We narrowed to 178 results for: puro

1. hCRISPRi_dual_1_2

   Pooled Library

   #187246

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Marco Jost, Jonathan Weissman

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available Since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

2. hCRISPRa_dual_1_2

   Pooled Library

   #187249

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Marco Jost, Jonathan Weissman

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available Since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

3. Mouse sgRNA library Gouda in pRDA_118 backbone

   Pooled Library

   #136987

   Purpose

   Designed for assays with limited cell numbers with 2 guides per gene. Compatible with John Doench’s Brie mouse genome-wide library.

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

4. FNLCR CRISPRa Cell Surface

   Pooled Library

   #207471

   Purpose

   CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

   Depositor

   Raj Chari

   Article

   Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

5. MORF library without GFP and mCherry controls

   Pooled Library

   #192821

   Purpose

   Barcoded transcription factor ORF library for high throughput screening

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Jan. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

6. MinLibCas9

   Pooled Library

   #164896

   Purpose

   Genome-wide knockout library designed with two sgRNAs per gene.

   Depositor

   Mathew Garnett

   Article

   Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   May 20, 2021

   Availability

   Academic Institutions and Nonprofits only

7. mTORC1 Focused library

   Pooled Library

   #164084

   Purpose

   Knockout library targeting human genes required for mTORC1 activation and inhibition.

   Depositor

   David Sabatini

   Article

   Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Jan. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

8. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

   Pooled Library

   #75317

   Purpose

   Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

9. Human sgRNA library Gattinara in pRDA_118 backbone

   Pooled Library

   #136986

   Purpose

   Designed for assays with limited cell numbers with 2 guides per gene. Compatible with John Doench’s Brunello human genome-wide library.

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

10. BARBEKO sgRNA library

    Pooled Library

    #174163

    Purpose

    Cytosine base editors for genome-scale knockout screens in human cells. Targets gene start codons, splice sites, or introduces premature termination codons.

    Depositor

    Wensheng Wei

    Article

    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only

11. DNA repair library with 1,573 sgRNAs

    Pooled Library

    #177663

    Purpose

    CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available Since

    July 11, 2023

    Availability

    Academic Institutions and Nonprofits only

12. hCRISPRi_dual_5_6

    Pooled Library

    #187248

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

13. CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell lines

    Pooled Library

    #86539

    Depositor

    Jonathan Weissman

    Article

    Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

14. hCRISPRi_dual_3_4

    Pooled Library

    #187247

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

15. Sabatini/Lander Lab Ras synthetic lethal candidate focused human sgRNA library in lentiCRISPRv1

    Pooled Library

    #92352

    Purpose

    Focused gRNA library that targets synthetic lethal candidate and control genes with oncogenic Ras.

    Depositor

    Eric Lander, David Sabatini

    Article

    Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

    Species

    Homo sapiens

    Available Since

    June 7, 2017

    Availability

    Academic Institutions and Nonprofits only

16. hCRISPRa_dual_3_4

    Pooled Library

    #187250

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

17. hCRISPRa_dual_5_6

    Pooled Library

    #187251

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

18. DNA repair library with 336 sgRNAs

    Pooled Library

    #177664

    Purpose

    CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available Since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

19. Murine cell surface protein knockout (McspKO) library

    Pooled Library

    #200445

    Purpose

    Knockout library targeting mouse cell surface genes.

    Depositor

    Junjie Chen

    Article

    Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR, Lentiviral, and Mouse Targeting

    Available Since

    Oct. 26, 2023

    Availability

    Academic Institutions and Nonprofits only

20. Bison sgRNA library

    Pooled Library

    #169942

    Purpose

    Knockout library targeting ubiquitin ligases, deubiquitinases, and control genes.

    Depositor

    Benjamin Ebert

    Article

    Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

    Use

    Lentiviral

    Available Since

    Sept. 9, 2021

    Availability

    Academic Institutions and Nonprofits only