We narrowed to 17,819 results for: Mut
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Plasmid#84006PurposeDonor HR template carrying a 2,080 bp fragment of the Drosophila melanogaster white[coffee] allele and silent mutations conferring resistance to white sgRNAs-1, -2, -3, and -4DepositorInsertA 2,080 bp fragment of the white[coffee] allele (w Fly)
UseUnspecifiedTagsExpressionMutationA GC-to-AA mutation that creates a G589E missense…PromoterAvailable SinceNov. 8, 2016AvailabilityAcademic Institutions and Nonprofits only -
2XMyc-LRRK2-3XKD/Y1699C
Plasmid#25367DepositorInsertLRRK2 (LRRK2 Human)
UseTags2XMycExpressionMammalianMutation"Kinase Dead" Lysine 1906 mutated to A…PromoterAvailable SinceJune 29, 2010AvailabilityAcademic Institutions and Nonprofits only -
pWZL-hygro-FAKY925F
Plasmid#216547PurposeThis retroviral plasmid expresses a mutated cDNA (dominant negative: Y925F ) of human PTK2DepositorInsertPTK2 (Y925F) (PTK2 Human)
UseRetroviralTagsNoExpressionMammalianMutationFAK dominant negative mutation Y925FPromoterAvailable SinceSept. 16, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCas9-beta-mmr
Plasmid#169241PurposeCas9, beta, and mutL mutant expression plasmid for introducing chromosomal point mutationsDepositorInsertscas9
beta
mutL-E36K
UseCRISPR and Synthetic BiologyTagsExpressionBacterialMutationChanged glutamic acid 36 to lysinePromoterAvailable SinceJune 16, 2021AvailabilityAcademic Institutions and Nonprofits only -
pKIF1C_P176L-GFP
Plasmid#185980PurposeMammalian expression of human KIF1C with P176L mutation and GFP tag.DepositorInsertKIF1C (KIF1C Human)
UseTagseGFPExpressionMammalianMutationP176L - mutation causing HSP (SPG58)PromoterCMVAvailable SinceJuly 6, 2022AvailabilityAcademic Institutions and Nonprofits only -
pTSlb-Q758C
Plasmid#60729PurposeExpresses both fragments of T7 RNAP split at position 179. The N-terminal fragment is driven by PLac while the C-terminal fragment is driven by PBAD. C-terminal fragment has the point mutations Q758CDepositorInsertsResidues 1-179 of split T7 RNAP
Residues 180-880 of split T7 RNAP
UseSynthetic BiologyTagsExpressionBacterialMutationResidues 1-180 of split T7 RNAP and Residues 180-…PromoterAvailable SinceNov. 4, 2014AvailabilityAcademic Institutions and Nonprofits only -
pCEP4-CH115gp160-QES.c14-754*
Plasmid#123282PurposeMammalian expression plasmid for Env from the CH115 HIV-1 isolate; C-terminal truncation; QES mutant for enhanced presentation of quaternary epitopesDepositorInsertHIV-1 (CH115) Env
UseTagsCD5 leader peptideExpressionMammalianMutationCodon-optimized synthetic gene; Premature stop co…PromoterCMVAvailable SinceMarch 28, 2019AvailabilityAcademic Institutions and Nonprofits only -
pET22b-ecDHFR-N23PP/L28F/G51PEKN
Plasmid#118585PurposeBacterial expression of E.coli DHFR N23PP, L28F, and G51PEKN mutantDepositorInsertDHFR
UseTagsExpressionBacterialMutationN23 mutated to P23, L28 mutated to F28, G51 mutat…PromoterT7Available SinceNov. 29, 2018AvailabilityAcademic Institutions and Nonprofits only -
pTSara-R756K
Plasmid#60727PurposeExpresses both fragments of T7 RNAP split at position 179. Both fragments are driven by PBAD. The C-terminal fragment has the point mutation R756K. Contains a constitutive araC ORFDepositorInsertsResidues 1-179 of split T7 RNAP
Residues 180-880 of split T7 RNAP
UseSynthetic BiologyTagsExpressionBacterialMutationResidues 1-180 of split T7 RNAP and Residues 180-…PromoterAvailable SinceOct. 2, 2015AvailabilityAcademic Institutions and Nonprofits only -
pCDF1-ADAM29 (wt)
Plasmid#31143DepositorAvailable SinceJuly 22, 2011AvailabilityAcademic Institutions and Nonprofits only -
pCDF1-PTPRD-P459L
Plasmid#25644DepositorInsertProtein tyrosine phosphatase receptor-type delta (PTPRD Human)
UseLentiviralTagsExpressionMammalianMutationtumor-derived mutation created by site-directed m…PromoterAvailable SinceJuly 14, 2010AvailabilityAcademic Institutions and Nonprofits only -
pCDF1-PTPRD-D1248N
Plasmid#25646DepositorInsertProtein tyrosine phosphatase receptor-type delta (PTPRD Human)
UseLentiviralTagsExpressionMammalianMutationtumor-derived mutation created by site-directed m…PromoterAvailable SinceNov. 8, 2010AvailabilityAcademic Institutions and Nonprofits only -
pTSlb-R756K
Plasmid#60731PurposeExpresses both fragments of T7 RNAP split at position 179. The N-terminal fragment is driven by PLac while the C-terminal fragment is driven by PBAD. C-terminal fragment has the point mutations R756SDepositorInsertsResidues 1-179 of split T7 RNAP
Residues 180-880 of split T7 RNAP
UseSynthetic BiologyTagsExpressionBacterialMutationResidues 1-180 of split T7 RNAP and Residues 180-…PromoterAvailable SinceNov. 4, 2014AvailabilityAcademic Institutions and Nonprofits only -
pTSara-N748D
Plasmid#60726PurposeExpresses both fragments of T7 RNAP split at position 179. Both fragments are driven by PBAD. The C-terminal fragment has the point mutation N748D. Contains a constitutive araC ORFDepositorInsertsResidues 1-179 of split T7 RNAP
Residues 180-880 of split T7 RNAP
UseSynthetic BiologyTagsExpressionBacterialMutationResidues 1-180 of split T7 RNAP and Residues 180-…PromoterAvailable SinceOct. 2, 2015AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-ADAM7 (H243Y)
Plasmid#31138DepositorInsertADAM7 (ADAM7 Human)
UseTagsFLAGExpressionMammalianMutationHistidine 243 changed to TyrosinePromoterAvailable SinceSept. 1, 2011AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-IARS2-H112A/P115A
Plasmid#232338PurposeExpresses human IARS2 with putative isoleucine binding deficiency mutations (H112A and P115A) in mammalian cells, also carrying synonymous mutations described in Addgene #232340DepositorInsertIARS2 (IARS2 Human)
UseTagsExpressionMammalianMutationPutative isoleucine binding deficiency mutation H…PromoterCMVAvailable SinceJune 9, 2025AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-IARS2-K664A/K667A
Plasmid#232339PurposeExpresses human IARS2 with putative tRNA binding deficiency mutations (K664A and K667A) in mammalian cells, also carrying synonymous mutations described in Addgene #232340DepositorInsertIARS2 (IARS2 Human)
UseTagsExpressionMammalianMutationPutative tRNA binding deficiency mutation K664A A…PromoterCMVAvailable SinceJune 9, 2025AvailabilityAcademic Institutions and Nonprofits only -
pWZL-hygro-FAKS722A
Plasmid#216545PurposeThis retroviral plasmid expresses a mutated cDNA (dominant negative: S722A) of human PTK2DepositorInsertPTK2 (S722A) (PTK2 Human)
UseRetroviralTagsNoExpressionMammalianMutationFAK dominant negative mutation S722APromoterAvailable SinceSept. 16, 2024AvailabilityAcademic Institutions and Nonprofits only -
pWZL-hygro-FAKY861F
Plasmid#216546PurposeThis retroviral plasmid expresses a mutated cDNA (dominant negative: Y861F) of human PTK2DepositorInsertPTK2 (Y861F) (PTK2 Human)
UseRetroviralTagsNoExpressionMammalianMutationFAK dominant negative mutation Y861FPromoterAvailable SinceSept. 16, 2024AvailabilityAcademic Institutions and Nonprofits only -
pWZL-hygro-FAKY397F
Plasmid#216677PurposeThis retroviral plasmid expresses a mutated cDNA (dominant negative: Y397F) of human PTK2DepositorInsertPTK2 (Y397F) (PTK2 Human)
UseRetroviralTagsNoExpressionMammalianMutationFAK dominant negative mutation Y397FPromoterAvailable SinceSept. 16, 2024AvailabilityAcademic Institutions and Nonprofits only