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We narrowed to 1,373 results for: tox

Showing: 1141 - 1160 of 1373 results

  2. pLV-RnSyt1-sgRNA2-dCas9-KRAB-TagBFP2 (identifier AAAA-0246)

    Plasmid
    #202555
    Purpose
    Synaptotagmin-1 sgRNA2 with TagBFP2
    Depositor
    Frederic Meunier
    Article
    Joensuu et al EMBO J. 2023 Jul 3;42(13):e112095. doi:
    Insert
    CRISPRi single guide RNA sequence against 5’-UTR of rat synaptotagmin-1 (Syt1) gene (insert 5’ - CACCAGTACTCGCGTGCCTCGCACCGG) (Syt1 Rat)
    Use
    CRISPR and Lentiviral
    Tags
    3xFlag (N-terminus of Cas9-KRAB), T2A-TagBFP2
    Expression
    Mutation
    Promoter
    Available since
    Dec. 12, 2024
    Availability
    Academic Institutions and Nonprofits only
    202555-plasmid-map-sequence-id-404691

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  3. pLV-RnSyt1-sgRNA3-dCas9-KRAB-TagBFP2 (Identifier AAAA-0247)

    Plasmid
    #202556
    Purpose
    Synaptotagmin-1 sgRNA3 with TagBFP2
    Depositor
    Frederic Meunier
    Article
    Joensuu et al EMBO J. 2023 Jul 3;42(13):e112095. doi:
    Insert
    CRISPRi single guide RNA sequence against 5’-UTR of rat synaptotagmin-1 (Syt1) gene (insert 5’ - CACCTCCTCCTGCAGCGGCAGCATCGG) (Syt1 Rat)
    Use
    CRISPR and Lentiviral
    Tags
    3xFlag (N-terminus of Cas9-KRAB), T2A-TagBFP2
    Expression
    Mutation
    Promoter
    Available since
    Dec. 12, 2024
    Availability
    Academic Institutions and Nonprofits only
    202556-plasmid-map-sequence-id-404689

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  4. pLV-RnSyt1-sgRNA1-dCas9-KRAB-TagBFP2 (identifier AAAA-0245)

    Plasmid
    #202554
    Purpose
    Synaptotagmin-1 sgRNA1 with TagBFP2
    Depositor
    Frederic Meunier
    Article
    Joensuu et al EMBO J. 2023 Jul 3;42(13):e112095. doi:
    Insert
    CRISPRi single guide RNA sequence against 5’-UTR of rat synaptotagmin-1 (Syt1) gene (insert 5’ -CACCGCGTGCCTCGCACCGGTCCGCGG) (Syt1 R. norvegius (gRNA))
    Use
    CRISPR and Lentiviral
    Tags
    3xFlag (N-terminus of Cas9-KRAB), T2A-TagBFP2
    Expression
    Mutation
    Promoter
    Available since
    Dec. 12, 2024
    Availability
    Academic Institutions and Nonprofits only
    202554-plasmid-map-sequence-id-404687

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  8. pEGFP-N1-HSD17B11-S172L-FLAGC

    Plasmid
    #161904
    Purpose
    Expresses the catalytically inactive S172L mutant of human HSD17B11 with a C-terminal FLAG-GFP tag. Confers G418 resistance.
    Depositor
    Sébastien Britton
    Article
    Demange et al Elife. 2022 May 10;11. pii: 73913. doi:
    Insert
    hydroxysteroid 17-beta dehydrogenase 11 (HSD17B11 Human)
    Use
    Tags
    FLAG-GFP
    Expression
    Mammalian
    Mutation
    S172L; catalytically dead mutant
    Promoter
    CMV
    Available since
    May 12, 2022
    Availability
    Academic Institutions and Nonprofits only
    161904-plasmid-map-sequence-id-320523

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  11. pLV[Exp]-Bsd-CMV>hCDK11B D562A

    Plasmid
    #239217
    Purpose
    Expresses CDK11B with D562A kinase inactivating mutation in mammalian cell lines
    Depositor
    Jason Sheltzer
    Article
    Julian et al bioRxiv 2025.08.03.668359; doi: https://
    Insert
    cyclin dependent kinase 11B with D562A kinase inactivating mutation (CDK11B Human)
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    changed Aspartic acid 562 to Alanine
    Promoter
    Available since
    Aug. 5, 2025
    Availability
    Academic Institutions and Nonprofits only
    239217-plasmid-map-sequence-id-474408

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  13. pLV[Exp]-Bsd-CMV>hCDK11B-p58 G579S

    Plasmid
    #239216
    Purpose
    Expresses CDK11B p58 isoform with G579S resistance mutation in mammalian cell lines
    Depositor
    Jason Sheltzer
    Article
    Julian et al bioRxiv 2025.08.03.668359; doi: https://
    Insert
    cyclin dependent kinase 11B p58 isoform with G579S resistance mutation (CDK11B Human)
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    changed Glycine 579 to Serine
    Promoter
    Available since
    Aug. 5, 2025
    Availability
    Academic Institutions and Nonprofits only
    239216-plasmid-map-sequence-id-474391

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  14. pLV[Exp]-Bsd-CMV>hCDK11B D562A, G579S

    Plasmid
    #239218
    Purpose
    Expresses CDK11B with D562A kinase inactivating mutation and G579S resistance mutation in mammalian cell lines
    Depositor
    Jason Sheltzer
    Article
    Julian et al bioRxiv 2025.08.03.668359; doi: https://
    Insert
    cyclin dependent kinase 11B with D562A kinase inactivating mutation and G579S resistance mutation (CDK11B Human)
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    changed Aspartic acid 562 to Alanine and changed …
    Promoter
    Available since
    Aug. 5, 2025
    Availability
    Academic Institutions and Nonprofits only
    239218-plasmid-map-sequence-id-476822

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  15. pLV-hUV6-sgRNA-dCas9-KRAB-TagBFP2 (identifier AAAA-0244)

    Plasmid
    #202553
    Purpose
    Nontargeting control vector with TagBFP2
    Depositor
    Frederic Meunier
    Article
    Joensuu et al EMBO J. 2023 Jul 3;42(13):e112095. doi:
    Insert
    Humanized dCas9-KRAB-TagBFP2 (tag blue fluorescent protein 2) (TRIM28 S. Pyogenes (dCas9), H. sapiens (KRAB), Entacmaea quadricolor (TagBFP2))
    Use
    CRISPR and Lentiviral
    Tags
    3xFlag (N-terminus of Cas9-KRAB), T2A-TagBFP2
    Expression
    Mutation
    Puromycin-resistance gene in the pLV hU6-sgRNA hU…
    Promoter
    Available since
    Dec. 12, 2024
    Availability
    Academic Institutions and Nonprofits only
    202553-plasmid-map-sequence-id-404692

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  16. pPMS-2272

    Plasmid
    #232292
    Purpose
    Protein Expression
    Depositor
    Jeremy Nathans
    Insert
    Alpha bungarotoxin
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    Feb. 20, 2025
    Availability
    Academic Institutions and Nonprofits only
    232292-plasmid-map-sequence-id-462102

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  17. pDEST-R4R3-MC1DTA

    Plasmid
    #139521
    Purpose
    Provides negative selection cassette on the vector
    Depositor
    Minoru Ko
    Type
    Empty backbone
    Use
    Mouse Targeting
    Tags
    Expression
    Mutation
    Promoter
    Available since
    March 19, 2020
    Availability
    Academic Institutions and Nonprofits only
    139521-plasmid-map-sequence-id-275144

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  18. pET-22b DT 51E/148K

    Plasmid
    #11081
    Depositor
    John Collier
    Insert
    DT
    Use
    Tags
    His
    Expression
    Bacterial
    Mutation
    51E/148K, catalytically inactive
    Promoter
    Available since
    Aug. 4, 2006
    Availability
    Academic Institutions and Nonprofits only
    11081-plasmid-map-sequence-id-306912

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  19. pBP-C_sacB

    Plasmid
    #204113
    Purpose
    Type 0 CDS part
    Depositor
    Mikhail Shapiro
    Insert
    Toxic levansucrase sacB
    Use
    Tags
    Expression
    Bacterial
    Mutation
    None
    Promoter
    Available since
    Jan. 3, 2024
    Availability
    Academic Institutions and Nonprofits only
    204113-plasmid-map-sequence-id-418236

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  20. pBP-C_ccdB

    Plasmid
    #204114
    Purpose
    Type 0 CDS part
    Depositor
    Mikhail Shapiro
    Insert
    Toxic DNA gyrase inhibitor ccdB
    Use
    Tags
    Expression
    Bacterial
    Mutation
    None
    Promoter
    Available since
    Jan. 3, 2024
    Availability
    Academic Institutions and Nonprofits only
    204114-plasmid-map-sequence-id-418238

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Showing: 1141 - 1160 of 1373 results