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pCAG_A0A2I0TQP5

Plasmid

#261218

Purpose

Expression of the construct for a RNA transfer vehicle, containing a different membrane binding domain

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

A0A2I0TQP5-SynLnoFlanks-XTEN_HibiT_HA-tdPCP-HE0690

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_MGYP003957870823

Plasmid

#261217

Purpose

Expression of the construct for a RNA transfer vehicle, containing a different membrane binding domain

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

MGYP003957870823-SynLnoFlanks-XTEN_HibiT_HA-tdPCP-HE0690

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_Q9HB21

Plasmid

#261216

Purpose

Expression of the construct for a RNA transfer vehicle, containing a different membrane binding domain

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

Q9HB21-SynLnoFlanks-XTEN_HibiT_HA-tdPCP-HE0690

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_STV-HE0505

Plasmid

#261215

Purpose

Expression of the construct for a RNA transfer vehicle

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

PHPLCdelta-SynLnoFlanks-XTEN_HibiT_HA-tdPCP-HE0505

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_STV-HE0499

Plasmid

#261214

Purpose

Expression of the construct for a RNA transfer vehicle

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

PHPLCdelta-SynLnoFlanks-XTEN_HibiT_HA-tdPCP-HE0499

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_STV-HE0490

Plasmid

#261213

Purpose

Expression of the construct for a RNA transfer vehicle

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

PHPLCdelta-SynLnoFlanks-XTEN_HibiT_HA-tdPCP-HE0490

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_Cas9-NLS-NES-PP7

Plasmid

#261212

Purpose

Cas9-NLS-NES construct to be used as cargo in RNA transfer vehicles

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

Cas9-3xNLS-FLAG-NES_PP7

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_EGFP-PP7

Plasmid

#261211

Purpose

EGFP construct to be used as cargo in RNA transfer vehicles

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

eGFP-PP7

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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EPI-CAG-SauriCas9-ZsGreen-puroR-dualU6-sgRNA

Plasmid

#249830

Purpose

Episomal CAG-SauriCas9-ZsGreen-puroR vector with dual U6 sgRNA cassettes for CRISPR editing in mammalian cells.

Depositor

Bin Yu

Publication

Chen et al Commun Biol. 2025 Dec 29;9(1):159. doi:

Insert

None (Trp53 Mouse)

Use

CRISPR

Expression

Mammalian

Promoter

CAG and U6

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_C-SplitLuc

Plasmid

#261210

Purpose

Generation of a stable expressing cell line with the C part of firefly luciferase

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

pAAVS1-CAG_LgBit-P2A-N6coil-C-gp41-C-Fluc-IRES_PuroR_bpA

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_N-SplitLuc-PP7

Plasmid

#261209

Purpose

N-SplitLuc part of firefly luciferase to be used as cargo in RNA transfer vehicles

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

N-FlucV2-N-gp41-N5coil-PEST-PP7

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_STV-HE0902

Plasmid

#261208

Purpose

Expression of the construct for a RNA transfer vehicle

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

PHPLCdelta-SynLnoFlanks-XTEN_HibiT_HA-tdPCP-HE0902

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG_STV-C8

Plasmid

#261207

Purpose

Expression of the construct for a RNA transfer vehicle

Depositor

Wolfgang Wurst

Publication

Schuhmacher et al Nature. 2026 Sep 2. doi: 10.1038/s41586-

Insert

A0A452QKQ4-SynLnoFlanks-XTEN_HibiT_HA-tdPCP-HE0690

Expression

Mammalian

Promoter

CAG

Available since

Oct. 23, 2026

Availability

Academic Institutions and Nonprofits only

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pCAG-BxB1

Plasmid

#262516

Purpose

Serine recombinase for site-specific DNA integration between attP and attB landing sites.

Depositor

Prashant Mali

Publication

Nourreddine et al Nat Biotechnol. 2026 Jul 1. doi: 10.1038

Insert

Bxb1

Tags

SV40 NLS, HA

Expression

Mammalian

Promoter

CAG

Available since

Oct. 19, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVS1-CAG-KRAB-dCas9-P2A-EGFP-BSD

Plasmid

#262517

Purpose

CRISPRi cassette KRAB(Zim3)-dCas9 into the PPP1R12C locus AAVS1 safe-harbor locus.

Depositor

Prashant Mali

Publication

Nourreddine et al Nat Biotechnol. 2026 Jul 1. doi: 10.1038

Insert

KRAB-dCas9-P2A-EGFP

Use

CRISPR

Tags

EGFP and HA

Expression

Mammalian

Promoter

CAG

Available since

Oct. 16, 2026

Availability

Academic Institutions and Nonprofits only

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PD2529 human αV ecto

Plasmid

#259679

Purpose

Plasmid encoding human integrin αV ectodomain

Depositor

Timothy Springer

Publication

Hao et al MAbs. 2024 Jan-Dec;16(1):2365891. doi: 1

Insert

human integrin αV ectodomain (ITGAV Human)

Tags

CD33 secretion peptide (MPLLLLLPLLWAGALA) and HRV…

Expression

Mammalian

Available since

Oct. 16, 2026

Availability

Academic Institutions and Nonprofits only

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TK4_RCaMP3_Hygro

Plasmid

#259931

Purpose

PiggyBac expression of RCaMP3

Depositor

Beth Stevens

Publication

Morshed et al bioRxiv [Preprint]. 2026 Jun 5:2026.06.0

Insert

RCaMP3

Use

Piggybac

Expression

Mammalian

Promoter

CAG

Available since

Oct. 15, 2026

Availability

Academic Institutions and Nonprofits only

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pPB-CAG-h2-3

Plasmid

#262788

Purpose

Constitutive expression of h2-3 fluorescent protein. Single-color control for tFucci(CA)5 and tFucci(SA)5

Depositor

Courtney Hodges

Publication

Cermakova et al Nucleic Acids Res. 2024 Jan 11;52(1):4-2

Insert

h2-3

Use

Piggybac

Expression

Mammalian

Promoter

CAG

Available since

Oct. 14, 2026

Availability

Academic Institutions and Nonprofits only

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pPB-CAG-AzaleaB5

Plasmid

#262787

Purpose

Constitutive expression of AzaleaB5 fluorescent protein. Single-color control for tFucci(CA)5 and tFucci(SA)5

Depositor

Courtney Hodges

Publication

Cermakova et al Nucleic Acids Res. 2024 Jan 11;52(1):4-2

Insert

AzaleaB5

Use

Piggybac

Expression

Mammalian

Promoter

CAG

Available since

Oct. 14, 2026

Availability

Academic Institutions and Nonprofits only

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PD2529 human β6 full-P2A-mcherry

Plasmid

#260942

Purpose

Plasmid encoding human integrin β6 full-length

Depositor

Timothy Springer

Publication

Hao et al MAbs. 2024 Jan-Dec;16(1):2365891. doi: 1

Insert

integrin beta-6 (ITGB6 Human)

Tags

CD33 secretion peptide and P2A-mCherry

Expression

Mammalian

Promoter

CAG

Available since

Oct. 14, 2026

Availability

Academic Institutions and Nonprofits only

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