375 results

1. Self-targeting epegRNA library, Tiled edits (lRM001)

   Pooled Library

   #227708

   Purpose

   CRISPR guide RNA library for prime editing

   Depositor

   Brittany Adamson

   Article

   Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   Jan. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

2. Human ABC Transporter Knockout Sub-library with UMIs

   Pooled Library

   #221410

   Purpose

   gRNA library to test the impact of transporters on biological processes (subset: ABC transporters and controls)

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

3. SARS-CoV-2 RBD EG.5 SSM Library

   Pooled Library

   #1000000246

   Depositor

   Tyler Starr

   Available since

   Sept. 6, 2024

   Availability

   Academic Institutions and Nonprofits only

4. SARS-CoV-2 RBD FLip SSM Library

   Pooled Library

   #1000000247

   Depositor

   Tyler Starr

   Available since

   Sept. 6, 2024

   Availability

   Academic Institutions and Nonprofits only

5. CHyMErA LbCas12a Nuclease Optimization hgRNA Library

   Pooled Library

   #209734

   Purpose

   CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

6. CHyMErA AsCas12a Nuclease Optimization hgRNA Library

   Pooled Library

   #209735

   Purpose

   CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

   Depositor

   Thomas Gonatopoulos-Pournatzis

   Article

   Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 20, 2024

   Availability

   Academic Institutions and Nonprofits only

7. DHFR Saturation Mutagenesis Library - Q33S TYMS

   Pooled Library

   #1000000196

   Depositor

   Kimberly Reynolds

   Available since

   May 8, 2024

   Availability

   Academic Institutions and Nonprofits only

8. DHFR Saturation Mutagenesis Library - R166Q TYMS

   Pooled Library

   #1000000195

   Depositor

   Kimberly Reynolds

   Available since

   May 8, 2024

   Availability

   Academic Institutions and Nonprofits only

9. DHFR Saturation Mutagenesis Library - WT TYMS

   Pooled Library

   #1000000194

   Depositor

   Kimberly Reynolds

   Available since

   May 8, 2024

   Availability

   Academic Institutions and Nonprofits only

10. PBbtCRISPRko.v1

    Pooled Library

    #213928

    Purpose

    Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

    Depositor

    Wenfang Spring Tan

    Article

    Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    April 9, 2024

    Availability

    Academic Institutions and Nonprofits only