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CRKL gRNA (BRDN0001145388)

Plasmid

#77508

Purpose

3rd generation lentiviral gRNA plasmid targeting human CRKL

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CRKL (CRKL Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CRKL gRNA (BRDN0001148341)

Plasmid

#77509

Purpose

3rd generation lentiviral gRNA plasmid targeting human CRKL

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CRKL (CRKL Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ALK gRNA (BRDN0001147509)

Plasmid

#77392

Purpose

3rd generation lentiviral gRNA plasmid targeting human ALK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ALK (ALK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ALK gRNA (BRDN0001148180)

Plasmid

#77391

Purpose

3rd generation lentiviral gRNA plasmid targeting human ALK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ALK (ALK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pPRIME-CMV-GFP-shCrh1

Plasmid

#132709

Purpose

Encodes short hairpin RNA (shRNA) #1 that targets the 3’-untranslated region of the rat Crh gene

Depositor

Robert Messing

Article

Pomrenze et al Cell Rep. 2019 Oct 1;29(1):13-21.e4. doi

Insert

shCrh(1) (Crh Rat)

Use

Lentiviral

Promoter

CMV

Available Since

Oct. 31, 2019

Availability

Academic Institutions and Nonprofits only

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pGAL4-DBD-HOXA13-58A-IDR

Plasmid

#145238

Purpose

Expresses fusion of GAL4 DNA-binding domain and HOXA13-58A IDR

Depositor

Denes Hnisz

Article

Basu et al Cell. 2020 May 28;181(5):1062-1079.e30.

Insert

HOXA13-58A-IDR (HOXA13 Human)

Expression

Mammalian

Mutation

A-repeats deleted

Available Since

Sept. 21, 2020

Availability

Academic Institutions and Nonprofits only

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BAM2 X050_pECIA14

Plasmid

#114904

Purpose

Prey vector BAM2 X050_pECIA14 should be used with bait vector BAM2 X050_pECIA2.

Depositor

Youssef Belkhadir

Article

Smakowska-Luzan et al Nature. 2018 Jan 18;553(7688):342-346. d

Insert

AT3G49670 (BAM2 Mustard Weed)

Expression

Insect

Promoter

Metallothionein (Copper-Inducible)

Available Since

March 21, 2019

Availability

Academic Institutions and Nonprofits only

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ALK gRNA (BRDN0001146138)

Plasmid

#77393

Purpose

3rd generation lentiviral gRNA plasmid targeting human ALK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ALK (ALK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ALK gRNA (BRDN0001146667)

Plasmid

#77394

Purpose

3rd generation lentiviral gRNA plasmid targeting human ALK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ALK (ALK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CRKL gRNA (BRDN0001147790)

Plasmid

#77507

Purpose

3rd generation lentiviral gRNA plasmid targeting human CRKL

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CRKL (CRKL Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1_hE2F7mg_2ntmut

Plasmid

#73074

Purpose

human E2F7 minigene (exons 11,12,13/introns cassette) with mutated snord27 binding site

Depositor

Stefan Stamm

Article

Falaleeva et al Proc Natl Acad Sci U S A. 2016 Mar 22;11

Insert

E2F7 (E2F7 Human)

Expression

Mammalian

Mutation

partial gene, exons 11,12,13 spaced by introns, 2…

Available Since

Dec. 7, 2018

Availability

Academic Institutions and Nonprofits only
TDP-43_CTD_L330A

Plasmid

#248879

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with L330A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_L330A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed L330A

Available Since

Jan. 15, 2026

Availability

Academic Institutions and Nonprofits only

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pSico-syn-GFP-TVA-oG-WPRE-bGHpA

Plasmid

#231009

Purpose

Lentiviral helper virus for G-deleted rabies tracing

Depositor

Tomasz Nowakowski

Article

Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

Inserts

Enhanced GFP
TVA (CD320 Chicken)
optimized G

Use

Lentiviral

Promoter

human synapsin I

Available Since

Dec. 16, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_S273C

Plasmid

#248864

Purpose

Expresses MBP-tagged C-terminal domain of TDP-43 with S273C.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_S273C (TARDBP Human)

Tags

6xHis tags-MBP

Expression

Bacterial

Mutation

changed S273C

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_S332A

Plasmid

#248881

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with S332A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_S332A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed S332A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_Q331A

Plasmid

#248880

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with Q331A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_Q331A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed Q331A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_Q343A

Plasmid

#248889

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with Q343A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_Q343A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed Q343A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_Q327A

Plasmid

#248878

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with Q327A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_Q327A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed Q327A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_N319A

Plasmid

#248873

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with N319A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_N319A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed N319A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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TDP-43_CTD_M322A

Plasmid

#248874

Purpose

Expresses 6xHis-tagged C-terminal domain of TDP-43 with M322A.

Depositor

Nicolas Fawzi

Article

Rizuan et al Nat Commun. 2025 Nov 26;16(1):10528. doi

Insert

TDP-43_CTD_M322A (TARDBP Human)

Tags

6xHis-tags

Expression

Bacterial

Mutation

changed M322A

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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