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Showing: 1201 - 1250 of 1461 results

  1. pLPC-S22AProgerin-CS

    Plasmid
    #69063
    Purpose
    encodes a Progerin mutant with serine 22 mutated to an alanine and with a substitution of cysteine in CaaX-motif by a serine
    Depositor
    Gerardo Ferbeyre
    Article
    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d
    Insert
    Progerin (LMNA Human)
    Use
    Retroviral
    Tags
    Expression
    Mammalian
    Mutation
    Progerin with serine 22 mutated to alanine and wi…
    Promoter
    CMV
    Available since
    Dec. 17, 2015
    Availability
    Academic Institutions and Nonprofits only

  16. pICE-HA-Ku70-siR-Mut6E

    Plasmid
    #82330
    Purpose
    Plasmid for constitutive or doxy-inducible expression of mutant human Ku70 unable to bind DNA and resistant to siRNA. Confers resistance to puro. Use T-REx cells for doxycycline-inducible expression.
    Depositor
    Sébastien Britton, Patrick Calsou
    Article
    Lamaa et al EMBO Rep. 2016 Apr;17(4):508-18. doi: 10
    Insert
    Ku70 (XRCC6 Human)
    Use
    Tags
    HA
    Expression
    Mammalian
    Mutation
    Mut6E corresponding to K282E K287E T300E K331E K3…
    Promoter
    CMV-tet
    Available since
    Sept. 13, 2016
    Availability
    Academic Institutions and Nonprofits only
    82330-plasmid-map-sequence-id-155730

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  37. Donor-CD55-NeoR

    Plasmid
    #153551
    Purpose
    Used as a donor vector for the targeted knock-in of a CD55 mutation. This plasmid carries a neomycin resistance gene cassette
    Depositor
    Hiroyuki Konishi
    Article
    Hyodo et al Cell Rep. 2020 Jan 28;30(4):1195-1207.e7
    Insert
    mutant CD55 (a 1415-bp fragment from intron 3, exon 4 and intron 4, with a 1-bp mutation in exon 4), divided into 5' and 3' arms
    Use
    AAV and Cre/Lox; Donor plasmid/targeting vector
    Tags
    N/A
    Expression
    Mutation
    a 1-bp mutation in exon 4
    Promoter
    No promoter
    Available since
    March 8, 2021
    Availability
    Academic Institutions and Nonprofits only
    153551-plasmid-map-sequence-id-326384

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  38. Donor-PIGA-NeoR

    Plasmid
    #153549
    Purpose
    Used as a donor vector for the targeted knock-in of a PIGA mutation. This plasmid carries a neomycin resistance gene cassette
    Depositor
    Hiroyuki Konishi
    Article
    Hyodo et al Cell Rep. 2020 Jan 28;30(4):1195-1207.e7
    Insert
    mutant PIGA (a 1,991-bp fragment from intron 5 and exon 6 with a 3-bp mutation in exon 6), divided into 5' and 3' arms
    Use
    AAV and Cre/Lox; Donor plasmid/targeting vector
    Tags
    N/A
    Expression
    Mutation
    a 3-bp mutation in exon 6
    Promoter
    No promoter
    Available since
    Dec. 11, 2020
    Availability
    Academic Institutions and Nonprofits only
    153549-plasmid-map-sequence-id-319273

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  40. pSG5 Large T delta 434-444

    Plasmid
    #9054
    Depositor
    William Hahn
    Insert
    large T antigen d434-444 (SV40gp6 simian virus)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    deletion in part of the bipartite p53 binding dom…
    Promoter
    Available since
    Nov. 3, 2005
    Availability
    Academic Institutions and Nonprofits only

  41. pLenti CMV GSE T329A Hygro (w189-4)

    Plasmid
    #22255
    Depositor
    Eric Campeau
    Insert
    Genetic suppressor element #22, T329A
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Threonine 329 is mutated to Alanine (p53 nomencat…
    Promoter
    Available since
    Dec. 15, 2009
    Availability
    Academic Institutions and Nonprofits only
    22255-plasmid-map-sequence-id-10195

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  49. pBABEneo mt T Ag

    Plasmid
    #133713
    Purpose
    Large T antigen mutant form in pBABEneo vector for mammalian expression.
    Depositor
    James A. DeCaprio
    Insert
    SV40gp6 (SV40gp6 SV40)
    Use
    Retroviral
    Tags
    Expression
    Mutation
    aa 1-354 of T antigen (including aa 1-130); no p5…
    Promoter
    Available since
    March 31, 2020
    Availability
    Academic Institutions and Nonprofits only
    133713-plasmid-map-sequence-id-276425

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  50. pcDNA3-HA2-PARC

    Plasmid
    #20937
    Depositor
    Yue Xiong
    Insert
    p53-associated parkin-like cytoplasmic protein (CUL9 Human)
    Use
    Tags
    HA2
    Expression
    Mammalian
    Mutation
    S1049N, C1076R, R2389L
    Promoter
    Available since
    April 14, 2009
    Availability
    Academic Institutions and Nonprofits only
    20937-plasmid-map-sequence-id-218362

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Showing: 1201 - 1250 of 1461 results