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IL2Ralpha-pEGFP-FKBP

Plasmid

#251430

Purpose

Mammalian expression vector for expressing the human interleukin-2 receptor alpha subunit (IL2Ralpha membrane anchor) fused to EGFP and FKBP at the C-terminus

Depositor

Thomas Friedman, Takushi Miyoshi

Article

Miyoshi et al Nat Commun. 2025 Sep 1;16(1):8149. doi:

Insert

Interleukin 2 receptor alpha chain (IL2RA Human)

Tags

EGFP, FKBP

Expression

Mammalian

Available Since

March 3, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC2-TOM20-HK2-3xFLAG

Plasmid

#239245

Purpose

TOM20-HK2 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

TOM20-HK2 (HK2, TOMM20 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the set of silent mutations descr…

Promoter

CMV

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pLJC6-TOM20-HK2-3xFLAG

Plasmid

#239256

Purpose

TOM20-HK2 lentiviral overexpression vector

Depositor

Jason Cantor

Article

Huggler et al Nat Metab. 2026 Jan 16. doi: 10.1038/s42

Insert

TOM20-HK2 (HK2, TOMM20 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Insert contains the set of silent mutations descr…

Promoter

Ubc

Available Since

Jan. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINK-EFS-HA-5'-MED13L

Plasmid

#244294

Purpose

5' AAVLINK plasmid for MED13L expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

MED13L (MED13L Human)

Use

AAV

Tags

HA

Promoter

EFS

Available Since

Dec. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-DIO-PGC-1alpha-IRES-mCitrine

Plasmid

#241791

Purpose

Expression vector for mouse Pgc-1alpha with mCitrine

Depositor

Mary Kay Lobo

Article

Chandra et al Biol Psychiatry. 2017 Apr 1;81(7):564-57

Insert

PGC-1alpha (Ppargc1a Mouse)

Use

AAV

Tags

mCitrine

Promoter

hSyn

Available Since

Nov. 12, 2025

Availability

Academic Institutions and Nonprofits only

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SFFV-MEIS2-Brd 243

Plasmid

#219186

Purpose

Transcription factor MEIS2 with a specific barcode assigned.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

MEIS2 (MEIS2 Human)

Use

Lentiviral

Promoter

The spleen focus-forming virus (SFFV) promoter

Available Since

Oct. 29, 2025

Availability

Academic Institutions and Nonprofits only

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SFFV-HOXD9-Brd 223

Plasmid

#219166

Purpose

Transcription factor HOXD9 with a specific barcode assigned.

Depositor

Filipe Pereira

Article

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

HOXD9 (HOXD9 Human)

Use

Lentiviral

Mutation

Codon optimized

Promoter

The spleen focus-forming virus (SFFV) promoter

Available Since

Oct. 29, 2025

Availability

Academic Institutions and Nonprofits only

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Anti-ANO9/TMEM16J [N443/17R]

Plasmid

#222164

Purpose

Mammalian Expression Plasmid of anti-ANO9/TMEM16J (Human). Derived from hybridoma N443/17.

Depositor

James Trimmer

Article

Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

Insert

Anti-ANO9/TMEM16J (Homo sapiens) recombinant mouse monoclonal antibody. (ANO9 Mouse)

Expression

Mammalian

Promoter

Dual CMV

Available Since

Aug. 13, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1-GSDMD_H270A

Plasmid

#224701

Purpose

Expression of mutated Gasdermin D_H270A (GSDMD_H270A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_H270A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

H270A

Promoter

CMV

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-GSDMD_Q29A

Plasmid

#224702

Purpose

Expression of mutated Gasdermin D_Q29A (GSDMD_Q29A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_Q29A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

Q29A

Promoter

CMV

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-GSDMD_Q29A_H270A

Plasmid

#224703

Purpose

Expression of mutant Gasdermin D_Q29A_H270A (GSDMD_Q29A_H270A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_Q29A_H270A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

Q29A and H270A

Promoter

CMV

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-GSDMD_D275A

Plasmid

#224704

Purpose

Expression of mutated Gasdermin D_D275A (GSDMD_D275A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_D275A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

D275A

Promoter

CVM

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3.1-GSDMD_H270A_D275A

Plasmid

#224705

Purpose

Expression of mutated Gasdermin D_H270A_D275A (GSDMD_D275A) in transfected mammalian cell lines

Depositor

Christopher Overall

Article

Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

Insert

GSDMD_Q29A_H270A (GSDMD Human)

Tags

FLAG

Expression

Mammalian

Mutation

H270A and D275A

Promoter

CMV

Available Since

July 2, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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pKLV2-U6gRNA5(hBIRC2_1k)-PGKpuro2ABFP-W

Plasmid

#208416

Purpose

Lentiviral gRNA plasmid targeting human BIRC2 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

BIRC2 (BIRC2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hBIRC2_2b)-PGKpuro2ABFP-W

Plasmid

#208417

Purpose

Lentiviral gRNA plasmid targeting human BIRC2 gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

BIRC2 (BIRC2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pAG8Ha-FLI1_DBD(276-399_C299S_F362A_S390C)

Plasmid

#188048

Purpose

Expresses His8-FLI1_DBD(276-399_C299S_F362A_S390C) with a TEV site for removal of the His8 tag.

Depositor

David Libich

Article

Selig et al Proc Natl Acad Sci U S A. 2025 May 20;12

Insert

FLI1 (FLI1 Human)

Tags

His8

Expression

Bacterial

Mutation

deleted amino acids 1-275, 400-452, mutated C299S…

Promoter

T7

Available Since

June 9, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgCrls1-1#

Plasmid

#234765

Purpose

knockout Crls1

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Crls1 (Crls1 Mouse)

Use

Lentiviral

Available Since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgCrls1-2#

Plasmid

#234766

Purpose

knockout Crls

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Crls1 (Crls1 Mouse)

Use

Lentiviral

Available Since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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3xFLAG-DGKδ2-ΔSAMD

Plasmid

#226507

Purpose

Express N-terminal three tandem FLAG epitope tags, followed by an enterokinase cleavage site and human DGKD gene deleted SAM domain

Depositor

Chiaki Murakami, Fumio Sakane

Article

Murakami et al J Biol Chem. 2020 Mar 6;295(10):2932-294

Insert

DGKD (DGKD Human)

Tags

Three tandem FLAG epitope tag and enterokinase cl…

Expression

Mammalian

Mutation

deleted sterile alpha motif domain (deleted amino…

Promoter

CMV

Available Since

Jan. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1-FRB:GSlinker:SSD

Plasmid

#228535

Purpose

FRB protein in fusion with a bipartite SSD degron, consisting of fragments of human Skp1 and SOCS2 proteins, through a flexible glycine-serine linker.

Depositor

Roman Jerala

Article

Verbic et al ACS Synth Biol. 2024 Mar 15;13(3):792-80

Insert

FRB:GSlinker:SSD (SKP1, SOCS2 Human, Synthetic)

Expression

Mammalian

Promoter

CMV

Available Since

Jan. 3, 2025

Availability

Academic Institutions and Nonprofits only

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