We narrowed to 17,819 results for: Mut

1. pRegev_S2.39U>G.51A>C

   Plasmid

   #204165

   Purpose

   pRegev_S2 with double mutations that restore secondary structure.

   Depositor

   Oded Regev

   Article

   Liao et al Proc Natl Acad Sci U S A. 2023 Oct 10;12

   Insert

   Exon S2 with 39U>G and 51A>C mutations in beta globin splicing minigene
   

   Use

   Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   39U>G and 51A>C mutations

   Promoter

   Truncated CAG

   Available Since

   Aug. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pRegev_S5.49C>A

   Plasmid

   #204175

   Purpose

   pRegev_S5 with single mutation that disrupts secondary structure.

   Depositor

   Oded Regev

   Article

   Liao et al Proc Natl Acad Sci U S A. 2023 Oct 10;12

   Insert

   Exon S5 with 49C>A mutation in beta globin splicing minigene
   

   Use

   Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   49C>A mutation

   Promoter

   Truncated CAG

   Available Since

   Aug. 23, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pRegev_S5.49C>A.59G>U

   Plasmid

   #204177

   Purpose

   pRegev_S5 with double mutations that restore secondary structure.

   Depositor

   Oded Regev

   Article

   Liao et al Proc Natl Acad Sci U S A. 2023 Oct 10;12

   Insert

   Exon S5 with 49C>A and 59G>U mutations in beta globin splicing minigene
   

   Use

   Synthetic Biology

   Tags

   Expression

   Mammalian

   Mutation

   49C>A and 59G>U mutations

   Promoter

   Truncated CAG

   Available Since

   Aug. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. Venus-Bik-GG153AA-pEGFP-C1

   Plasmid

   #177427

   Purpose

   To express Venus fused to the N-terminus of the Bcl-2 family protein, Bik, with G153A,G154A mutations in membrane binding region. Mutations made to Addgene #166737.

   Depositor

   David Andrews

   Insert

   Bik, Bcl-2-interacting killer, or Apoptosis inducer NBK (BIK Human)
   

   Use

   Tags

   Venus

   Expression

   Mammalian

   Mutation

   Glycines 153 and 154 mutated to alanine

   Promoter

   CMV

   Available Since

   Jan. 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. human KANK2-A670V Ankyrin Repeats pET151

   Plasmid

   #164055

   Purpose

   Expresses human KANK2 Ank domain - A670V mutant in bacterial cells

   Depositor

   Ben Goult

   Insert

   Kidney Ankyrin Repeat-Containing Protein 2 A670V mutant (KANK2 Human)
   

   Use

   Tags

   His-tag, TEV cleavage site

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available Since

   Oct. 6, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pKP933

   Plasmid

   #167657

   Purpose

   Express colicinB-His6, V21C, M261C

   Depositor

   Kathleen Postle

   Article

   Skare et al J Bacteriol. 1989 Aug;171(8):4442-7. doi

   Insert

   cba-his6 V21C, M261C
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   cba-his6 with V21C, M261C mutations

   Promoter

   Available Since

   July 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. Flag-M4-AR-K222A

   Plasmid

   #171257

   Purpose

   Mammalian expression of 3xFlag-tagged human androgen receptor Lysine mutant: AR-Lys222Ala mutant (AR-K222A)

   Depositor

   Steven Balk

   Insert

   3xFlag-tagged human androgen receptor Lys222Ala mutant (AR Human)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   AR-Lys222Ala (AR-K222A)

   Promoter

   CMV

   Available Since

   June 25, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCL33-decoder

   Plasmid

   #159451

   Purpose

   Insert: Pfus1mut-tetR-nls-malE-tCyc1. TetR-NLS-MBP (Azizoglu et al, bioRxiv 2019) is inducible by alpha-factor. Backbone: pRG203MX (addgene). Marker: His3.

   Depositor

   Joerg Stelling

   Article

   Lormeau et al Nat Commun. 2021 Mar 25;12(1):1886. doi:

   Insert

   Pfus1mut-tetR-nls-malE-tCyc1
   

   Use

   Synthetic Biology

   Tags

   Expression

   Yeast

   Mutation

   Promoter

   Pfus1mut

   Available Since

   Dec. 11, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pRS314_U6_A34G_A35G

   Plasmid

   #81232

   Purpose

   U6 telestem mutant (A34G/A35G) for in vivo studies

   Depositor

   Aaron Hoskins

   Article

   Rodgers et al Nucleic Acids Res. 2016 Dec 15;44(22):10

   Insert

   U6 RNA with A34G/A35G mutation (snR6 Budding Yeast)
   

   Use

   Tags

   Expression

   Yeast

   Mutation

   U6 telestem mutant (A34G/A35G)

   Promoter

   Available Since

   Sept. 1, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pRS314_U6_G96C_A97C

    Plasmid

    #81235

    Purpose

    U6 telestem mutant (G96C/A97C) for in vivo studies

    Depositor

    Aaron Hoskins

    Article

    Rodgers et al Nucleic Acids Res. 2016 Dec 15;44(22):10

    Insert

    U6 RNA with G96C/A97C mutation (snR6 Budding Yeast)
    

    Use

    Tags

    Expression

    Yeast

    Mutation

    U6 telestem mutant (G96C/A97C)

    Promoter

    Available Since

    Sept. 1, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. pRS314_U6_U100C_U101C

    Plasmid

    #81236

    Purpose

    U6 telestem mutant (U100C/U101C) for in vivo studies

    Depositor

    Aaron Hoskins

    Article

    Rodgers et al Nucleic Acids Res. 2016 Dec 15;44(22):10

    Insert

    U6 RNA with U100C_U101C mutation (snR6 Budding Yeast)
    

    Use

    Tags

    Expression

    Yeast

    Mutation

    U6 telestem mutant (G96C/A97C)

    Promoter

    Available Since

    Sept. 1, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCR3.1-CREM2 luc

    Plasmid

    #106460

    Purpose

    luciferase reporter, CMV promoter (CRE site adjacent to NFkB site mutated)

    Depositor

    Georg Weber

    Article

    He et al Biochem Biophys Res Commun. 2004 Aug 13;

    Insert

    luciferase reporter, CMV promoter (CRE site adjacent to NFkB site mutated)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    CRE site adjacent to NFkB site mutated

    Promoter

    Available Since

    Aug. 17, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pOZ-FH-C Bach1 K141A/K142A

    Plasmid

    #73646

    Purpose

    Retroviral expression of Bach1 K141A/K142A mutant (mlh1 binding mutant)

    Depositor

    Sharon Cantor

    Insert

    Bach1 (BACH1 Human)
    

    Use

    Retroviral

    Tags

    FLAG and His

    Expression

    Mammalian

    Mutation

    K141A/K142A ( mlh1 binding mutant)

    Promoter

    unknown

    Available Since

    Jan. 7, 2019

    Availability

    Academic Institutions and Nonprofits only

14. pMLS415

    Plasmid

    #114272

    Purpose

    SapTrap donor vector for point mutagenesis; pENTR-221::syntron(lox2272-119+)

    Depositor

    Erik Jorgensen

    Article

    Schwartz et al MicroPubl Biol. 2018 Jul 29;2018:10.1791

    Insert

    Cbr-Unc-119
    

    Use

    CRISPR and Cre/Lox

    Tags

    Expression

    Mutation

    *please see depositor comment below

    Promoter

    Available Since

    Dec. 17, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. FGFR2 K659M 3xFlag

    Plasmid

    #110112

    Purpose

    expresses FGFR2 with a single amino acid change in mammalian cells

    Depositor

    Martin Fernandez-Zapico

    Insert

    fibroblast growth factor receptor 2 (FGFR2 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    mutated Lysine 659 to Methiionine (K659M)

    Promoter

    CMV

    Available Since

    May 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. FGFR2 E565A 3xFlag

    Plasmid

    #110109

    Purpose

    expresses FGFR2 with a single amino acid change in mammalian cells

    Depositor

    Martin Fernandez-Zapico

    Insert

    fibroblast growth factor receptor 2 (FGFR2 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    mutated Glutamic acid 565 to Alanine (E565A)

    Promoter

    CMV

    Available Since

    May 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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17. FGFR2 K641R 3xFlag

    Plasmid

    #110111

    Purpose

    expresses FGFR2 with a single amino acid change in mammalian cells

    Depositor

    Martin Fernandez-Zapico

    Insert

    fibroblast growth factor receptor 2 (FGFR2 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    mutated Lysine 641 to Arginine (K641R)

    Promoter

    CMV

    Available Since

    May 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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18. FGFR2 N549H 3xFlag

    Plasmid

    #110106

    Purpose

    expresses FGFR2 with a single amino acid change in mammalian cells

    Depositor

    Martin Fernandez-Zapico

    Insert

    fibroblast growth factor receptor 2 (FGFR2 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    mutated Asparagine 549 to Histidine (N549H)

    Promoter

    CMV

    Available Since

    May 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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19. FGFR2 N549K 3xFlag

    Plasmid

    #110107

    Purpose

    expresses FGFR2 with a single amino acid change in mammalian cells

    Depositor

    Martin Fernandez-Zapico

    Insert

    fibroblast growth factor receptor 2 (FGFR2 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    mutated Asparagine 549 to Lysine (N549K)

    Promoter

    CMV

    Available Since

    May 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. FGFR2 L617V 3xFlag

    Plasmid

    #110110

    Purpose

    expresses FGFR2 with a single amino acid change in mammalian cells

    Depositor

    Martin Fernandez-Zapico

    Insert

    fibroblast growth factor receptor 2 (FGFR2 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    mutated Leucine 617 to Valine (L617V)

    Promoter

    CMV

    Available Since

    May 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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