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pTC7-dmd-1

Plasmid

#44689

Depositor

Phillip Newmark

Article

Chong et al Nat Commun. 2013; 4:1814. doi: 10.1038/n

Insert

Smed-dmd-1, 3’ RACE partial product

Use

T/a cloning vector for dsrna generation and the g…

Tags

Expression

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only
pTC62.6-dmd-1, full ORF, splice form 1

Plasmid

#45028

Depositor

Phillip Newmark

Article

Chong et al Nat Commun. 2013; 4:1814. doi: 10.1038/n

Insert

Smed-dmd-1, full ORF, spice form 1

Use

T/a cloning vector for dsrna generation and the g…

Tags

Expression

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only
pTC16-dmd-1, splice form 3

Plasmid

#44694

Depositor

Phillip Newmark

Article

Chong et al Nat Commun. 2013; 4:1814. doi: 10.1038/n

Insert

Smed-dmd-1, spice form 3

Use

T/a cloning vector for dsrna generation and the g…

Tags

Expression

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only
pTC17-dmd-1, splice form 2

Plasmid

#44695

Depositor

Phillip Newmark

Article

Chong et al Nat Commun. 2013; 4:1814. doi: 10.1038/n

Insert

Smed-dmd-1, spice form 2

Use

T/a cloning vector for dsrna generation and the g…

Tags

Expression

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only
PL-5LTR-RGR(DMD#1)-AmCyan-A

Plasmid

#138482

Purpose

Expresses sgRNA targeting human DMD (Dystrophin) for packaging into NanoMEDIC particle.

Depositor

Akitsu Hotta

Article

Gee et al Nat Commun. 2020 Mar 13;11(1):1334. doi:

Insert

Ribozyme-flanked gRNA and AmCyan

Use

CRISPR

Tags

Expression

Mammalian

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only

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AL08_pgRNA.DMD

Plasmid

#100293

Purpose

DMD intron 43-targeting gRNA expression plasmid

Depositor

Manuel Goncalves

Article

Chen et al Nat Commun. 2017 Sep 22;8(1):657. doi: 1

Insert

gRNA spacer

Use

CRISPR and Synthetic Biology

Tags

Expression

Mammalian

Mutation

Promoter

human U6 Polymerase III snRNA

Availability

Academic Institutions and Nonprofits only

Enlarge
AL05_pDonor.DMD

Plasmid

#100284

Purpose

DMD intron 43-targeting plasmid

Depositor

Manuel Goncalves

Article

Chen et al Nat Commun. 2017 Sep 22;8(1):657. doi: 1

Insert

EGFP expression unit (DMD Synthetic, Human)

Use

CRISPR and Synthetic Biology; Human targeting

Tags

Expression

Mammalian

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only

Enlarge
AL62_pDonor.DMD.TS

Plasmid

#100287

Purpose

DMD intron 43-targeting plasmid

Depositor

Manuel Goncalves

Article

Chen et al Nat Commun. 2017 Sep 22;8(1):657. doi: 1

Insert

EGFP expression unit (DMD Synthetic, Human)

Use

CRISPR and Synthetic Biology; Human targeting

Tags

Expression

Mammalian

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only

Enlarge
AC62_pDonor.DMD.TS.DR

Plasmid

#100288

Purpose

DMD intron 43-targeting plasmid

Depositor

Manuel Goncalves

Article

Chen et al Nat Commun. 2017 Sep 22;8(1):657. doi: 1

Insert

EGFP expression unit (DMD Synthetic, Human)

Use

CRISPR and Synthetic Biology; Human targeting

Tags

Expression

Mammalian

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only

Enlarge
AAV2 ITR_phU6_gRNA scaffold-DMD sg1_phU6_gRNA scaffold-DMD sg16_pMHCK7-3x Flag-NLS-enOsCas12f1-NLS_pA_AAV2 ITR

Plasmid

#197028

Purpose

AAV vector encoding a human codon-optimized enOsCas12f1 driven by MHCK7 promoter, DMD-targeting guide RNAs compatible with enOsCas12f1 driven by hU6

Depositor

Xiangfeng Kong

Article

Kong et al Nat Commun. 2023 Apr 11;14(1):2046. doi:

Insert

humanized enOsCas12f1

Use

AAV

Tags

Expression

Mutation

D52R / T132R

Promoter

MHCK7, hU6

Availability

Academic Institutions and Nonprofits only

Enlarge
pTC62.13-dmd-1, full ORF, splice form 4

Plasmid

#44688

Depositor

Phillip Newmark

Article

Chong et al Nat Commun. 2013; 4:1814. doi: 10.1038/n

Insert

Smed-dmd-1, full ORF, spice form 4

Use

T/a cloning vector for dsrna generation and the g…

Tags

Expression

Mutation

Promoter

Availability

Academic Institutions and Nonprofits only
pMSCV-GSDMD-Myc

Plasmid

#201166

Purpose

Expression of GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D (Gsdmd Mouse)

Use

Retroviral

Tags

Myc

Expression

Mutation

Promoter

MESV

Availability

Academic Institutions and Nonprofits only

Enlarge
pMSCV-GSDMD_C39A-Myc

Plasmid

#201167

Purpose

Expression of GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D (Gsdmd Mouse)

Use

Retroviral

Tags

Myc

Expression

Mutation

C39A

Promoter

MESV

Availability

Academic Institutions and Nonprofits only

Enlarge
pMSCV-GSDMD_C192A-Myc

Plasmid

#201168

Purpose

Expression of GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D (Gsdmd Mouse)

Use

Retroviral

Tags

Myc

Expression

Mutation

C192A

Promoter

MESV

Availability

Academic Institutions and Nonprofits only

Enlarge
pMSCV-GSDMD_NoCys-Myc

Plasmid

#201169

Purpose

Expression of GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D (Gsdmd Mouse)

Use

Retroviral

Tags

Myc

Expression

Mutation

C39A, C57A, C77A, C122A, C265A, C192A

Promoter

MESV

Availability

Academic Institutions and Nonprofits only

Enlarge
pRetroX-TRE3G_NT-GSDMD

Plasmid

#201170

Purpose

Dox-inducible expression of NT-GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D N-terminal domain (Gsdmd Mouse)

Use

Retroviral

Tags

Expression

Mutation

aa1-276 only

Promoter

TRE3G

Availability

Academic Institutions and Nonprofits only

Enlarge
pRetroX-TRE3G_NT-GSDMD_C39A

Plasmid

#201171

Purpose

Dox-inducible expression of NT-GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D N-terminal domain (Gsdmd Mouse)

Use

Retroviral

Tags

Expression

Mutation

aa1-276 only, C39A

Promoter

TRE3G

Availability

Academic Institutions and Nonprofits only

Enlarge
pRetroX-TRE3G_NT-GSDMD_C192A

Plasmid

#201172

Purpose

Dox-inducible expression of NT-GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D N-terminal domain (Gsdmd Mouse)

Use

Retroviral

Tags

Expression

Mutation

aa1-276 only, C192A

Promoter

TRE3G

Availability

Academic Institutions and Nonprofits only

Enlarge
pRetroX-TRE3G_NT-GSDMD_NoCys

Plasmid

#201173

Purpose

Dox-inducible expression of NT-GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D N-terminal domain (Gsdmd Mouse)

Use

Retroviral

Tags

Expression

Mutation

aa1-276 only, C39A, C57A, C77A, C122A, C265A, C19…

Promoter

TRE3G

Availability

Academic Institutions and Nonprofits only

Enlarge
pRetroX-TRE3G_NT-GSDMD_I105N_

Plasmid

#201174

Purpose

Dox-inducible expression of NT-GSDMD gene in mammalian cells by retroviral transduction

Depositor

Jonathan Kagan

Article

Devant et al Cell Rep. 2023 Jan 31;42(1):112008. doi:

Insert

Gasdermin D N-terminal domain (Gsdmd Mouse)

Use

Retroviral

Tags

Expression

Mutation

aa1-276 only, I105N

Promoter

TRE3G

Availability

Academic Institutions and Nonprofits only

Enlarge