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pGEX-chCARex

Plasmid

#87233

Purpose

bacterial expression of GST-CAR extracellular domain

Depositor

Fritz Rathjen

Article

Patzke et al J Neurosci. 2010 Feb 24;30(8):2897-910.

Insert

CXADR (CXADR Chicken)

Tags

GST

Expression

Bacterial

Promoter

tac

Available Since

Feb. 28, 2017

Availability

Academic Institutions and Nonprofits only

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KL301: pMAGIC (R4-R3) NLS-(SrfI/PmeI)-NLS-p300core

Plasmid

#121839

Purpose

pMAGIC R4-R3 entry plasmid, contains 2x NLS/p300core scaffold enabling addition of dCas9 mutants into pMAGIC. dCas9 can be inserted via unique SrfI/PmeI restriction sites

Depositor

Christopher Newgard

Article

Haldeman et al Nucleic Acids Res. 2018 Dec 27. pii: 526

Type

Empty backbone

Use

Synthetic Biology; Pmagic gateway entry plasmid

Available Since

June 27, 2019

Availability

Academic Institutions and Nonprofits only

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pEMS1958

Plasmid

#82569

Purpose

High copy number plasmid containing PR2/3:Con MiniPromoter insert.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

PRS2/3:Con

Use

Pleiades promoter project [sic, pleaides plieades]

Available Since

Sept. 14, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA5 FRT TO myc Separase delta 55/S1126A

Plasmid

#59825

Purpose

Allows the integration of myc Separase delta 55/S1126A in the genome and Tet-inducible expression.

Depositor

Stephen Taylor

Article

Holland et al J Biol Chem. 2007 Aug 24;282(34):24623-3

Insert

Separase (ESPL1 Human)

Tags

Myc

Expression

Mammalian

Mutation

delta 55/S1126A

Promoter

hybrid human cytomegalovirus (CMV)/TetO2 promoter

Available Since

May 12, 2015

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(+)mGAT1-577-CFP-578CT

Plasmid

#41682

Depositor

Henry Lester

Article

Moss et al J Gen Physiol. 2009 Dec;134(6):489-521.

Insert

Mus musculus GABA transporter 1 (Slc6a1 Mouse, Synthetic)

Tags

CFP

Expression

Mammalian

Mutation

“Monomerizing” CFP A206K mutation; CFP inserted d…

Promoter

CMV

Available Since

April 27, 2016

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(+)mGAT1-577-YFP-578CT

Plasmid

#41681

Depositor

Henry Lester

Article

Moss et al J Gen Physiol. 2009 Dec;134(6):489-521.

Insert

Mus musculus GABA transporter 1 (Slc6a1 Mouse, Synthetic)

Tags

YFP

Expression

Mammalian

Mutation

“Monomerizing” YFP A206K mutation; YFP inserted d…

Promoter

CMV

Available Since

April 27, 2016

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(+)mGAT1CFP*

Plasmid

#41666

Depositor

Henry Lester

Article

Moss et al J Gen Physiol. 2009 Dec;134(6):489-521.

Insert

Mus musculus GABA transporter 1 (Slc6a1 Mouse, Synthetic)

Tags

CFP

Expression

Mammalian

Mutation

“Monomerizing” CFP A206K mutation; C-terminal hyd…

Promoter

CMV

Available Since

Jan. 30, 2013

Availability

Academic Institutions and Nonprofits only

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pEMS1978

Plasmid

#49110

Purpose

AAV plasmid with C8ORF46 (Ple251) promoter driving expression of iCre. Contains WPRE.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-Ple251-icre-WPRE

Use

AAV

Expression

Mammalian

Promoter

C8ORF46

Available Since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS2026

Plasmid

#49133

Purpose

AAV plasmid with TNNT1-B (Ple301) promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-Ple301-iCre

Use

AAV

Expression

Mammalian

Promoter

TNNT1-B

Available Since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pcDNA3-Rog

Plasmid

#24429

Depositor

Bruce Conklin

Article

Scearce-Levie et al BMC Biol. 2005 Feb 11;3:3. doi: 10.1186/

Insert

RASSL (OPRK1 Human)

Tags

FLAG and GFP

Expression

Mammalian

Mutation

mutations in extracellular loops 2 (see comments …

Available Since

June 16, 2010

Availability

Academic Institutions and Nonprofits only

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SIN-cPPT-G1B3-Gateway-WPRE-miR124T

Plasmid

#245070

Purpose

Gateway cloning with miRNA-124 target sequence to repress transgene expression in neurons

Depositor

Nicole Déglon

Article

Merienne et al Cell Rep. 2017 Sep 19;20(12):2980-2991.

Insert

Gateway

Use

Lentiviral

Expression

Mammalian

Promoter

human GFAP fragments

Available Since

March 19, 2026

Availability

Academic Institutions and Nonprofits only

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pTA-M+

Plasmid

#249818

Purpose

Expresses Mycobacterium tuberculosis topoisomerase I under the control of the Tet promoter in mycobacteria

Depositor

Yuk-Ching Tse-Dinh

Article

Sandhaus et al Antimicrob Agents Chemother. 2016 Jun 20

Insert

Mycobacterium tuberculosis topoisomerase I (topA Mycobacterium tuberculosis)

Tags

6xHis

Expression

Bacterial

Promoter

Tet

Available Since

March 9, 2026

Availability

Academic Institutions and Nonprofits only

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pET15-VraS - L114S/D242G

Plasmid

#206873

Purpose

Bacterial Expression of VraS double mutant L114S/D242G

Depositor

May Abdelaziz

Article

Cagle-White et al Arch Biochem Biophys. 2026 Feb;776:11071

Insert

VraS

Tags

6x His

Expression

Bacterial

Mutation

L114S/D242G

Available Since

Jan. 8, 2026

Availability

Academic Institutions and Nonprofits only

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SIN-cPPT-G1B3-GFP-WPRE-miR124T

Plasmid

#245069

Purpose

Fluorescent reporter gene with miRNA-124 target sequence to repress transgene expression in neurons

Depositor

Nicole Déglon

Article

Merienne et al Cell Rep. 2017 Sep 19;20(12):2980-2991.

Insert

EGFP, miR124T site

Use

Lentiviral

Expression

Mammalian

Promoter

Human G1B3 promoter

Available Since

Dec. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pLVX-EF1_-EGFR-FCRL3-140aa-Chimera-puro

Plasmid

#248151

Purpose

Lentiviral vector encoding a chimeric protein composed of the transmembrane region of FCRL3 and its full-length cytoplasmic tail, fused to the extracellular domain of EGFR.

Depositor

Silvia Monticelli

Article

Bianchi et al J Exp Med (2026) 223 (1): e20242474.

Insert

EGFR-FCRL3 (FCRL3 Human)

Use

Lentiviral

Promoter

EF1_

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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pLVX-EF1_-FCRL3-50aa-puro

Plasmid

#248153

Purpose

Lentiviral vector encoding a truncated form of human FCRL3, containing only the first 50 residues of the cytoplasmic tail.

Depositor

Silvia Monticelli

Article

Bianchi et al J Exp Med (2026) 223 (1): e20242474.

Insert

FCRL3 (FCRL3 Human)

Use

Lentiviral

Mutation

Mutagenesis to insert a stop codon at aa645 in FC…

Promoter

EF1_

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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pLVX-EF1_-FCRL3-16aa-puro

Plasmid

#248152

Purpose

Lentiviral vector encoding a truncated form of human FCRL3, containing only the first 16 residues of the cytoplasmic tail.

Depositor

Silvia Monticelli

Article

Bianchi et al J Exp Med (2026) 223 (1): e20242474.

Insert

FCRL3 (FCRL3 Human)

Use

Lentiviral

Mutation

Mutagenesis to insert a stop codon at aa611 in FC…

Promoter

EF1_

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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pLVX-EF1_-EGFR- FCRL3-50aa-Chimera-puro

Plasmid

#248150

Purpose

Lentiviral vector encoding a chimeric protein composed of the transmembrane region of FCRL3 and its truncated cytoplasmic tail (aa 595-644; first 50 residues), fused to the extracellular domain of EGFR.

Depositor

Silvia Monticelli

Article

Bianchi et al J Exp Med (2026) 223 (1): e20242474.

Insert

EGFR-FCRL3 (FCRL3 Human)

Use

Lentiviral

Promoter

EF1_

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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pLVX-EF1_-FCRL3-93aa-puro

Plasmid

#248154

Purpose

Lentiviral vector encoding a truncated form of human FCRL3, containing only the first 93 residues of the cytoplasmic tail.

Depositor

Silvia Monticelli

Article

Bianchi et al J Exp Med (2026) 223 (1): e20242474.

Insert

FCRL3 (FCRL3 Human)

Use

Lentiviral

Mutation

Mutagenesis to insert a stop codon at aa688 in FC…

Promoter

EF1_

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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pLVX-EF1_-EGFR-FCRL3-93aa-Chimera-puro

Plasmid

#248149

Purpose

Lentiviral vector encoding a chimeric protein composed of the transmembrane region of FCRL3 and its truncated cytoplasmic tail (aa 595-687; first 93 residues), fused to the extracellular domain of EGFR.

Depositor

Silvia Monticelli

Article

Bianchi et al J Exp Med (2026) 223 (1): e20242474.

Insert

EGFR-FCRL3 (FCRL3 Human)

Use

Lentiviral

Promoter

EF1_

Available Since

Dec. 12, 2025

Availability

Academic Institutions and Nonprofits only

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