We narrowed to 187 results for: GRN

1. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

2. MinLibCas9

   Pooled Library

   #164896

   Purpose

   Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

   Depositor

   Mathew Garnett

   Article

   Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 20, 2021

   Availability

   Academic Institutions and Nonprofits only

3. Human SLC SAM Library

   Pooled Library

   #132561

   Purpose

   Expresses gRNAs for activation of human Solute Carrier family genes

   Depositor

   Giulio Superti-Furga

   Article

   Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 18, 2020

   Availability

   Academic Institutions and Nonprofits only

4. Splicing-targeting CRISPR-Cas9 library for human lncRNAs

   Pooled Library

   #119977

   Purpose

   The CRISPR sgRNA library was designed to target the 5' or 3' splice sites of lncRNAs in genome-scale, in order to knockout the targeted lncRNAs.

   Depositor

   Wensheng Wei

   Article

   Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   March 27, 2019

   Availability

   Academic Institutions and Nonprofits only

5. Human CRISPR Poison Exon Knockout Library

   Pooled Library

   #138084

   Purpose

   The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

   Depositor

   Robert Bradley

   Article

   Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   March 6, 2020

   Availability

   Academic Institutions and Nonprofits only

6. Oxford Drosophila melanogaster Genome-wide CRISPR Library

   Pooled Library

   #64750

   Purpose

   A genome-wide CRISPR library covering 13,501 genes (98.8% of the Drosophila melanogaster genome), among which 8,989 genes are targeted by three or more independent single guide RNAs (sgRNAs).

   Depositor

   Ji-Long Liu

   Article

   Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

   Expression

   Insect

   Species

   Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

   Use

   CRISPR

   Available since

   March 7, 2016

   Availability

   Academic Institutions and Nonprofits only

7. Liu Lab MusCK Library A

   Pooled Library

   #174196

   Purpose

   MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

   Depositor

   Xiaole Shirley Liu

   Article

   Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

8. Liu Lab MusCK Library B

   Pooled Library

   #174197

   Purpose

   MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

   Depositor

   Xiaole Shirley Liu

   Article

   Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Oct. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

9. ALL-PAM sensor Library

   Pooled Library

   #179219

   Purpose

   10 human and mouse sgRNAs each where for each sgRNA the tethered target site has 1 of 64 possible 3 bp PAM sequences.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

10. Toronto KnockOut Library (TKOv1)

    Pooled Library

    #1000000069

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Stephane Angers, Jason Moffat

    Available since

    Jan. 28, 2016

    Availability

    Academic Institutions and Nonprofits only

11. Human SAM library in lentiSAMv2 backbone

    Pooled Library

    #1000000078

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    Feng Zhang

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

12. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Unassigned1

    Pooled Library

    #1000000127

    Purpose

    CRISPR gRNA mouse knockout pooled library - Unassigned1

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

13. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Unassigned2

    Pooled Library

    #1000000128

    Purpose

    CRISPR gRNA mouse knockout pooled library - Unassigned2

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

14. Xiaole Shirley Liu lab Human CRISPR lentiviral library

    Pooled Library

    #1000000132

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Xiaole Shirley Liu

    Available since

    June 13, 2018

    Availability

    Academic Institutions and Nonprofits only

15. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Membrane proteins

    Pooled Library

    #1000000124

    Purpose

    CRISPR gRNA mouse knockout pooled library - Membrane proteins

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

16. Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

    Pooled Library

    #1000000083

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human kinome

    Depositor

    David Root, John Doench

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

17. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Gene Expression

    Pooled Library

    #1000000123

    Purpose

    CRISPR gRNA mouse knockout pooled library - Gene expression

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

18. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Apoptosis and cancer

    Pooled Library

    #1000000121

    Purpose

    CRISPR gRNA mouse knockout pooled library - Apoptosis and cancer

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

19. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Stress Proteostasis

    Pooled Library

    #1000000125

    Purpose

    CRISPR gRNA mouse knockout pooled library - Stress proteostasis

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

20. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Mouse unique 2

    Pooled Library

    #1000000130

    Purpose

    CRISPR gRNA mouse knockout pooled library - Mouse Unique2

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only