We narrowed to 74 results for: CAN

#115927

~93,000 gRNAs targeting random positions along the genome of E. coli MG1655 with a NGG PAM motif. Contains ~19 targets per gene and can be used with SpdCas9 to perform pooled CRISPRi screens.

David Bikard

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

June 6, 2019

Academic Institutions and Nonprofits only

#160134

Plasmid library harboring a randomized 10nt PAM 5’ of target site 3. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#160132

Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#160135

Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#160133

Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#123361

CRISPR-Cpf1/Cas12a double knockout library. Targets 26 genes, chosen from analysis of human metastasis cohorts. It can be used to interrogate the genetic interactions driving metastasis.

Sidi Chen

Chow et al Nat Methods. 2019 May;16(5):405-408. doi

June 10, 2019

Academic Institutions and Nonprofits only

#227193

Two-way barcodes from 18 fluorescent proteins for mammalian expression. Can be used for clone tracing, or for pairing with perturbations for single cell resolution in spectral detection measurements.

Marc Birtwistle

Lu et al ACS Synth Biol. 2025 May 16;14(5):1533-1

Dec. 18, 2024

Academic Institutions and Nonprofits only

#178943

Barcoding library for the macsGESTALT inducible lineage recording system

Christopher Lengner

Simeonov et al Cancer Cell. 2021 Aug 9;39(8):1150-1162.

March 22, 2022

Academic Institutions and Nonprofits only

#179218

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Lukas Dow

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

June 16, 2022

Academic Institutions and Nonprofits only

#179217

sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

Lukas Dow

Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

June 16, 2022

Academic Institutions and Nonprofits only

#224585

Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

Ryan Mehl

Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

Jan. 6, 2025

Academic Institutions and Nonprofits only

#159391

Targets 182 immune evasion genes. Designed for loss-of-function screening against genes shown to increase sensistivity or resistance of cancer cells to cytotoxic T lymphocyte-mediated toxicity.

Jason Moffat

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Nov. 9, 2020

Academic Institutions and Nonprofits only

#140961

Knockout library targeting human genes involved in cellular glycosylation.

Sriram Neelamegham

Zhu et al Glycobiology. 2020 Aug 8. pii: 5889976.

Sept. 9, 2020

Academic Institutions and Nonprofits only

#163966

Knockout library targeting mouse metabolic genes.

Alec Kimmelman

Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

July 1, 2021

Academic Institutions and Nonprofits only

#243681

For stable recombination of nearly all human GPCRs with unique molecular identifiers.

Jonathan Schlebach

Tedman et al bioRxiv 2025.09.19.677468

Oct. 27, 2025

Academic Institutions and Nonprofits only

#206249

The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

Kivanc Birsoy

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Aug. 29, 2024

Academic Institutions and Nonprofits only

#206248

The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

Kivanc Birsoy

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Aug. 29, 2024

Academic Institutions and Nonprofits only

#155257

Lineage tracing library

Joan Brugge, Aviv Regev

Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

Oct. 15, 2021

Academic Institutions and Nonprofits only

#113585

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

Sidi Chen

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

July 23, 2019

Academic Institutions and Nonprofits only

#221409

gRNA library to test the impact of transporters on biological processes

RESOLUTE Consortium, Giulio Superti-Furga

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Sept. 13, 2024

Academic Institutions and Nonprofits only