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pCEP4-myc-CXCR4-W161Y

Plasmid

#98951

Purpose

Mammalian expression plasmid for N-terminal myc-tagged human CXCR4 mutant W161Y

Depositor

Erik Procko

Article

Heredia et al J Immunol. 2018 Apr 20. pii: jimmunol.18

Insert

CXCR4 (CXCR4 Human)

Use

Tags

Signal/leader sequence from Influenza A virus HA …

Expression

Mammalian

Mutation

W161Y: enhanced CXCL12 binding and signaling

Promoter

CMV

Available since

April 24, 2018

Availability

Academic Institutions and Nonprofits only

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pCEP4-myc-CXCR4-W161H

Plasmid

#98952

Purpose

Mammalian expression plasmid for N-terminal myc-tagged human CXCR4 mutant W161H

Depositor

Erik Procko

Article

Heredia et al J Immunol. 2018 Apr 20. pii: jimmunol.18

Insert

CXCR4 (CXCR4 Human)

Use

Tags

Signal/leader sequence from Influenza A virus HA …

Expression

Mammalian

Mutation

W161H: enhanced CXCL12 binding and signaling

Promoter

CMV

Available since

April 24, 2018

Availability

Academic Institutions and Nonprofits only

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pCEP4-myc-CXCR4-H79Q

Plasmid

#98953

Purpose

Mammalian expression plasmid for N-terminal myc-tagged human CXCR4 mutant H79Q

Depositor

Erik Procko

Article

Heredia et al J Immunol. 2018 Apr 20. pii: jimmunol.18

Insert

CXCR4 (CXCR4 Human)

Use

Tags

Signal/leader sequence from Influenza A virus HA …

Expression

Mammalian

Mutation

H79Q: enhanced CXCL12 binding and signaling

Promoter

CMV

Available since

April 24, 2018

Availability

Academic Institutions and Nonprofits only

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CXCR4-Tango

Plasmid

#66262

Purpose

Expression of G protein-coupled receptors for PRESTO-Tango: parallel receptorome expression and screening via transcriptional output, with transcriptional activation following arrestin translocation

Depositor

Bryan Roth

Article

Kroeze et al Nat Struct Mol Biol. 2015 May;22(5):362-

Insert

CXCR4 (CXCR4 Human)

Use

Tags

FLAG

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Sept. 15, 2015

Availability

Academic Institutions and Nonprofits only

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pU6-sgCXCR4-2

Plasmid

#46917

Purpose

Human pSico-based U6 vector containing murine U6 promoter and sgRNA targeting endogenous CXCR4 gene

Depositor

Jonathan Weissman, Stanley Qi

Article

Gilbert et al Cell. 2013 Jul 9. pii: S0092-8674(13)008

Inserts

sgCXCR4 -2 (CXCR4 Human)
Puromycin resistance and mCherry

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

CMV and U6

Available since

Oct. 1, 2013

Availability

Academic Institutions and Nonprofits only

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pKLV-EF1a-mCherryCXCR4-W

Plasmid

#200102

Purpose

Lentiviral vector expressing mCherry fused with CXCR4 cDNA at the C-terminus

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4 (CXCR4 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

silent mutations (c.180C>T, 438G>A, 495C>…

Promoter

Available since

Jan. 17, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(CXCR4-E1(15))-PGKpuro2ABFP-W

Plasmid

#200478

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E1

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E1(15) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

April 1, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(CXCR4-E2(38))-PGKpuro2ABFP-W

Plasmid

#200481

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E2

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E2(38) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

April 1, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(CXCR4-E3(48))-PGKpuro2ABFP-W

Plasmid

#200483

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E3

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E3(48) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 24, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(CXCR4(12))-PGKpuro2ABFP-W

Plasmid

#200460

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4(12) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 18, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(CXCR4(16))-PGKpuro2ABFP-W

Plasmid

#200461

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4(16) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 17, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(CXCR4-E4(56))-PGKpuro2ABFP-W

Plasmid

#200484

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E4

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E4(56) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 10, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(CXCR4-SE(95))-PGKpuro2ABFP-W

Plasmid

#200476

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-SE

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-SE(95) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(CXCR4-E4(59))-PGKpuro2AmCherry-W

Plasmid

#210615

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E4

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E4(59) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pKLV2-U6gRNA5(CXCR4-E4(56))-PGKpuro2AmCherry-W

Plasmid

#210614

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E4

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E4(56) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pKLV2-U6gRNA5(CXCR4-E3(45))-PGKpuro2ABFP-W

Plasmid

#200482

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E3

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E3(45) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pKLV2-U6gRNA5(CXCR4-E1(16))-PGKpuro2ABFP-W

Plasmid

#200479

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E1

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E1(16) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pKLV2-U6gRNA5(CXCR4-E4(59))-PGKpuro2ABFP-W

Plasmid

#200485

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E4

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E4(59) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 8, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pKLV2-U6gRNA5(CXCR4-E2(37))-PGKpuro2ABFP-W

Plasmid

#200480

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-E2

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-E2(37) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 5, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pKLV2-U6gRNA5(CXCR4-SE(96))-PGKpuro2ABFP-W

Plasmid

#200477

Purpose

Lentiviral vector expressing gRNA targeting human CXCR4-SE

Depositor

Kosuke Yusa

Article

Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

Insert

CXCR4-SE(96) (CXCR4 Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Jan. 5, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge

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