We narrowed to 26,787 results for: Vit

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NME1 gRNA (BRDN0001146284)

Plasmid

#75539

Purpose

3rd generation lentiviral gRNA plasmid targeting human NME1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

NME1,NME1-NME2 (NME1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR2B gRNA (BRDN0001147208)

Plasmid

#75485

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR2B

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR2B (ACVR2B Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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ACVR2B gRNA (BRDN0001149036)

Plasmid

#75486

Purpose

3rd generation lentiviral gRNA plasmid targeting human ACVR2B

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

ACVR2B (ACVR2B Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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IPMK gRNA (BRDN0001144988)

Plasmid

#78076

Purpose

3rd generation lentiviral gRNA plasmid targeting human IPMK

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IPMK (IPMK Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 5, 2016

Availability

Academic Institutions and Nonprofits only

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CHKA gRNA (BRDN0001145792)

Plasmid

#76586

Purpose

3rd generation lentiviral gRNA plasmid targeting human CHKA

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CHKA (CHKA Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

June 27, 2016

Availability

Academic Institutions and Nonprofits only

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CLK4 gRNA (BRDN0001145430)

Plasmid

#77797

Purpose

3rd generation lentiviral gRNA plasmid targeting human CLK4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CLK4 (CLK4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

June 24, 2016

Availability

Academic Institutions and Nonprofits only

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CLK4 gRNA (BRDN0001146113)

Plasmid

#77798

Purpose

3rd generation lentiviral gRNA plasmid targeting human CLK4

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

CLK4 (CLK4 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

June 24, 2016

Availability

Academic Institutions and Nonprofits only

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IP6K2 gRNA (BRDN0001146075)

Plasmid

#77816

Purpose

3rd generation lentiviral gRNA plasmid targeting human IP6K2

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

IP6K2 (IP6K2 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

June 24, 2016

Availability

Academic Institutions and Nonprofits only

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pcDNA3-Flag-NSF/T646A

Plasmid

#74937

Purpose

Mammalian expression of human NSF mutant T646A (mutation in the D2 domain of the protein)

Depositor

Elisa Greggio

Article

Belluzzi et al Mol Neurodegener. 2016 Jan 13;11(1):1. d

Insert

NSF (NSF Human)

Tags

FLAG

Expression

Mammalian

Mutation

T646A (mutation in the D2 domain of the protein)

Promoter

CMV

Available Since

April 26, 2016

Availability

Academic Institutions and Nonprofits only
pcDNA3.1 E2F1 Flag(Δ 284−359)(HindIII- BamHI- EcoRI)

Plasmid

#70669

Purpose

Human mutant of E2F1 lacking amino acids 284 to 359

Depositor

Maria Alvarado-Kristensson

Article

Hoog et al FASEB J. 2011 Nov;25(11):3815-27. doi: 1

Insert

E2F1 lacking residues 284 to 359 (E2F1 Human)

Tags

Flag

Expression

Mammalian

Mutation

lacks amin acids 284 to 359

Promoter

cmv

Available Since

Nov. 10, 2015

Availability

Academic Institutions and Nonprofits only
pCMV6-Entry IL36RN R48W

Plasmid

#58324

Purpose

entry vector for human IL36RN R48W mutant

Depositor

Francesca Capon

Article

Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

Insert

IL36RN (IL36RN Human)

Use

Entry vector

Tags

myc-DDK

Mutation

R48W: c.142C>T, p.Arg48Trp

Promoter

CMV

Available Since

July 30, 2014

Availability

Academic Institutions and Nonprofits only
pCMV6-Entry IL36RN P76L

Plasmid

#58322

Purpose

entry vector for human IL36RN P76L mutant

Depositor

Francesca Capon

Article

Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

Insert

IL36RN (IL36RN Human)

Use

Entry vector

Tags

myc-DDK

Mutation

P76L: c.227C>T,p.Pro76Leu

Promoter

CMV

Available Since

July 30, 2014

Availability

Academic Institutions and Nonprofits only
pCMV6-Entry IL36RN Κ35R

Plasmid

#58320

Purpose

entry vector for human IL36RN K35R mutant

Depositor

Francesca Capon

Article

Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

Insert

IL36RN (IL36RN Human)

Use

Entry vector

Tags

myc-DDK

Mutation

Κ35R: c.104A>G, p.Lys35Arg

Promoter

CMV

Available Since

July 25, 2014

Availability

Academic Institutions and Nonprofits only
pCMV5b HA Irx5 deltaIrot

Plasmid

#24995

Depositor

Benoit Bruneau

Article

Costantini et al Cell. 2005 Oct 21. 123(2):347-58.

Insert

Irx5 (Irx5 Mouse)

Tags

HA

Expression

Mammalian

Mutation

Deletion of Iro box (aa 314-327), 19 aa upstream …

Available Since

Aug. 2, 2010

Availability

Academic Institutions and Nonprofits only
pCMV5b HA Irx5 deltaC

Plasmid

#24996

Depositor

Benoit Bruneau

Article

Costantini et al Cell. 2005 Oct 21. 123(2):347-58.

Insert

Irx5 (Irx5 Mouse)

Tags

HA

Expression

Mammalian

Mutation

Deletes everything after Hox Domain (aa 112-177).…

Available Since

Aug. 2, 2010

Availability

Academic Institutions and Nonprofits only
p3xFLAG CMV14 / BRAF-G596C

Plasmid

#131712

Purpose

Mammalian Expression of Flag tagged BRAF

Depositor

Jacques De Grève

Article

Noeparast et al Oncotarget. 2016 Aug 26;8(36):60094-6010

Insert

BRAF (BRAF Human)

Tags

3xFLAG

Expression

Mammalian

Mutation

G596C

Promoter

CMV

Availability

Academic Institutions and Nonprofits only

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p3xFLAG CMV14 / BRAF-G469S

Plasmid

#131716

Purpose

Mammalian Expression of Flag tagged BRAF

Depositor

Jacques De Grève

Article

Noeparast et al Oncotarget. 2016 Aug 26;8(36):60094-6010

Insert

BRAF (BRAF Human)

Tags

3xFLAG

Expression

Mammalian

Mutation

G469S

Promoter

CMV

Availability

Academic Institutions and Nonprofits only

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p3xFLAG CMV14 / BRAF-V600R

Plasmid

#131721

Purpose

Mammalian Expression of Flag tagged BRAF

Depositor

Jacques De Grève

Article

Noeparast et al Oncotarget. 2016 Aug 26;8(36):60094-6010

Insert

BRAF (BRAF Human)

Tags

3xFLAG

Expression

Mammalian

Mutation

V600R

Promoter

CMV

Availability

Academic Institutions and Nonprofits only

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pLenti_EF1a_Flag_TP53_WT

Plasmid

#183112

Purpose

Expresses flag-tagged p53 in mammalian cells

Depositor

William Kaelin

Article

Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

Insert

TP53 (TP53 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

See Depositor Comments Below

Promoter

EF1a

Available Since

Aug. 24, 2022

Availability

Academic Institutions and Nonprofits only

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Tet-Inducible Human Caspase-9 Alpha C287A Mutant

Plasmid

#194709

Purpose

Inducible Expression of Human Caspase-9 Alpha C287A Mutant

Depositor

Hannah Rabinowich

Article

Han et al J Biol Chem. 2014 Mar 7;289(10):6485-649

Insert

Human Caspase-9 C287A Mutant (CASP9 Human)

Tags

None

Expression

Mammalian

Mutation

Changed Cysteine 287 to Alanine to eliminate prot…

Promoter

CMV

Available Since

Feb. 17, 2023

Availability

Academic Institutions and Nonprofits only

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