We narrowed to 2,433 results for: PRK

Showing: 2281 - 2320 of 2433 results

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MAPK11 gRNA (BRDN0001147839)

Plasmid

#77484

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK11

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK11 (MAPK11 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP3K9 gRNA (BRDN0001148079)

Plasmid

#77307

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP3K9

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP3K9 (MAP3K9 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP3K9 gRNA (BRDN0001145380)

Plasmid

#77308

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP3K9

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP3K9 (MAP3K9 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP3K9 gRNA (BRDN0001145934)

Plasmid

#77310

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP3K9

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP3K9 (MAP3K9 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP2K5 gRNA (BRDN0001147345)

Plasmid

#77263

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP2K5

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP2K5 (MAP2K5 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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MAP2K5 gRNA (BRDN0001147402)

Plasmid

#77264

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP2K5

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP2K5 (MAP2K5 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAP2K5 gRNA (BRDN0001147422)

Plasmid

#77265

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP2K5

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP2K5 (MAP2K5 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CIB1 gRNA (BRDN0001147177)

Plasmid

#76949

Purpose

3rd generation lentiviral gRNA plasmid targeting human CIB1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CIB1 (CIB1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
CIB1 gRNA (BRDN0001147329)

Plasmid

#76950

Purpose

3rd generation lentiviral gRNA plasmid targeting human CIB1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CIB1 (CIB1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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CIB1 gRNA (BRDN0001147051)

Plasmid

#76951

Purpose

3rd generation lentiviral gRNA plasmid targeting human CIB1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CIB1 (CIB1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAPK7 gRNA (BRDN0001146003)

Plasmid

#76897

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK7

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK7 (MAPK7 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAPK6 gRNA (BRDN0001148999)

Plasmid

#76396

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK6

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK6 (MAPK6 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAPK6 gRNA (BRDN0001146144)

Plasmid

#76397

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK6

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK6 (MAPK6 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAPK6 gRNA (BRDN0001149260)

Plasmid

#76398

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK6

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK6 (MAPK6 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAPK6 gRNA (BRDN0001146542)

Plasmid

#76399

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK6

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK6 (MAPK6 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
LMTK2 gRNA (BRDN0001145198)

Plasmid

#76173

Purpose

3rd generation lentiviral gRNA plasmid targeting human LMTK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

LMTK2 (LMTK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
LMTK2 gRNA (BRDN0001145764)

Plasmid

#76174

Purpose

3rd generation lentiviral gRNA plasmid targeting human LMTK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

LMTK2 (LMTK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
LMTK2 gRNA (BRDN0001148094)

Plasmid

#76175

Purpose

3rd generation lentiviral gRNA plasmid targeting human LMTK2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

LMTK2 (LMTK2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAP2K6 gRNA (BRDN0001145878)

Plasmid

#76039

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP2K6

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP2K6 (MAP2K6 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAP2K6 gRNA (BRDN0001145312)

Plasmid

#76040

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP2K6

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP2K6 (MAP2K6 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAP2K6 gRNA (BRDN0001147036)

Plasmid

#76041

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAP2K6

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAP2K6 (MAP2K6 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAPK10 gRNA (BRDN0001146535)

Plasmid

#75982

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK10

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK10 (MAPK10 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
MAPK10 gRNA (BRDN0001148098)

Plasmid

#75983

Purpose

3rd generation lentiviral gRNA plasmid targeting human MAPK10

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

MAPK10 (MAPK10 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

Enlarge
pLX311-GFP-MEKDD

Plasmid

#194882

Purpose

Expression of dominant negative MEK1

Depositor

Sefi Rosenbluh

Article

Tuano et al Genome Biol. 2023 Mar 29;24(1):59. doi:

Insert

MEKDD (MAP2K1 Human)

Use

Lentiviral

Expression

Mammalian

Mutation

S218D, S222D

Promoter

E1Fa

Available Since

March 31, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
RMCE halo-flag DNA-PKcs

Plasmid

#233918

Purpose

Low copy number provides expression of human DNA-PKcs with an N-terminal halo-flag tag.

Depositor

Katheryn Meek

Article

Buehl et al Mol Cell. 2023 Mar 2;83(5):698-714.e4. d

Insert

human DNA-PKcs (PRKDC Human)

Tags

flag-halo

Expression

Mammalian

Available Since

May 12, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
RMCE K>R DNA-PKcs

Plasmid

#233917

Purpose

Low copy number provides expression of human DNA-PKcs with a single K>R substitution that ablates kinase activity.

Depositor

Katheryn Meek

Article

Buehl et al Mol Cell. 2023 Mar 2;83(5):698-714.e4. d

Insert

human DNA-PKcs kinase inactive mutant K3753>R (PRKDC Human)

Expression

Mammalian

Mutation

K3753R

Available Since

May 12, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
RMCE wild type DNA-PKcs

Plasmid

#233911

Purpose

Low copy number provides expression of human DNA-PKcs

Depositor

Katheryn Meek

Article

Buehl et al Mol Cell. 2023 Mar 2;83(5):698-714.e4. d

Insert

dna-pkcs cDNA (PRKDC Human)

Expression

Mammalian

Available Since

April 9, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pDONR223_MAP2K1_WT

Plasmid

#81920

Purpose

Gateway Donor vector containing MAP2K1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

MAP2K1 (MAP2K1 Human)

Use

Gateway entry vector

Mutation

I310N

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
pDONR223_MAP2K1_p.P124S

Plasmid

#81703

Purpose

Gateway Donor vector containing MAP2K1, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

MAP2K1 (MAP2K1 Human)

Use

Gateway entry vector

Mutation

P124S; I310N

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
pBabe-Puro-Myr-Flag-AKT1

Plasmid

#15294

Depositor

William Hahn

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

AKT1 (AKT1 Human)

Use

Retroviral

Tags

Myr-Flag

Expression

Mammalian

Available Since

July 12, 2007

Availability

Academic Institutions and Nonprofits only

Enlarge
pInducer-myc-ERK1-R84S/S170D

Plasmid

#213593

Purpose

Doxycycline inducible expression of myc-tagged ERK1-R84S/S170D cDNA in mammilian cells

Depositor

Channing Der

Article

Klomp et al Science. 2024 Jun 7;384(6700):eadk0850.

Insert

MAPK3 (MAPK3 Human)

Use

Lentiviral

Tags

MYC

Expression

Mammalian

Mutation

R84S, S170D

Available Since

Aug. 23, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
MEK1 (S218D,S222D)-pcw107

Plasmid

#64604

Purpose

when used to produce lentivirus, express physiological levels of insert

Depositor

David Sabatini, Kris Wood

Article

Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

Insert

MAP2K1 (MAP2K1 Human)

Use

Lentiviral

Mutation

S218D, S222D

Promoter

PGK

Available Since

June 18, 2015

Availability

Academic Institutions and Nonprofits only

Enlarge
AKAP1-hLOV-TEVcs-GAL4bd-VP64-V5

Plasmid

#170995

Purpose

HiLITR transcription factor with AKAP1 N-terminal tmd targeting sequence (mitochondria)

Depositor

Alice Ting

Article

Coukos et al eLife. 2021 Aug 20;10. pii: 69142. doi:

Insert

AKAP1(tmd)-NNES-hLOV-TEVcs(ENLYFQ/M)-GAL4bd-VP64-V5 (AKAP1 Synthetic)

Use

Lentiviral and Synthetic Biology

Tags

V5

Expression

Mammalian

Promoter

Ef1-alpha

Available Since

Aug. 19, 2021

Availability

Academic Institutions and Nonprofits only

Enlarge
pDONR223-WNK1

Plasmid

#23670

Depositor

William Hahn, David Root

Article

Johannessen et al Nature. 2010 Dec 16;468(7326):968-72. do

Insert

WNK1 (WNK1 Human)

Use

Gateway donor vector

Mutation

G4C

Available Since

July 30, 2010

Availability

Academic Institutions and Nonprofits only
myr-FLAG-AKT1-pcw107

Plasmid

#64606

Purpose

when used to produce lentivirus, express physiological levels of insert

Depositor

David Sabatini, Kris Wood

Article

Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

Insert

AKT1 (AKT1 Human)

Use

Lentiviral

Tags

FLAG and myristoylated

Promoter

PGK

Available Since

May 12, 2015

Availability

Academic Institutions and Nonprofits only
pcDNA3-MKK1

Plasmid

#107973

Purpose

expression of MAP Kinase Kinase

Depositor

Edwin Krebs

Article

Seger et al J Biol Chem. 1994 Oct 14;269(41):25699-7

Insert

MKK1 (MAP2K1 Human)

Expression

Mammalian

Mutation

See depositor comments below.

Promoter

CMV

Available Since

Feb. 20, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pDONR223_MAPK7_WT

Plasmid

#82925

Purpose

Gateway Donor vector containing MAPK7, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, Matthew Meyerson, David Root

Article

Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

Insert

NM_002749.3 (MAPK7 Human)

Use

Gateway entry vector

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
pcDNA3-MKK1K97A

Plasmid

#107974

Purpose

expression of a dominant negative MAP Kinase Kinase

Depositor

Edwin Krebs

Article

Seger et al J Biol Chem. 1994 Oct 14;269(41):25699-7

Insert

MKK1 K97A (MAP2K1 Human)

Expression

Mammalian

Mutation

dominant negative; see Depositor Comments below

Promoter

CMV

Available Since

Jan. 7, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pBabe-Neo-Myr-Flag-AKT1

Plasmid

#15266

Depositor

William Hahn

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

AKT1 (AKT1 Human)

Use

Retroviral

Tags

Myr-Flag

Expression

Mammalian

Available Since

July 12, 2007

Availability

Academic Institutions and Nonprofits only
pInducer-myc-ERK1-R84S

Plasmid

#213591

Purpose

Doxycycline inducible expression of myc-tagged ERK1-R84S cDNA in mammilian cells

Depositor

Channing Der

Article

Klomp et al Science. 2024 Jun 7;384(6700):eadk0850.

Insert

MAPK3 (MAPK3 Human)

Use

Lentiviral

Tags

MYC

Expression

Mammalian

Mutation

R84S

Available Since

Aug. 23, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge

Showing: 2281 - 2320 of 2433 results

Results per page:

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We narrowed to 2,433 results for: PRK