExpressionMutationPromoterGfaABC1DAvailable sinceAug. 16, 2017AvailabilityAcademic Institutions and Nonprofits only -
Circular 200,100 (mPCSK9)
Plasmid#170122PurposeAAV vector carrying 2 copies of a guide RNA targeting the mouse PCSK9 mRNA, expressed from human and mouse U6 promotersDepositorInsertCircular 200,100 guide RNA (Pcsk9 Mouse)
UseAAVTagsExpressionMammalianMutationPromoterHuman U6 and mouse U6Available sinceFeb. 11, 2022AvailabilityAcademic Institutions and Nonprofits only -
Circular 200,100 (mIDUA)
Plasmid#170123PurposeAAV vector carrying 2 copies of a guide RNA targeting the mouse IDUA mRNA, expressed from human and mouse U6 promotersDepositorInsertCircular 200,100 guide RNA (Idua Mouse)
UseAAVTagsExpressionMammalianMutationPromoterHuman U6 and mouse U6Available sinceFeb. 11, 2022AvailabilityAcademic Institutions and Nonprofits only -
pEMS2022
Plasmid#49129PurposeAAV plasmid with DBH promoter (PRS2/3:Con) driving expression of iCre.DepositorInsertssAAV-PRS2/3:Con-iCre
UseAAVTagsExpressionMammalianMutationPromoterDBHAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pZac2.1 GfaABC1D hM3D mCherry SV40
Plasmid#92284PurposeAAV DREADD expressionDepositorInserthM3D (CHRM3 Human)
UseAAVTagsmCherryExpressionMutationPromoterGfaABC1DAvailable sinceAug. 16, 2017AvailabilityAcademic Institutions and Nonprofits only -
pSaCas9-1xPP7-2x3'UTR
Plasmid#122947PurposeFor expressing SaCas9 mRNA with one copy of PP7 aptamer and 2 copies of HBB 3' UTRDepositorInsertSaCas9-PP7-HBB 3' UTR
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceMay 15, 2019AvailabilityAcademic Institutions and Nonprofits only -
pDF0430 huDisCas7-11-S1006-GGGS-D1221-U6-pro-Gluc
Plasmid#186987PurposeAAV transgene plasmid for Cas7-11-S1006-GGGS-D1221, with U6 promoter-driven expression of Gluc crRNA guideDepositorInsertcas7-11-s1006-gggs-d122, Gluc crRNA guide
UseAAVTagsExpressionMutations1006-gggs-d1221 deletionPromoterAvailable sinceSept. 6, 2022AvailabilityAcademic Institutions and Nonprofits only -
pEMS1988
Plasmid#49119PurposeAAV plasmid with CAGGS promoter driving expression of iCre.DepositorInsertssAAV-CAGGS-iCre
UseAAVTagsExpressionMammalianMutationPromoterCAGGSAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pSaCas9-1xms2-2x3’UTR
Plasmid#122946PurposeFor expressing SaCas9 mRNA with one copy of MS2 aptamer and 2 copies of HBB 3' UTRDepositorInsertSaCas9-MS2-HBB 3' UTR
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceMarch 26, 2019AvailabilityAcademic Institutions and Nonprofits only -
pDF0584 huDisCas7-11 S1006-GGGS-D1221 U6-NT guide
Plasmid#186993PurposeAAV transgene plasmid for Cas7-11-S1006-GGGS-D1221, with U6 promoter-driven expression of non-targeting crRNA guideDepositorInsertcas7-11-s1006-gggs-d122, non-targeting crRNA guide
UseAAVTagsExpressionMutations1006-gggs-d1221 deletionPromoterAvailable sinceSept. 27, 2022AvailabilityAcademic Institutions and Nonprofits only -
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pZac2.1 SV40-CMV-SaCas9-3xNLS
Plasmid#78601PurposeAAV vector containing SaCas9DepositorInsertSV40-CMV-SaCas9-3xNLS
UseAAV and CRISPRTagsHA tagExpressionMammalianMutationPromoterSV40, CMV promotersAvailable sinceDec. 2, 2017AvailabilityAcademic Institutions and Nonprofits only -
pZac2.1 U6-SaDMDR7-U6-SaDMDL2
Plasmid#78603PurposeAAV vector containing gRNAs (for SaCas9) targeting Dmd introns 22 and 23DepositorInsertU6-SaDMDR7-U6-SaDMDL2
UseAAV and CRISPRTagsExpressionMammalianMutationPromoterU6Available sinceOct. 27, 2017AvailabilityAcademic Institutions and Nonprofits only -
pEMS2021
Plasmid#49128PurposeAAV plasmid with DCX (Ple302) promoter driving expression of iCre.DepositorInsertssAAV-Ple302-iCre
UseAAVTagsExpressionMammalianMutationPromoterDCXAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
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pDF0582 huDisCas7-11 R1045-GGGS-R1122 U6-NT guide
Plasmid#186991PurposeAAV transgene plasmid for Cas7-11-R1045-GGGS-R1122, with U6 promoter-driven expression of non-targeting crRNA guideDepositorInsertcas7-11-r1045-gggs-r1122, non-targeting crRNA guide
UseAAVTagsExpressionMutationr1045-gggs-r1122 deletionPromoterAvailable sinceSept. 6, 2022AvailabilityAcademic Institutions and Nonprofits only -
pEMS1995
Plasmid#49125PurposeAAV plasmid with GPR88 (Ple94) promoter driving expression of iCre.DepositorInsertssAAV-Ple94-iCre
UseAAVTagsExpressionMammalianMutationPromoterGPR88Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS1997
Plasmid#49127PurposeAAV plasmid with SLC6A4 (Ple198) promoter driving expression of iCre.DepositorInsertssAAV-Ple198-iCre
UseAAVTagsExpressionMammalianMutationPromoterSLC6A4Available sinceMay 7, 2014AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2143
Plasmid#104356PurposeAAV plasmid with smCBA promoter driving expression of emerald GFP (EmGFP) reporter. Contains WPRE.DepositorInsertssAAV-smCBA-EmGFP-WPRE
UseAAVTagsExpressionMutationPromotersmCBAAvailable sinceJuly 10, 2019AvailabilityAcademic Institutions and Nonprofits only -
pEMS2159
Plasmid#70120PurposePromoterless AAV plasmid with MCS to insert promoter for expression of iCre. Contains WPRE.DepositorInsertssAAV-MCS-iCre-WPRE
UseAAVTagsExpressionMammalianMutationPromoterPromoterlessAvailable sinceMay 12, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2031
Plasmid#49134PurposeAAV plasmid with OLIG1 (Ple305) promoter driving expression of iCre.DepositorInsertssAAV-Ple305-iCre
UseAAVTagsExpressionMammalianMutationPromoterOLIG1Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pZac2.1 U6-SaAi9L-U6-SaAi9R
Plasmid#78604PurposeAAV vector containing gRNAs (for SaCas9) targeting Ai9 stop cassetteDepositorInsertgRNAs for SaCas9 targeting Ai9 locus
UseAAV and CRISPRTagsExpressionMammalianMutationPromoterU6Available sinceDec. 14, 2017AvailabilityAcademic Institutions and Nonprofits only -
pEMS1996
Plasmid#49126PurposeAAV plasmid with UGT8 (Ple267) promoter driving expression of iCre.DepositorInsertssAAV-Ple267-iCre
UseAAVTagsExpressionMammalianMutationPromoterUGT8Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS1977
Plasmid#49109PurposeAAV plasmid with C8ORF46 (Ple251) promoter driving expression of iCre.DepositorInsertssAAV-Ple251-icre
UseAAVTagsExpressionMammalianMutationPromoterC8ORF46Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2157
Plasmid#70118PurposePromoterless AAV plasmid with MCS to insert promoter for expression of EmGFP. Contains WPRE.DepositorInsertssAAV-MCS-EmGFP-WPRE
UseAAVTagsExpressionMammalianMutationPromoterPromoterlessAvailable sinceMay 12, 2016AvailabilityAcademic Institutions and Nonprofits only -
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pEMS1980
Plasmid#49111PurposePromoterless AAV plasmid with MCS to insert promoter for expression of iCre.DepositorInsertssAAV-MCS-iCre
UseAAVTagsExpressionMammalianMutationPromoterPromoterlessAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS1993
Plasmid#49123PurposeAAV plasmid with OLIG1 (Ple304) promoter driving expression of iCre.DepositorInsertssAAV-Ple304-iCre
UseAAVTagsExpressionMammalianMutationPromoterOLIG1Available sinceMay 6, 2014AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2158
Plasmid#70119PurposePromoterless AAV plasmid with MCS to insert promoter for expression of EmGFP.DepositorInsertssAAV-MCS-EmGFP
UseAAVTagsExpressionMammalianMutationPromoterPromoterlessAvailable sinceMay 12, 2016AvailabilityAcademic Institutions and Nonprofits only -
pEMS2117
Plasmid#49142PurposeAAV plasmid with smCBA promoter driving expression of iCre.DepositorInsertssAAV-smCBA-iCre
UseAAVTagsExpressionMammalianMutationPromotersmCBAAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS1983
Plasmid#49114PurposeAAV plasmid with PITX3 (Ple253) promoter driving expression of iCre.DepositorInsertssAAV-Ple253-iCre
UseAAVTagsExpressionMammalianMutationPromoterPITX3Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS1989
Plasmid#49120PurposeAAV plasmid with CAGGS promoter driving expression of iCre. Contains WPRE.DepositorInsertssAAV-CAGGS-iCre-WPRE
UseAAVTagsExpressionMammalianMutationPromoterCAGGSAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS1984
Plasmid#49115PurposeAAV plasmid with PITX3 (Ple253) promoter driving expression of iCre. Contains WPRE.DepositorInsertssAAV-Ple253-iCre-WPRE
UseAAVTagsExpressionMammalianMutationPromoterPITX3Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2058
Plasmid#49136PurposeAAV plasmid with CAGGS promoter driving expression of EmGFP. Contains WPRE.DepositorInsertssAAV-CAGGS-emGFP-WPRE
UseAAVTagsExpressionMammalianMutationPromoterCAGGSAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS1978
Plasmid#49110PurposeAAV plasmid with C8ORF46 (Ple251) promoter driving expression of iCre. Contains WPRE.DepositorInsertssAAV-Ple251-icre-WPRE
UseAAVTagsExpressionMammalianMutationPromoterC8ORF46Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2026
Plasmid#49133PurposeAAV plasmid with TNNT1-B (Ple301) promoter driving expression of iCre.DepositorInsertssAAV-Ple301-iCre
UseAAVTagsExpressionMammalianMutationPromoterTNNT1-BAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pDF0428 huDisCas7-11-R1045-GGGS-R1122-U6-pro-Gluc
Plasmid#186985PurposeAAV transgene plasmid for Cas7-11-R1045-GGGS-R1122, with U6 promoter-driven expression of Gluc crRNA guideDepositorInsertcas7-11-r1045-gggs-r1122, Gluc crRNA guide
UseAAVTagsExpressionMutationr1045-gggs-r1122 deletionPromoterAvailable sinceSept. 6, 2022AvailabilityAcademic Institutions and Nonprofits only -
pEMS2023
Plasmid#49130PurposeAAV plasmid with hs1218 promoter driving expression of iCre.DepositorInsertssAAV-hs1218-iCre
UseAAVTagsExpressionMammalianMutationPromoterhs1218Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2024
Plasmid#49131PurposeAAV plasmid with hs671 promoter driving expression of iCre.DepositorInsertssAAV-hs671-iCre
UseAAVTagsExpressionMammalianMutationPromoterhs671Available sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2025
Plasmid#49132PurposeAAV plasmid with NOV (Ple303) promoter driving expression of iCre.DepositorInsertssAAV-Ple303-iCre
UseAAVTagsExpressionMammalianMutationPromoterNOVAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
pEMS2050
Plasmid#49135PurposeAAV plasmid with CAGGS promoter driving expression of EmGFP.DepositorInsertssAAV-CAGGS-emGFP
UseAAVTagsExpressionMammalianMutationPromoterCAGGSAvailable sinceMay 10, 2016AvailabilityIndustry, Academic Institutions, and Nonprofits -
GFP pA_EB_CAGW
Plasmid#92154PurposeAAV construct encoding GFP controlDepositorInsertEGFP
UseAAVTagsExpressionMammalianMutationPromoterCAGWAvailable sinceApril 20, 2018AvailabilityAcademic Institutions and Nonprofits only -
hSyn-FAS-DO-ReaChR-mCitrine-WPRE
Plasmid#64035PurposeExpresses ReaChR under hSyn promoter. FAS-DO turns off expression in Cre-positive cells. FAS is compatible with other traditional Flex/DIO constructsDepositorInserthSyn-FAS-DO-ReaChR-mCitrine-WPRE
UseAAVTagsReaChR tagged with mCitrineExpressionMammalianMutationPromoterhSynAvailable sinceMay 27, 2015AvailabilityAcademic Institutions and Nonprofits only -
EF1a-DIO-PSAML-141F,Y115F- GlyR-2A-FusionRed
Plasmid#226590PurposePharmacologically Selective Actuator Module, chimeric ligand-gated ion channels that can be used to manipulate electrophysiological activity.DepositorInsertPSAML-141F,Y115F-GlyR
UseAAVTagsP2A-Fusion RedExpressionMammalianMutationPromoterEF1aAvailable sinceNov. 1, 2024AvailabilityAcademic Institutions and Nonprofits only -
pGEARBOCS-v0
Plasmid#196495PurposeCRISPR tool to target astrocytesDepositorTypeEmpty backboneUseAAV and CRISPRTagsExpressionMammalianMutationPromoterAvailable sinceAug. 23, 2024AvailabilityAcademic Institutions and Nonprofits only -
pgfaABC1D-mCherry-CAAX
Plasmid#196488PurposeTo over express mCherry-CAAX under gfaABC1D promoter in astrocytesDepositorInsertmCherry-CAAX
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceAug. 23, 2024AvailabilityAcademic Institutions and Nonprofits only