We narrowed to 632 results for: weissman

Showing: 221 - 240 of 632 results

Results per page:

Sort results by:

pTMB398_ZFcharm_Prnp_SMM

Plasmid

#220845

Purpose

AAV genome expressing ZFcharm targeting Prnp; single mismatch self-silencing binding site

Depositor

Jonathan Weissman

Article

Neumann et al Science. 2024 Jun 28;384(6703):ado7082.

Insert

ZFcharm

Use

AAV

Tags

HAtag

Expression

Mammalian

Mutation

N/A

Promoter

EFS

Available Since

June 25, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pTMB303_ZFcharm_Kv1_Prnp_SMM

Plasmid

#220841

Purpose

AAV genome expressing ZFcharm Kv1 targeting Prnp; single mismatch self-silencing binding site

Depositor

Jonathan Weissman

Article

Neumann et al Science. 2024 Jun 28;384(6703):ado7082.

Insert

ZFcharm Kv1

Use

AAV

Tags

HAtag

Expression

Mammalian

Mutation

N/A

Promoter

EFS

Available Since

June 25, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pGM9

Plasmid

#220167

Purpose

Expresses a reporter for an alpha-helical OMM protein

Depositor

Jonathan Weissman

Article

Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

Insert

FUNDC1 (FUNDC1 Human)

Use

Lentiviral

Tags

GFP11

Available Since

June 7, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pGM258

Plasmid

#220176

Purpose

Expresses exogenous C-terminal mutant TTC1 (I271D)

Depositor

Jonathan Weissman

Article

Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

Insert

TTC1 (TTC1 Human)

Use

Lentiviral

Tags

3xFLAG

Mutation

I271D

Available Since

June 7, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pGM133

Plasmid

#220173

Purpose

CRISRPi guide RNA against TTC1

Depositor

Jonathan Weissman

Article

Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

Insert

TTC1 (sgRNA) (TTC1 Human)

Use

Lentiviral

Available Since

June 7, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pGM84

Plasmid

#220172

Purpose

CRISRPi guide RNA against BTF3

Depositor

Jonathan Weissman

Article

Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

Insert

BTF3 (sgRNA) (BTF3 Human)

Use

Lentiviral

Available Since

June 7, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pGM268

Plasmid

#220181

Purpose

Expresses exogenous C-terminal mutant TTC1 (I271D) with an N-terminal sfGFP tag

Depositor

Jonathan Weissman

Article

Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

Insert

TTC1 (TTC1 Human)

Use

Lentiviral

Tags

sfGFP

Mutation

I271D

Available Since

May 22, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pGM295

Plasmid

#220183

Purpose

Expresses exogenous wild-type SEC61B with a C-terminal sfGFP tag

Depositor

Jonathan Weissman

Article

Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

Insert

SEC61B (SEC61B Human)

Use

Lentiviral

Tags

sfGFP

Available Since

May 22, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pGM216

Plasmid

#220175

Purpose

Expresses exogenous TPR mutant TTC1 (R190A_R194A)

Depositor

Jonathan Weissman

Article

Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

Insert

TTC1 (TTC1 Human)

Use

Lentiviral

Tags

3xFLAG

Mutation

R190A + R194A

Available Since

May 22, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pGM209

Plasmid

#220174

Purpose

Expresses exogenous wild-type TTC1

Depositor

Jonathan Weissman

Article

Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

Insert

TTC1 (TTC1 Human)

Use

Lentiviral

Tags

3xFLAG

Available Since

May 22, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCDNA3-SREBP-2-GFP (A1134-1135)

Plasmid

#204203

Purpose

Mammalian expression of SREBP-2

Depositor

Allan Weissman

Article

Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

Insert

SREBP-2 (SREBF2 Human)

Tags

T7x3 and eGFP

Expression

Mammalian

Mutation

Gly to Ala 1134, 1135

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCDNA3-SREBP-2 (STOP)

Plasmid

#204204

Purpose

Mammalian expression of SREBP-2

Depositor

Allan Weissman

Article

Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

Insert

SREBP-2 (SREBF2 Human)

Tags

T7x3

Expression

Mammalian

Mutation

Nonsense mutations after Gly1135

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCDNA3- SREBP-1 (A317-318; L340)

Plasmid

#204195

Purpose

Mammalian expression of SREBP-1 (Isoform 1)

Depositor

Allan Weissman

Article

Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

Insert

SREBP-1 (SREBF1 Human)

Tags

E-tag and T7x2

Expression

Mammalian

Mutation

Gly to Ala 317,318; Gly to Leu 340

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCDNA3- SREBP-1 (A317-318;A341; A1171)

Plasmid

#204196

Purpose

Mammalian expression of SREBP-1 (isoform 1)

Depositor

Allan Weissman

Article

Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

Insert

SREBP-1 (SREBF1 Human)

Tags

E-tag and T7x2

Expression

Mammalian

Mutation

Gly to Ala 317,318,341,1171

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCDNA3-SREBP-1 (A341; A1171)

Plasmid

#204197

Purpose

Mammalian expression of SREBP-1 (isoform 1)

Depositor

Allan Weissman

Article

Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

Insert

SREBP-1a (SREBF1 Human)

Tags

E-tag and T7x2

Expression

Mammalian

Mutation

Gly to Ala 341, 1171

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCDNA3-SREBP-1-GFP (A317-318; A341; A1171)

Plasmid

#204199

Purpose

Mammalian expression of SREBP-1 (isoform 1)

Depositor

Allan Weissman

Article

Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

Insert

SREBP-1 (SREBF1 Human)

Tags

3xHA, eGFP and T7x2

Expression

Mammalian

Mutation

Gly to Ala 317,318,341,1171

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pCDNA3-SREBP-2 (A1134-1135)

Plasmid

#204201

Purpose

Mammalian expression of SREBP-2

Depositor

Allan Weissman

Article

Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

Insert

SREBP-2 (SREBF2 Human)

Tags

T7x3

Expression

Mammalian

Mutation

Gly to Ala 1134 to 1135

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pETDUET-GST AO7RE ∆238-245

Plasmid

#139318

Purpose

GST tagged AO7 encoding aa 126-258 with an internal deletion that results in loss of E2 binding for expression in bacteria

Depositor

Allan Weissman

Article

Li et al J Biol Chem. 2015 Dec 18;290(51):30225-3

Insert

AO7 aa 126-258 (RNF25 Human)

Tags

GST

Expression

Bacterial

Mutation

AO7 cloned into the first multiple cloning site o…

Promoter

T7 promoter-1

Available Since

Dec. 15, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
pCINeo-gp78 Mutant G2BR

Plasmid

#185355

Purpose

Assessing cellular requirement for G2BRgp78

Depositor

Allan Weissman

Article

Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

Insert

gp78 (AMFR Human)

Tags

GST

Expression

Mammalian

Mutation

aa 595-600 KRFLNK to AGAAGG

Available Since

Dec. 5, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
pGEX-6P-1 AUP1 61-410

Plasmid

#185334

Purpose

Bacterial expression of AUP1 with GST fusion protein for binding assays

Depositor

Allan Weissman

Article

Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

Insert

AUP1 (AUP1 Human)

Tags

GST

Expression

Bacterial

Mutation

aa 61-610 only

Available Since

Oct. 23, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge