We narrowed to 3,140 results for: GAI

1. pSIREN-RetroQ-CDK4-shRNA

   Plasmid

   #25788

   Depositor

   Judy Lieberman

   Article

   Navarro et al Blood. 2009 Sep 3. 114(10):2181-92.

   Insert

   shRNA against human CDK4 (CDK4 Human)
   

   Use

   RNAi and Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   July 13, 2010

   Availability

   Academic Institutions and Nonprofits only

2. T7 promoter + rpsL reporter plasmid

   Plasmid

   #156455

   Purpose

   A mutational reporter plasmid that can gain Streptomycin and/or Tetracycline resistance upon mutation. Contains T7 promoter.

   Depositor

   Matthew D. Shoulders

   Article

   Moore et al J Am Chem Soc. 2018 Sep 19;140(37):11560

   Inserts

   rpsL
   TcR
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   ATG start codon mutated to ACG

   Promoter

   tac and tet

   Available Since

   Oct. 21, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLKO.1p shDna2

   Plasmid

   #31951

   Depositor

   Sheila Stewart

   Article

   Duxin et al Mol Cell Biol. 2009 Aug;29(15):4274-82.

   Insert

   shRNA against hDna2 (DNA2 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   Sept. 19, 2011

   Availability

   Academic Institutions and Nonprofits only

4. pSIREN-RetroQ-CDK6-shRNA

   Plasmid

   #25789

   Depositor

   Judy Lieberman

   Article

   Navarro et al Blood. 2009 Sep 3. 114(10):2181-92.

   Insert

   shRNA against human CDK6 (CDK6 Human)
   

   Use

   RNAi and Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   July 13, 2010

   Availability

   Academic Institutions and Nonprofits only

5. pQsupR-Mi2b

   Plasmid

   #15379

   Depositor

   Stephen Smale

   Article

   Ramirez-Carrozzi et al Genes Dev. 2006 Feb 1. 20(3):282-96.

   Insert

   short hairpin RNA against mouse Mi-2 beta (Chd4 Mouse)
   

   Use

   RNAi and Retroviral

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   April 18, 2008

   Availability

   Academic Institutions and Nonprofits only

6. pLKO.1-sh-mSox10-2

   Plasmid

   #37007

   Depositor

   Bob Weinberg

   Article

   Guo et al Cell. 2012 Mar 2;148(5):1015-28.

   Insert

   sh-mSox10-2 (Sox10 Mouse)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   May 31, 2012

   Availability

   Academic Institutions and Nonprofits only

7. PCTAIRE-1-DN-HA

   Plasmid

   #1998

   Depositor

   Sander van den Heuvel

   Article

   van den Heuvel et al Science 1993 Dec 24;262(5142):2050-4.

   Insert

   PCTAIRE-1 (CDK16 Human)
   

   Use

   Tags

   HA

   Expression

   Mammalian

   Mutation

   Dominant negative, D304N in conserved KLAD*FGLAR …

   Promoter

   Available Since

   Jan. 24, 2006

   Availability

   Academic Institutions and Nonprofits only

8. pTRIPZ-DoxOn-shCUX1-5150

   Plasmid

   #90469

   Purpose

   Lentiviral vector expressing a doxycycline-inducible shRNA against human CUX1 sequence starting at 5150 of M74099

   Depositor

   Alain Nepveu

   Article

   Ramdzan et al PLoS Biol. 2014 Mar 11;12(3):e1001807. d

   Insert

   TGCTGTTGACAGTGAGCGTCAGAGCGATAATACACTATTATAGTGAAGCC
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   March 16, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. p-mCherry2-sgC9cen

   Plasmid

   #198326

   Purpose

   Expresses a guide RNA against a repetitive locus found in the pericentromere of human chromosome 9, with mCherry2 reporter

   Depositor

   Sarah McClelland

   Article

   Tovini et al EMBO J. 2023 May 15;42(10):e111587. doi:

   Insert

   Chr9-CEN guide RNA
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   May 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pTRIPZ shCUX1-5328

    Plasmid

    #100815

    Purpose

    Lentiviral vector expressing a doxycycline-inducible short hairpin RNA against CUX1 sequence starting at 5328 of M74099

    Depositor

    Alain Nepveu

    Article

    Ramdzan et al PLoS Biol. 2014 Mar 11;12(3):e1001807. d

    Insert

    TGCTGTTGACAGTGAGCGTCTTCTCGTTTGAAACTTTGAATAGTGAAGCCA
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    March 16, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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11. lentiCRISPR - Amplicon, BCR/ABL sgRNA 1

    Plasmid

    #70659

    Purpose

    Expresses human codon-optimized Cas9 protein and puromycin resistance from EFS promoter and an intergenic BCR/ABL-targeting sgRNA element from U6 promoter. Lentiviral backbone

    Depositor

    David Sabatini

    Article

    Wang et al Science. 2015 Oct 15. pii: aac7041.

    Insert

    sgRNA against BCR/ABLamplicon found in CML-derived K562 cell line
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 13, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pResQ shDna2'

    Plasmid

    #31952

    Depositor

    Sheila Stewart

    Article

    Duxin et al Mol Cell Biol. 2009 Aug;29(15):4274-82.

    Insert

    shRNA against hDna2 (DNA2 Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Sept. 19, 2011

    Availability

    Academic Institutions and Nonprofits only

13. miR-144 Trap

    Plasmid

    #60934

    Purpose

    to knockdown endogenous miR144 levels; lentiviral vector containing 8x copies of complementary miR-144-binding sites cloned 3' to GFP under the control of a biPGK promoter

    Depositor

    Curt Civin

    Article

    Kim et al Br J Haematol. 2014 Oct 14. doi: 10.1111

    Insert

    miR-144 Trap
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Mutation

    Promoter

    bidirectional phosphoglycerate kinase promoter (b…

    Available Since

    Oct. 20, 2015

    Availability

    Academic Institutions and Nonprofits only

14. pCEP4-SERTS585P-myc

    Plasmid

    #107498

    Purpose

    Mammalian expression plasmid for codon optimized mutant hSERT with internal MYC tag inserted in ECL2, mutation S585P conferring gain of function phenotype

    Depositor

    Erik Procko

    Article

    Young et al bioRxiv 2021.04.19.440442

    Insert

    Serotonin Transporter (SERT) (SLC6A4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    S585P

    Promoter

    CMV

    Available Since

    March 15, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. PX458_MBD1_iso1_2

    Plasmid

    #86304

    Purpose

    Encodes gRNA for 3' target of human MBD1_iso1

    Depositor

    Eric Mendenhall, Richard M. Myers

    Article

    Savic et al Genome Res. 2015 Sep 9.

    Insert

    gRNA against MBD1_iso1 (MBD1 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Jan. 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. PCTAIRE-1-DN

    Plasmid

    #1997

    Depositor

    Sander van den Heuvel

    Article

    van den Heuvel et al Science 1993 Dec 24;262(5142):2050-4.

    Insert

    PCTAIRE-1 (CDK16 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Dominant negative, D304N in conserved KLAD*FGLAR …

    Promoter

    Available Since

    Jan. 24, 2006

    Availability

    Academic Institutions and Nonprofits only

17. PX458_GATAD2A_2

    Plasmid

    #86334

    Purpose

    Encodes gRNA for 3' target of human GATAD2A

    Depositor

    Eric Mendenhall, Richard M. Myers

    Article

    Savic et al Genome Res. 2015 Sep 9.

    Insert

    gRNA against GATAD2A (GATAD2A Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Jan. 27, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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18. PX458_GATAD2A_1

    Plasmid

    #86333

    Purpose

    Encodes gRNA for 3' target of human GATAD2A

    Depositor

    Eric Mendenhall, Richard M. Myers

    Article

    Savic et al Genome Res. 2015 Sep 9.

    Insert

    gRNA against GATAD2A (GATAD2A Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Jan. 27, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. TU#1806_CRISPR_unc-73_exon21

    Plasmid

    #82360

    Purpose

    to create unc-73E null allele

    Depositor

    Martin Chalfie

    Article

    Zheng et al Proc Natl Acad Sci U S A. 2016 Jun 21;11

    Insert

    Cas9 and sgRNA against unc-73 exon21 (unc-73 Nematode)
    

    Use

    CRISPR

    Tags

    Expression

    Worm

    Mutation

    Promoter

    U6

    Available Since

    Sept. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. PX458_MBD1_iso1_1

    Plasmid

    #86303

    Purpose

    Encodes gRNA for 3' target of human MBD1_iso1

    Depositor

    Eric Mendenhall, Richard M. Myers

    Article

    Savic et al Genome Res. 2015 Sep 9.

    Insert

    gRNA against MBD1_iso1 (MBD1 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 9, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. PX458_HLF_2

    Plasmid

    #86302

    Purpose

    Encodes gRNA for 3' target of human HLF

    Depositor

    Eric Mendenhall, Richard M. Myers

    Article

    Savic et al Genome Res. 2015 Sep 9.

    Insert

    gRNA against HLF (HLF Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Feb. 27, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. PX458_HLF_1

    Plasmid

    #86301

    Purpose

    Encodes gRNA for 3' target of human HLF

    Depositor

    Eric Mendenhall, Richard M. Myers

    Article

    Savic et al Genome Res. 2015 Sep 9.

    Insert

    gRNA against HLF (HLF Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Jan. 27, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pT7-gRNA_zebrafish_mmp21

    Plasmid

    #72890

    Purpose

    plasmid to generate guideRNA against mmp21 gene in zebrafish

    Depositor

    Nicholas Katsanis

    Article

    Perles et al J Med Genet. 2015 Dec;52(12):840-7. doi:

    Insert

    zebrafish mmp21 (mmp21 Zebrafish)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    T7 RNA pol

    Available Since

    Feb. 16, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pSicoR-ADAM7i1

    Plasmid

    #59602

    Purpose

    Expression of shRNA against human ADAM7

    Depositor

    Miguel Ramalho-Santos

    Article

    Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

    Insert

    ADAM7 (ADAM7 Human)
    

    Use

    RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available Since

    Sept. 26, 2014

    Availability

    Academic Institutions and Nonprofits only

25. pLKO.1C-YFP-shRB1-733

    Plasmid

    #244458

    Purpose

    Expresses EYFP and an shRNA against RB1 in mammalian cells

    Depositor

    David Cobrinik

    Article

    Lee et al Biotechniques. 2020 Jun;68(6):349-352. d

    Insert

    shRB1 (RB1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    CMV

    Available Since

    Sept. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. PX459-sgRNA047_Podxl

    Plasmid

    #232932

    Purpose

    Expression vector for a sgRNA against the mouse Podxl locus and SpCas9 with T2A-Puromycin resistance gene.

    Depositor

    Danny Reinberg

    Article

    Lucero et al bioRxiv, March 19, 2025

    Insert

    Cas9-T2A-PuroR (Podxl S. pyogenes)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. PX458-eBFP2-sgRNA_CTCF_ZF1

    Plasmid

    #233090

    Purpose

    Expression vector for a sgRNA against the mouse CTCF ZF1 region and SpCas9-T2A-eBFP2.

    Depositor

    Danny Reinberg

    Article

    Lucero et al bioRxiv, March 19, 2025

    Insert

    spCas9-T2A-eBFP2 (Ctcf )
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    March 26, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pGM65

    Plasmid

    #220170

    Purpose

    CRISRPi guide RNA against NACA

    Depositor

    Jonathan Weissman

    Article

    Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

    Insert

    NACA (sgRNA) (NACA Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Feb. 25, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pAG157

    Plasmid

    #226746

    Purpose

    CRISPRi guide RNA against TOMM22

    Depositor

    Jonathan Weissman

    Article

    Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

    Insert

    TOMM22 (TOMM22 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Oct. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pGM133

    Plasmid

    #220173

    Purpose

    CRISRPi guide RNA against TTC1

    Depositor

    Jonathan Weissman

    Article

    Muthukumar et al Mol Cell. 2024 Mar 21;84(6):1101-1119.e9

    Insert

    TTC1 (sgRNA) (TTC1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    June 7, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge