12,913 results

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pBMN-MEF2D

Plasmid

#232628

Purpose

Lentiviral plasmid expressing mouse MEF2D.

Depositor

Claes Wadelius

Article

Christensen et al Eur Heart J. 2025 Apr 10:ehaf213. doi: 1

Insert

MEF2D (Mef2d Mouse)

Use

Lentiviral

Tags

HA-3xFLAG

Expression

Mammalian

Promoter

CMV

Available Since

April 11, 2025

Availability

Academic Institutions and Nonprofits only

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pCpep-E1GFP

Plasmid

#233884

Purpose

Expression of a pH sensitive variant of EGFP inserted in the C-peptide of insulin for pH measurement in insulin secretory granules

Depositor

Francesco Cardarelli

Article

De Lorenzi et al Commun Biol. 2025 Feb 25;8(1):304. doi:

Insert

Proinsulin-E1GFP (Ins2 Mouse)

Expression

Mammalian

Mutation

Inserted E1GFP into C-peptide of mouse Ins2 codin…

Promoter

CMVF

Available Since

April 9, 2025

Availability

Academic Institutions and Nonprofits only

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pGL3-Cyr61-rDMR

Plasmid

#235692

Purpose

Measure the activity of the reduced differentially methylated region (rDMR) of Cyr61 with luciferase assay

Depositor

Duojia Pan

Article

Wu et al Nat Genet. 2022 Aug;54(8):1202-1213. doi

Insert

Cyr61 (Ccn1 Mouse)

Use

Luciferase

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

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pGL3-Cyr61-rDMRdeltaTEAD

Plasmid

#235693

Purpose

Measure the activity of the reduced differentially methylated region (rDMR) of Cyr61 lacking Tead-binding motif with luciferase assay

Depositor

Duojia Pan

Article

Wu et al Nat Genet. 2022 Aug;54(8):1202-1213. doi

Insert

Cyr61 (Ccn1 Mouse)

Use

Luciferase

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

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pGL3-Ctgf-rDMR

Plasmid

#235696

Purpose

Measure the activity of the reduced differentially methylated region (rDMR) of Ctgf with luciferase assay

Depositor

Duojia Pan

Article

Wu et al Nat Genet. 2022 Aug;54(8):1202-1213. doi

Insert

Ctgf (Ccn2 Mouse)

Use

Luciferase

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

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pGL3-Ctgf-rDMRdeltaTEAD

Plasmid

#235697

Purpose

Measure the activity of the reduced differentially methylated region (rDMR) of Ctgf lacking Tead-binding motif with luciferase assay

Depositor

Duojia Pan

Article

Wu et al Nat Genet. 2022 Aug;54(8):1202-1213. doi

Insert

Ctgf (Ccn2 Mouse)

Use

Luciferase

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

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pGL3-Myc-rDMR

Plasmid

#235694

Purpose

Measure the activity of the reduced differentially methylated region (rDMR) of Myc with luciferase assay

Depositor

Duojia Pan

Article

Wu et al Nat Genet. 2022 Aug;54(8):1202-1213. doi

Insert

Myc (Myc Mouse)

Use

Luciferase

Available Since

April 3, 2025

Availability

Academic Institutions and Nonprofits only

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PX459_L31_CRISPR_downstream_sgRNA

Plasmid

#235610

Purpose

Encodes CRISPR gRNA for cleaving downstream of insertion site at C terminus of mouse Rpl31

Depositor

Maria Barna

Article

Zhang et al Science. 2025 Mar 7;387(6738):eadn2623.

Insert

Rpl31 C-terminus downstream sgRNA

Use

CRISPR

Available Since

April 2, 2025

Availability

Academic Institutions and Nonprofits only

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PX459_L31_CRISPR_upstream_sgRNA

Plasmid

#235609

Purpose

Encodes CRISPR gRNA for cleaving upstream of insertion site at C terminus of mouse Rpl31

Depositor

Maria Barna

Article

Zhang et al Science. 2025 Mar 7;387(6738):eadn2623.

Insert

Rpl31 C-terminus upstream sgRNA

Use

CRISPR

Available Since

April 2, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1-mSyncytin-A

Plasmid

#182454

Purpose

mouse syncytin-A

Depositor

Masaharu Somiya

Insert

syncytin-A (Syna Mouse)

Expression

Mammalian

Promoter

CMV

Available Since

April 1, 2025

Availability

Academic Institutions and Nonprofits only

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pCARGO-RMCE-Airn

Plasmid

#233266

Purpose

CARGO plasmid containing ~90kb dox-inducible Airn transgene

Depositor

Mauro Calabrese

Article

Trotman et al Mol Cell. 2025 Mar 20;85(6):1117-1133.e1

Insert

Airn (Airn Mouse)

Expression

Mammalian

Available Since

March 28, 2025

Availability

Academic Institutions and Nonprofits only

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p5E-Dll4-F2-E1B-B-Globin (JDW 1366)

Plasmid

#229843

Purpose

A gateway compatible 5' entry clone containing the murine Dll4 F2 arterial specific enhancer upstream of a minimal E1b promoter and intron for arterial and endocardial expression.

Depositor

Joshua Wythe

Article

Gillespie WB et al Development. 2025 Nov 15;152(22):dev2043

Insert

Dll4-F2 (exon3)

Use

Gateway entry clone

Available Since

March 28, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgCrls1-1#

Plasmid

#234765

Purpose

knockout Crls1

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Crls1 (Crls1 Mouse)

Use

Lentiviral

Available Since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgCrls1-2#

Plasmid

#234766

Purpose

knockout Crls

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Crls1 (Crls1 Mouse)

Use

Lentiviral

Available Since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgPlscr3-2#

Plasmid

#234772

Purpose

knockout Plscr3

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Plscr3 (Plscr3 Mouse)

Use

Lentiviral

Available Since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgPlscr3-1#

Plasmid

#234767

Purpose

knockout Plscr3

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Plscr3 (Plscr3 Mouse)

Use

Lentiviral

Available Since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-mEtfdh-AAA4

Plasmid

#232316

Purpose

Expression of mouse mutant Etfdh (AAA4)

Depositor

Ivan Topisirovic

Article

Papadopoli et al bioRxiv 2024.10.25.620155

Insert

Etfdh (Etfdh Mouse)

Use

Lentiviral

Mutation

PAM Sequence Mutations: (G36C; T39C, C42T; C72T, …

Available Since

March 26, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti-mEtfdh

Plasmid

#232314

Purpose

Expression of mouse mutant Etfdh

Depositor

Ivan Topisirovic

Article

Papadopoli et al bioRxiv 2024.10.25.620155

Insert

Etfdh (Etfdh Mouse)

Use

Lentiviral

Mutation

PAM Sequence Mutations: (G36C, T39C, C42T, C72T, …

Available Since

March 26, 2025

Availability

Academic Institutions and Nonprofits only

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KL095 - pTRE3G-Flag-Halo-CTCF_ZF1_mutant-BGHpA-CAGGS-rtta3G-rbgpA-Frt-PGK-EM7-PuroR-bpA-Frt TIGRE donor

Plasmid

#232931

Purpose

Vector to introduce a constitutive rtta3G cassette and a DOX-inducible Flag-Halo-mCTCF ZF1 mutant, targeting the mouse TIGRE acceptor locus. Use with Addgene #92144 sgRNA. Use puromycin selection.

Depositor

Danny Reinberg

Article

Lucero et al bioRxiv, March 19, 2025

Insert

Flag-Halo-CTCF ZF1 deletion mutant

Use

Mouse Targeting

Expression

Mammalian

Mutation

Deleted amino acids 264-277

Available Since

March 26, 2025

Availability

Academic Institutions and Nonprofits only

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AAV-U6/TO-shEsr1-CMV-TetR-eGFP

Plasmid

#233298

Purpose

DOX-inducible U6 driven shRNA against mouse Esr1

Depositor

Dayu Lin

Article

Golden et al bioRxiv [Preprint]. 2024 Sep 25:2023.12.

Insert

Esr1 shRNA (Esr1 Mouse)

Use

AAV

Expression

Mammalian

Promoter

U6

Available Since

March 24, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo PTEN sgRNA5

Plasmid

#233246

Purpose

Knock out of murine PTEN

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

PTEN (Pten Mouse)

Use

Lentiviral

Available Since

March 20, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-EF1a-mHFE(H67D)-IRES-GFP-WPRE-pA

Plasmid

#233040

Purpose

To express mouse homeostatic iron regulator (HFE)(H67D) from an EF1a promoter. It also encodes GFP after an IRES sequence

Depositor

Jonathan Ploski

Insert

mouse homeostatic iron regulator with H67D mutation (Hfe Mouse)

Use

AAV

Tags

GFP

Mutation

H67D

Available Since

March 20, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo sgITGA5_5

Plasmid

#233253

Purpose

Knock out of murine ITGA5

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

ITGA5 (Itga5 Mouse)

Use

Lentiviral

Available Since

March 19, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo sgITGA5_4

Plasmid

#233252

Purpose

Knock out of murine ITGA5

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

ITGA5 (Itga5 Mouse)

Use

Lentiviral

Available Since

March 19, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR V2 Neo sgITGA5_1

Plasmid

#233251

Purpose

Knock out of murine ITGA5

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

ITGA5 (Itga5 Mouse)

Use

Lentiviral

Available Since

March 19, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 Neo sgITGB1_3

Plasmid

#233250

Purpose

Knock out of murine ITGB1

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

ITGB1 (Itgb1 Mouse)

Use

Lentiviral

Available Since

March 19, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pLentiCRISPR V2 Neo sgITGB1_2

Plasmid

#233249

Purpose

Knock out of murine ITGB1

Depositor

David Bryant

Article

Nikolatou et al EMBO J. 2023 Sep 18;42(18):e113987. doi:

Insert

ITGB1 (Itgb1 Mouse)

Use

Lentiviral

Available Since

March 19, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE2-TetO-Sox2-HMG

Plasmid

#231532

Purpose

Expresses mouse Sox2 HMG in mammalian cells, for lentivirus generation

Depositor

Ralf Jauch

Article

Gao et al Nat Commun. 2024 Nov 14;15(1):9868. doi:

Insert

mSox2 HMG

Use

Lentiviral

Available Since

March 14, 2025

Availability

Academic Institutions and Nonprofits only

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pWPI-Glis3M412

Plasmid

#216854

Purpose

This plasmid is for the production of lentiviral vectors expressing an active form of Glis3 together with GFP.

Depositor

Patrick Salmon

Insert

Glis3 (Glis3 Mouse)

Use

Lentiviral

Mutation

N-terminal deletion removing repressor domains

Promoter

EF1 alpha

Available Since

March 14, 2025

Availability

Academic Institutions and Nonprofits only

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AAV-Grik1-GFP

Plasmid

#233645

Purpose

Expresses GFP in OFF cone bipolar cells

Depositor

Connie Cepko

Article

Avilés et al J Gen Physiol. 2025 Mar 3;157(2):e202413

Insert

Grik1 promoter (Grik1 Mouse)

Use

AAV

Available Since

March 13, 2025

Availability

Academic Institutions and Nonprofits only

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