We narrowed to 241 results for: Gene

1. TP53 MITE Library

   Pooled Library

   #113569

   Purpose

   Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

   Depositor

   David Root, William Hahn

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

2. plIG-123_HA-GD2-28z_CAR_TF_Library

   Pooled Library

   #207478

   Purpose

   HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

3. plIG-128_HA-GD2-28z_CAR_TFxTF_Library

   Pooled Library

   #207480

   Purpose

   HA-GD2-28z CAR in combination with ~10,000 transcription factor combinations (and related proteins) and controls (GFP/RFP combinations). Library can be used to generate HDR templates for modular poole

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Use

   CRISPR

   Available Since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

4. plIG-106_NY-ESO-1_TCR_SR_Library

   Pooled Library

   #207474

   Purpose

   NY-ESO-1 TCR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

5. plIG-107_NY-ESO-1_TCR_TF_Library

   Pooled Library

   #207475

   Purpose

   NY-ESO-1 TCR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

6. plIG-109_CD19-BBz_CAR_SR_Library

   Pooled Library

   #207476

   Purpose

   CD19-BBz CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Use

   CRISPR

   Available Since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

7. plIG-110_CD19-BBz_CAR_TF_Library

   Pooled Library

   #207477

   Purpose

   CD19-BBz CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

8. plIG-124_HA-GD2-28z_CAR_SR_Library

   Pooled Library

   #207479

   Purpose

   HA-GD2-28z CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cel

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

9. plIG-132_CD19-28z_CAR_TF_and_SR_Library

   Pooled Library

   #207481

   Purpose

   CD19-28z CAR in combination with 129 surface receptors, 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knoc

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

10. Human genome-wide lentiviral CRISPR gRNA library version 1

    Pooled Library

    #67989

    Purpose

    Human genome-wide CRISPR guide RNA library V1 (pKLV2-U6gRNA5(HumanV1)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

11. Mouse genome-wide lentiviral CRISPR gRNA library version 2

    Pooled Library

    #67988

    Purpose

    Mouse genome-wide CRISPR guide RNA library V2. (pKLV2-U6gRNA5(MouseV2)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

12. Green monkey (Chlorocebus sabaeus) sgRNA library

    Pooled Library

    #178284

    Purpose

    Genome-wide CRISPR screening library targeting 20,991 genes in C. sabaeus, 84,963 total gRNAs

    Depositor

    David Root, John Doench

    Article

    Wei et al Cell. 2021 Jan 7;184(1):76-91.e13. doi:

    Expression

    Mammalian

    Species

    Chlorocebus sabaeus (african green monkey)

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 23, 2021

    Availability

    Academic Institutions and Nonprofits only

13. TUNEYALI-TF Library

    Pooled Library

    #217744

    Purpose

    Regulating transcription factors in Yarrowia lipolytica

    Depositor

    Irina Borodina

    Expression

    Yeast

    Available Since

    May 20, 2025

    Availability

    Academic Institutions and Nonprofits only

14. Mouse SLC KO Library

    Pooled Library

    #141436

    Purpose

    Expresses gRNAs for knockout of the mouse Solute Carrier family

    Depositor

    Giulio Superti-Furga

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    May 18, 2020

    Availability

    Academic Institutions and Nonprofits only

15. TRE-MPRA_minCMV Library

    Pooled Library

    #201012

    Purpose

    Massively parallel reporter assay (MPRA) library with minCMV promoter

    Depositor

    Justin English

    Article

    Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

    Expression

    Mammalian

    Use

    Luciferase

    Available Since

    Oct. 31, 2023

    Availability

    Academic Institutions and Nonprofits only

16. TRE-MPRA_minPromega Library

    Pooled Library

    #201013

    Purpose

    Massively parallel reporter assay (MPRA) library with minPromega promoter

    Depositor

    Justin English

    Article

    Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

    Expression

    Mammalian

    Use

    Luciferase

    Available Since

    Oct. 31, 2023

    Availability

    Academic Institutions and Nonprofits only

17. TRE-MPRA_minTK Library

    Pooled Library

    #201014

    Purpose

    Massively parallel reporter assay (MPRA) library with minTK promoter

    Depositor

    Justin English

    Article

    Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

    Expression

    Mammalian

    Use

    Luciferase

    Available Since

    Oct. 31, 2023

    Availability

    Academic Institutions and Nonprofits only

18. Human ubiquitination-related proteins CRISPR KO library

    Pooled Library

    #174592

    Purpose

    CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.

    Depositor

    Juan Bonifacino

    Article

    Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

19. Ingolia lab S cerevisiae CRISPRi v1 – barcodes 181005

    Pooled Library

    #161769

    Purpose

    Inducible CRISPRi library

    Depositor

    Nicholas Ingolia

    Article

    McGlincy et al BMC Genomics. 2021 Mar 23;22(1):205. doi

    Expression

    Yeast

    Species

    Saccharomyces cerevisiae

    Use

    CRISPR

    Available Since

    Nov. 30, 2021

    Availability

    Academic Institutions and Nonprofits only

20. Human Whole Genome sgRNA iBAR Library

    Pooled Library

    #140633

    Purpose

    CRISPR pooled screen at high MOI by the embedded internal barcodes

    Depositor

    Wensheng Wei

    Article

    Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

    Use

    CRISPR and Lentiviral

    Available Since

    April 21, 2020

    Availability

    Academic Institutions and Nonprofits only