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pMyc-CMV1-huTLR4mut-C1196T

Plasmid

#53526

Purpose

expression of mutant TLR4 in mammalian cells

Depositor

Linda Yu

Article

Kuo et al Cell Death Differ. 2015 Jan 30. doi: 10.

Insert

TLR4 C1196T (TLR4 Human)

Tags

Myc

Expression

Mammalian

Mutation

C1196T

Promoter

CMV

Available Since

July 21, 2014

Availability

Academic Institutions and Nonprofits only

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pMyc-CMV1-huTLR4mut-A896G

Plasmid

#53525

Purpose

expression of mutant TLR4 in mammalian cells

Depositor

Linda Yu

Article

Kuo et al Cell Death Differ. 2015 Jan 30. doi: 10.

Insert

TLR4 A896G (TLR4 Human)

Tags

Myc

Expression

Mammalian

Mutation

A896G

Promoter

CMV

Available Since

July 21, 2014

Availability

Academic Institutions and Nonprofits only

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pSLIK 3XFLAG-MKK7-EE-NLS hygro

Plasmid

#87780

Purpose

Inducible expression of constitutively active mutant MKK7 with a C-terminal NLS sequence

Depositor

Kevin Janes

Article

Shah et al Mol Cell Proteomics. 2017 Apr;16(4 suppl

Insert

MKK7 (Map2k7 Mouse)

Use

Lentiviral

Tags

3xFLAG and NLS

Expression

Mammalian

Available Since

April 10, 2017

Availability

Academic Institutions and Nonprofits only
Plxnb2(L)-AP-His

Plasmid

#72002

Purpose

Expresses the extracellular region of the PlexinB2 protein (ie, long), C-terminally fused to alkaline phosphatase + 6X histidine tag.

Depositor

Woj Wojtowicz

Article

Visser et al Elife. 2015 Dec 3;4. pii: e08149. doi: 1

Insert

Plxnb2 (Plxnb2 Mouse)

Tags

AP-His

Expression

Mammalian

Promoter

CMV

Available Since

Jan. 22, 2016

Availability

Academic Institutions and Nonprofits only

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pGEX-BAIAP2 S366A

Plasmid

#31676

Depositor

Anne Brunet

Article

Banko et al Mol Cell. 2011 Dec 23;44(6):878-92. Epub

Insert

BAI1-associated protein 2 S366A (BAIAP2 Human)

Tags

GST

Expression

Bacterial

Mutation

changed Serine 366 to Alanine

Available Since

Feb. 17, 2012

Availability

Academic Institutions and Nonprofits only
integrin alpha9 W999A pcDNA1 neo

Plasmid

#13589

Depositor

Dean Sheppard

Article

Young et al Mol Biol Cell. 2001 Oct . 12(10):3214-25

Insert

integrin alpha 9 W999A (ITGA9 Human)

Expression

Mammalian

Mutation

W999A

Available Since

Jan. 8, 2007

Availability

Academic Institutions and Nonprofits only

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EGFP G protein Gamma 3(K68A,K69A,F70A,F71A) in pcDNA3.1

Plasmid

#42189

Depositor

Narasimhan Gautam

Article

O'Neill et al Proc Natl Acad Sci U S A. 2012 Dec 18;10

Insert

Gamma 3(K68A,K69A,F70A,F71A) (Gng3 Mouse)

Tags

EGFP

Expression

Mammalian

Mutation

K68A,K69A,F70A,F71A

Promoter

CMV

Available Since

March 25, 2013

Availability

Academic Institutions and Nonprofits only
EGFP G protein Gamma 3(A73L,L74I,L75S) in pcDNA3.1

Plasmid

#42190

Depositor

Narasimhan Gautam

Article

O'Neill et al Proc Natl Acad Sci U S A. 2012 Dec 18;10

Insert

G protein Gamma 3(A73L,L74I,L75S) (Gng3 Mouse)

Tags

EGFP

Expression

Mammalian

Mutation

A73L,L74I,L75S

Promoter

CMV

Available Since

March 25, 2013

Availability

Academic Institutions and Nonprofits only
pET15b His SUMO mNeon R338A PPM1H

Plasmid

#245124

Purpose

Expresses His SUMO mNeon R338A PPM1H in bacterial cells

Depositor

Suzanne Pfeffer

Article

Adhikari et al J Biol Chem. 2025 Sep 3:110679. doi: 10.

Insert

His SUMO mNeon (loop 1) R338A PPM1H (PPM1H Human)

Tags

His SUMO tagged with mNeon

Expression

Bacterial

Mutation

changed Arginine 338 to Alanine

Available Since

Feb. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pDonor RUNX3-P2A-tdTomato

Plasmid

#246655

Purpose

Donor plasmid for Crispr/Cas9 gene editing of the human RUNX3 locus

Depositor

Joriene de Nooij

Article

Malka-Gibor et al Stem Cell Reports. 2026 Jan 2:102753. do

Insert

P2A-tdTomato flanked by RUNX3 homology regions (RUNX3 Synthetic, Human)

Use

CRISPR

Expression

Mammalian

Available Since

Jan. 28, 2026

Availability

Academic Institutions and Nonprofits only

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pGuide-AVIL

Plasmid

#246656

Purpose

Guide RNA for human AVIL

Depositor

Joriene de Nooij

Article

Malka-Gibor et al Stem Cell Reports. 2026 Jan 2:102753. do

Insert

AVIL guide RNA (AVIL Human)

Use

CRISPR

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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pGuide-MAFA

Plasmid

#246658

Purpose

Guide RNA for human MAFA

Depositor

Joriene de Nooij

Article

Malka-Gibor et al Stem Cell Reports. 2026 Jan 2:102753. do

Insert

MAFA guide RNA (MAFA Human)

Use

CRISPR

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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pET15b His SUMO mNeon L66R PPM1H

Plasmid

#240064

Purpose

Expresses His SUMO mNeon (inserted in loop 1) L66R PPM1H phosphtase in bacterial cells

Depositor

Suzanne Pfeffer

Article

Adhikari et al J Biol Chem. 2025 Sep 3:110679. doi: 10.

Insert

His SUMO mNeon (loop 1) L66R PPM1H (PPM1H Human)

Expression

Bacterial

Available Since

Sept. 23, 2025

Availability

Academic Institutions and Nonprofits only

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pET15b His SUMO mNeon Δ37 PPM1H

Plasmid

#240065

Purpose

Expresses His SUMO mNeon (inserted in loop1) Δ37 PPM1H in bacterial cells

Depositor

Suzanne Pfeffer

Article

Adhikari et al J Biol Chem. 2025 Sep 3:110679. doi: 10.

Insert

His SUMO mNeon (loop 1) Δ37 PPM1H (PPM1H Human)

Expression

Bacterial

Available Since

Sept. 23, 2025

Availability

Academic Institutions and Nonprofits only

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pET28a-His6-GFP-UROD

Plasmid

#236741

Purpose

Protein overexpression of eGFP-human uroporphyrinogen decarboxylase

Depositor

Christina Woo

Article

Lloyd et al Cell Chem Biol. 2025 Aug 5:S2451-9456(25

Insert

eGFP-Uroporphyrinogen decarboxylase human (UROD Synthetic, Human)

Tags

His6 and eGFP

Expression

Bacterial

Available Since

Aug. 11, 2025

Availability

Academic Institutions and Nonprofits only

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pET28a-His6-GFP-UROD-N367A

Plasmid

#236742

Purpose

Protein overexpression of eGFP-human uroporphyrinogen decarboxylase N367A

Depositor

Christina Woo

Article

Lloyd et al Cell Chem Biol. 2025 Aug 5:S2451-9456(25

Insert

eGFP-Uroporphyrinogen decarboxylase human N367A (UROD Synthetic, Human)

Tags

His6 and eGFP

Expression

Bacterial

Mutation

N367A

Available Since

Aug. 11, 2025

Availability

Academic Institutions and Nonprofits only

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pYTRW27K_7Ti1

Plasmid

#177294

Purpose

genomic integration of genes (inserted in I-SceI-site) via rrn-interposon/SacB with TcR and LacZ

Depositor

Karl-Erich Jaeger

Article

Weihmann et al FEMS Microbes. 2022 Dec 19;4:xtac030. do

Insert

PsacB-sacB

Use

Synthetic Biology; Yeast expression, rrn genomic …

Expression

Bacterial

Available Since

Aug. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-mGFAP(ABC1D)-2pabPAC

Plasmid

#234547

Purpose

to express the optogenetic tool 2pabPAC, which increases cAMP levels when stimulated by blue light, in astrocytes

Depositor

Hajime Hirase

Article

Vittani et al Proc Natl Acad Sci U S A. 2025 Jul 8;122

Insert

2pabPAC

Use

AAV

Mutation

None

Promoter

mGFAP(ABC1D)

Available Since

July 15, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3-Lyso-ExRai-CKAR2

Plasmid

#236100

Purpose

Enhanced excitation-ratiometric biosensor for monitoring Protein Kinase C activity in living cells, targeted to lysosome surface.

Depositor

Jin Zhang

Article

Su et al Nat Chem Biol. 2024 Oct 11. doi: 10.1038

Insert

LAMP1-ExRai-CKAR2 (LAMP1 Synthetic, Human)

Tags

Full-length LAMP1

Expression

Mammalian

Promoter

CMV

Available Since

June 3, 2025

Availability

Academic Institutions and Nonprofits only

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MZB035

Plasmid

#217834

Purpose

Bacterial expression of human AP3D1 (1-617) and AP3S1 AP-3 core hemicomplex

Depositor

Richard Baker

Article

Begley et al Proc Natl Acad Sci U S A. 2024 Dec 24;12

Inserts

AP3D1 (AP3D1 Human)
AP3S1 (AP3S1 Human)

Tags

GST

Expression

Bacterial

Mutation

Removed residues 618-1153 from AP3D1

Available Since

May 14, 2025

Availability

Academic Institutions and Nonprofits only

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